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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function

Authors:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA
Citation:
Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081.
Epub:
Not Epub
Abstract:
Joubert syndrome (JBTS) is an inherited autosomal recessive disorder associated with cerebellum and brainstem malformation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA. Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081. .

Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos

Authors:
Vázquez-Diez C, Paim LMG, FitzHarris G
Citation:
Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print]
Epub:
Yes
Abstract:
Chromosome segregation errors during mammalian preimplantation development cause "mosaic" embryos comprising a...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Vázquez-Diez C, Paim LMG, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print].

BMP signaling is required for amphioxus tail regeneration

Authors:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S
Citation:
Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print]
Epub:
Yes
Abstract:
Amphioxus, a cephalochordate, is an ideal animal in which to address questions about the evolution of regenerative ability and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Branchiostoma japonicum (amphioxus)
Citation Extract:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S. BMP signaling is required for amphioxus tail regeneration. Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print].

BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish

Authors:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q
Citation:
PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996
Epub:
Not Epub
Abstract:
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q. BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996.

A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells

Authors:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/516203
Epub:
Not Epub
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) maintain the vertebrate blood system throughout life and their emergence from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R. A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells. bioRxiv. 2019;[Preprint] doi:10.1101/516203.

A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish

Authors:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/512038
Epub:
Not Epub
Abstract:
The zebrafish pectoral fin is an in vivo model for vertebrate limb formation, well suited to investigate the integration of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M. A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish. bioRxiv. 2019;[Preprint] doi:10.1101/512038.

Delta/Notch signaling controls neuroepithelial morphogenesis in the zebrafish spinal cord

Authors:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M
Citation:
bioRxiv. 2019:[Preprint] doi:10.1101/517714
Epub:
Not Epub
Abstract:
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M. Delta/Notch signaling controls neuroepithelial morphogenesis in the zebrafish spinal cord. bioRxiv. 2019:[Preprint] doi:10.1101/517714.

Piezo1 is required for outflow tract and aortic valve development

Authors:
Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Beroud GC, Avierinos JF, Lebon G, Zaffran S, Jopling C
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/528588
Epub:
Not Epub
Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Beroud GC, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 is required for outflow tract and aortic valve development. bioRxiv. 2019;[Preprint] doi:10.1101/528588.

CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses

Authors:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L
Citation:
Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071
Epub:
Not Epub
Abstract:
Infection by rapidly growing Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF), a genetic disease...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L. CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses. Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071.

Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate

Authors:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW
Citation:
Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w
Epub:
Not Epub
Abstract:
Tissue internalisation is a key morphogenetic mechanism by which embryonic tissues generate complex internal organs and a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW. Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w.

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