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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort
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Citation:
J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x Epub:
Yes Abstract:
Congenital heart defects (CHDs), the most common congenital human birth anomalies, involves complex genetic factors. Wnt/β-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S. Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort. J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x. |
tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis
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Citation:
Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7 Epub:
Not Epub Abstract:
Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour of endothelial cells (ECs) as they... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN. tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis. Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7. |
The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand
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Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/547836 Epub:
Not Epub Abstract:
[no abstract included] Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Rats Sprague-Dawley male Citation Extract: Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. bioRxiv. 2019;[Preprint] doi:10.1101/547836. |
A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
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Citation:
Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5 Epub:
Not Epub Abstract:
Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F. A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation. Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5. |
TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways
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Citation:
Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17 Epub:
Not Epub Abstract:
Steroid-resistant nephrotic syndrome (SRNS) is characterized by high-range proteinuria and most often focal and segmental... Organism or Cell Type:
zebrafish Citation Extract: Dorval G, Kuzmuk V, Gribouval O, Welsh GI, Bierzynska A, Schmitt A, Miserey-Lenkei S, Koziell A, Haq S, Benmerah A, Mollet G, Boyer O, Saleem MA, Antignac C.. TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways. Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17. |
Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model
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Citation:
Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x Epub:
Not Epub Abstract:
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality in humans mainly due to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A. Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model. Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x. |
Dynamin binding protein is required for Xenopus laevis kidney development
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Citation:
Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143 Epub:
Yes Abstract:
The adult human kidney contains over one million nephrons, with each nephron consisting of a tube containing segments that have... Organism or Cell Type:
Xenopus laevis Citation Extract: DeLay BD, Baldwin TA, Miller RK. Dynamin binding protein is required for Xenopus laevis kidney development. Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143. |
Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1
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Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008 Epub:
Yes Abstract:
Successful mitosis requires that cyclin B1:CDK1 ki-nase activity remains high until chromosomes arecorrectly aligned on the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Levasseur MD, Thomas C, Davies OR, Higgins JMG, Madgwick S. Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008. |
Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish
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Citation:
Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8 Epub:
Not Epub Abstract:
We have previously demonstrated the pro-tumoral role of neutrophils using a kras-induced zebrafish hepatocarcinogenesis model.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z. Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8. |
Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy
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Citation:
Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print] Epub:
Not Epub Abstract:
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M. Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy. Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print]. |