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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

The Nanog epigenetic remodeling complex was essential to vertebrate mesoderm evolution

Authors:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.08.507069
Epub:
Not Epub
Abstract:
Pluripotency defines the unlimited potential of cells in the primitive ectoderm of vertebrate embryos, from which all adult...
Link:
https://www.biorxiv.org/content/10.1101/2022.09.08.507069v1
Delivery Method:
microinjection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD. The Nanog epigenetic remodeling complex was essential to vertebrate mesoderm evolution. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.08.507069 .

The RhoGEF protein Plekhg5 regulates medioapical actomyosin dynamics of apical constriction during Xenopus gastrulation

Authors:
Baldwin AT, Popov IK, Keller R, Wallingford JB, Chang C
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506049
Epub:
Not Epub
Abstract:
Apical constriction results in apical surface reduction in epithelial cells and is a widely used mechanism for epithelial...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.506049v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Baldwin AT, Popov IK, Keller R, Wallingford JB, Chang C. The RhoGEF protein Plekhg5 regulates medioapical actomyosin dynamics of apical constriction during Xenopus gastrulation. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506049 .

Activation of ERK by altered RNA splicing in cancer

Authors:
Zhang Y, Siraj MA, Chakraborty P, Tseng R, Ku L-T, Das S, Dey A, Dwivedi SKD, Rao G, Zhang M, Yang D, Hossen MN, Ding W-Q, Fung K-M, Bhattacharya R, Escobar-Hoyos L, Mukherjee P
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.505957
Epub:
Not Epub
Abstract:
Many cancers carry change-of-function mutations affecting RNA splicing factors, however, less is known about the functional...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.505957v1
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Panc1, AsPc1
Citation Extract:
Zhang Y, Siraj MA, Chakraborty P, Tseng R, Ku L-T, Das S, Dey A, Dwivedi SKD, Rao G, Zhang M, Yang D, Hossen MN, Ding W-Q, Fung K-M, Bhattacharya R, Escobar-Hoyos L, Mukherjee P. Activation of ERK by altered RNA splicing in cancer. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.505957.

RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD

Authors:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L
Citation:
Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006
Epub:
Not Epub
Abstract:
BACKGROUND: Many psychiatric disorders share working memory (WM) impairment phenotype, yet the genetic causes remain unclear....
Link:
https://www.bpsgos.org/article/S2667-1743(22)00099-4/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L. RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD. Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006.

Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches

Authors:
Bina P, Taneyhill LA
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039
Epub:
Not Epub
Abstract:
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.506039v1
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bina P, Taneyhill LA. Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039 .

A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly

Authors:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P
Citation:
Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727
Epub:
Not Epub
Abstract:
Microcephaly presents in neurodevelopmental disorders with multiple aetiologies, including bi-allelic mutation in TUBGCP2, a...
Link:
https://www.mdpi.com/2073-4409/11/17/2727
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P. A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly. Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727.

eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?

Authors:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M
Citation:
Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075
Epub:
Not Epub
Abstract:
The eukaryotic initiation factor 4E binding protein (4E-BP) family is involved in translational control of cell proliferation...
Link:
https://www.mdpi.com/1422-0067/23/17/10075
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M. eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?. Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075.

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

Authors:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME
Citation:
Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3
Epub:
Not Epub
Abstract:
The sideroblastic anemias are a heterogeneous group of congenital and acquired hematological disorders whose morphological...
Link:
https://www.nature.com/articles/ng.359
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME. Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3.

Neuromuscular NMDA receptors regulate developmental synaptic depletion

Authors:
Joy E
Citation:
Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442
Epub:
Not Epub
Abstract:
[no abstract]
Link:
https://www.iomcworld.org/open-access/neuromuscular-nmda-receptors-regulate-developmental-synaptic-depletion.pdf
Delivery Method:
Vivo-Morpholino
Citation Extract:
Joy E. Neuromuscular NMDA receptors regulate developmental synaptic depletion. Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442.

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis

Authors:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X
Citation:
Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30
Epub:
Not Epub
Abstract:
The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa) remains controversial. Previously, we...
Link:
https://www.nature.com/articles/s12276-022-00837-6
Delivery Method:
exosomes
Organism or Cell Type:
mice BALB/c
Citation Extract:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X. MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30.

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