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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients

Authors:
Alshareef A, Irwin MS, Gupta N, Zhang H-F, Haque M, Findlay SD, Seong BKA, Lai J, Rayis M, Al-Dandan S, Lai R
Citation:
Oncotarget. 2018; 9:10698-713. doi:10.18632/oncotarget.24216
Epub:
Not Epub
Abstract:
ALK missense mutations are detected in 8% of neuroblastoma (NB) tumors at diagnosis and confer gain-of-function oncogenic...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: human neuroblastoma cell lines
Citation Extract:
Alshareef A, Irwin MS, Gupta N, Zhang H-F, Haque M, Findlay SD, Seong BKA, Lai J, Rayis M, Al-Dandan S, Lai R. The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients. Oncotarget. 2018; 9:10698-713. doi:10.18632/oncotarget.24216.

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo

Authors:
Prabhudesai S, Koceja1 C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R
Citation:
Front Cell Dev Biol. 2018;6:14. doi:10.3389/fcell.2018.00014
Epub:
Not Epub
Abstract:
The cystathionine ß-synthase (CBS) is a critical enzyme in the transsulfuration pathway and is responsible for the synthesis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prabhudesai S, Koceja1 C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R. Cystathionine β-Synthase Is Necessary for Axis Development in Vivo. Front Cell Dev Biol. 2018;6:14. doi:10.3389/fcell.2018.00014.

Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo

Authors:
Barriga EH, Franze K, Charras G, Mayor R
Citation:
Nature. 2018 Feb 14. doi: 10.1038/nature25742. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Collective cell migration is essential for morphogenesis, tissue remodelling and cancer invasion. In vivo, groups of cells move...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Barriga EH, Franze K, Charras G, Mayor R. Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo. Nature. 2018 Feb 14. doi: 10.1038/nature25742. [Epub ahead of print].

Forebrain Electrophysiological Recording in Larval Zebrafish

Authors:
Baraban SC
Citation:
J Vis Exp. 2013;(71):e50104. doi:10.3791/50104
Epub:
Not Epub
Abstract:
Epilepsy affects nearly 3 million people in the United States and up to 50 million people worldwide. Defined as the occurrence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baraban SC. Forebrain Electrophysiological Recording in Larval Zebrafish. J Vis Exp. 2013;(71):e50104. doi:10.3791/50104.

Visualization of Craniofacial Development in the sox10: kaede Transgenic Zebrafish Line Using Time-lapse Confocal Microscopy

Authors:
Gfrerer L, Dougherty M, Liao EC
Citation:
J Vis Exp. 2013;(79):e50525, doi:10.3791/50525
Epub:
Not Epub
Abstract:
Vertebrate palatogenesis is a highly choreographed and complex developmental process, which involves migration of cranial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gfrerer L, Dougherty M, Liao EC. Visualization of Craniofacial Development in the sox10: kaede Transgenic Zebrafish Line Using Time-lapse Confocal Microscopy. J Vis Exp. 2013;(79):e50525, doi:10.3791/50525.

Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis

Authors:
Ohk J, Jung H
Citation:
J Vis Exp. 2017;(123):e55652. doi:10.3791/55652
Epub:
Not Epub
Abstract:
Blood vessels supply oxygen and nutrients throughout the body, and the formation of the vascular network is under tight...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Ohk J, Jung H. Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis. J Vis Exp. 2017;(123):e55652. doi:10.3791/55652.

Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae

Authors:
Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI
Citation:
J Vis Exp. 2016;(112),e54168, doi:10.3791/54168
Epub:
Not Epub
Abstract:
Surgical parabiosis of two animals of different genetic backgrounds creates a unique scenario to study cell-intrinsic versus...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. J Vis Exp. 2016;(112),e54168, doi:10.3791/54168.

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Authors:
Bernut A, Dupont C, Sahuquet A, Herrmann JL, Lutfalla G, Kremer, L
Citation:
J Vis Exp. 2015;(103),e53130, doi:10.3791/53130
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) embryos are increasingly used as an infection model to study the function of the vertebrate innate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bernut A, Dupont C, Sahuquet A, Herrmann JL, Lutfalla G, Kremer, L. Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos. J Vis Exp. 2015;(103),e53130, doi:10.3791/53130.

Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B

Authors:
Novas R, Cardenas-Rodriguez M, Lepanto P, Fabregat M, Rodao M, Fariello MI, Ramos M, Davison C, Casanova G, Alfaya L, Lecumberry F, González-Sapienza G, Irigoín F, Badano JL
Citation:
Sci Rep. 2018;8:3019. doi:10.1038/s41598-018-21329-6
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a ciliopathy characterized by retinal degeneration, obesity, polydactyly, renal disease and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Novas R, Cardenas-Rodriguez M, Lepanto P, Fabregat M, Rodao M, Fariello MI, Ramos M, Davison C, Casanova G, Alfaya L, Lecumberry F, González-Sapienza G, Irigoín F, Badano JL. Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B. Sci Rep. 2018;8:3019. doi:10.1038/s41598-018-21329-6.

Centrobin controls primary ciliogenesis in vertebrates

Authors:
Ogungbenro YA, Tena TC, David Gaboriau D, Lalor P, Dockery P, Philipp M, Morrison CG
Citation:
J Cell Biol. 2018;[Epub ahead of print] doi:10.1083/jcb.201706095
Epub:
Yes
Abstract:
The BRCA2 interactor, centrobin, is a centrosomal protein that has been implicated in centriole duplication and microtubule...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ogungbenro YA, Tena TC, David Gaboriau D, Lalor P, Dockery P, Philipp M, Morrison CG. Centrobin controls primary ciliogenesis in vertebrates. J Cell Biol. 2018;[Epub ahead of print] doi:10.1083/jcb.201706095.

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