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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury
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Citation:
Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318 Epub:
Not Epub Abstract:
Background: Lysine demethylase 4C (KDM4C) is a nuclear protein that is essential for histone modification and acts as an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pan HC, Chen YH, Fang WC, Wu VC, Sun CY. Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury. Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318. |
Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis
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Citation:
Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250 Epub:
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The orphan insulin receptor-related receptor (IRR) encoded by insrr gene is the third member of the insulin receptor family,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Korotkova DD, Gantsova EA, Goryashchenko AS, Eroshkin FM, Serova OV, Sokolov AS, Sharko F, Zhenilo SV, Martynova NY, Petrenko AG, Zaraisky AG, Deyev IE. Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis. Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250. |
Functions of block of proliferation 1 during anterior development in Xenopus laevis
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Citation:
PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022 Epub:
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Block of proliferation 1 (Bop1) is a nucleolar protein known to be necessary for the assembly of the 60S subunit of ribosomes.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ. Functions of block of proliferation 1 during anterior development in Xenopus laevis. PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022. |
PTEN inhibits AMPK to control collective migration
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Citation:
Nat Commun. 2022 Aug 11;13(1):4528. doi: 10.1038/s41467-022-31842-y Epub:
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Pten is one of the most frequently mutated tumour suppressor gene in cancer. PTEN is generally altered in invasive cancers such... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Peglion F, Capuana L, Perfettini I, Boucontet L, Braithwaite B, Colucci-Guyon E, Quissac E, Forsberg-Nilsson K, Llense F, Etienne-Manneville S. PTEN inhibits AMPK to control collective migration. Nat Commun. 2022 Aug 11;13(1):4528. doi: 10.1038/s41467-022-31842-y. |
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
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Elife. 2022 Aug 25;11:e81016. doi: 10.7554/eLife.81016. Online ahead of print Epub:
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The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Jang DG, Kwon KY, Kweon YC, Kim BG, Myung K, Lee HS, Young Park C, Kwon T, Park TJ. GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base. Elife. 2022 Aug 25;11:e81016. doi: 10.7554/eLife.81016. Online ahead of print. |
TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
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Citation:
Nucleic Acids Res. 2022 Aug 10:gkac659. doi: 10.1093/nar/gkac659. Online ahead of print Epub:
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Trimethylguanosine synthase 1 (TGS1) is a highly conserved enzyme that converts the 5′-monomethylguanosine cap of small nuclear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Schiavi ED, Gatti M, Artandi SE, Raffa GD. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Res. 2022 Aug 10:gkac659. doi: 10.1093/nar/gkac659. Online ahead of print. |
Co-option of the piRNA pathway to regulate neural crest specification
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Citation:
Sci Adv. 2022 Aug 12;8(32):eabn1441. doi: 10.1126/sciadv.abn1441. Epub 2022 Aug 10 Epub:
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Across Metazoa, Piwi proteins play a critical role in protecting the germline genome through piRNA-mediated repression of... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Galton R, Fejes-Toth K, Bronner ME. Co-option of the piRNA pathway to regulate neural crest specification. Sci Adv. 2022 Aug 12;8(32):eabn1441. doi: 10.1126/sciadv.abn1441. Epub 2022 Aug 10. |
Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis
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Citation:
EBioMedicine. 2022 Aug 2:104202. doi: 10.1016/j.ebiom.2022.104202. Online ahead of print Epub:
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Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with heterogeneous aetiology and a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chaytow H, Carroll E, Gordon D, Huang YT, van der Hoorn D, Smith HL, Becker T, Becker CG, Faller KME, Talbot K, Gillingwater TH. Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis. EBioMedicine. 2022 Aug 2:104202. doi: 10.1016/j.ebiom.2022.104202. Online ahead of print. |
Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates
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Citation:
EMBO J. 2022 Aug 4:e108536. doi: 10.15252/embj.2021108536. Online ahead of print Epub:
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During development, hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium and will expand in a transient... Delivery Method:
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zebrafish Citation Extract: Cacialli P, Mailhe MP, Wagner I, Merkler D, Golub R, Bertrand JY. Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates. EMBO J. 2022 Aug 4:e108536. doi: 10.15252/embj.2021108536. Online ahead of print. |
A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype
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Citation:
Biomedicines. 2022;10(8):1814. doi:10.3390/biomedicines10081814 Epub:
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NOP56 belongs to a C/D box small nucleolar ribonucleoprotein complex that is in charge of cleavage and modification of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Quelle-Regaldie A, Folgueira M, Yáñez J, Sobrido-Cameán D, Alba-González A, Barreiro-Iglesias A, Sobrido M-J, Sánchez L. A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype. Biomedicines. 2022;10(8):1814. doi:10.3390/biomedicines10081814. |