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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development

Authors:
Wareham LK, Whitener AE, Wu HJ, Wu SY, Mchaourab HS, Mortlock DP, Kuchtey RW, Kuchtey J
Citation:
Front Mol Biosci. 2022 Sep 6;9:989851. doi: 10.3389/fmolb.2022.989851. eCollection 2022
Epub:
Not Epub
Abstract:
Although mutations in ADAMTS10 have long been known to cause autosomal recessive Weill-Marchesani Syndrome which is...
Link:
https://www.frontiersin.org/articles/10.3389/fmolb.2022.989851/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wareham LK, Whitener AE, Wu HJ, Wu SY, Mchaourab HS, Mortlock DP, Kuchtey RW, Kuchtey J. Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development. Front Mol Biosci. 2022 Sep 6;9:989851. doi: 10.3389/fmolb.2022.989851. eCollection 2022.

AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells

Authors:
Revathidevi S, Hosomichi K, Natsume T, Nakaoka H, Fujito NT, Akatsuka H, Sato T, Munirajan AK, Inoue I
Citation:
Int J Mol Sci. 2022;23(19):11124. doi:10.3390/ijms231911124
Epub:
Not Epub
Abstract:
Cowden syndrome (CS) is a rare autosomal dominant disorder associated with multiple hamartomatous and neoplastic lesions in...
Link:
https://www.mdpi.com/1422-0067/23/19/11124/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Revathidevi S, Hosomichi K, Natsume T, Nakaoka H, Fujito NT, Akatsuka H, Sato T, Munirajan AK, Inoue I. AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells. Int J Mol Sci. 2022;23(19):11124. doi:10.3390/ijms231911124.

The Shape of the Jaw - Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization

Authors:
Reeck JC, Oxford JT
Citation:
J Dev Biol. 2022;10(4):40. doi:10.3390/jdb10040040
Epub:
Not Epub
Abstract:
The expression of the col11a1a gene is essential for normal skeletal development, affecting both cartilage and bone. Loss of...
Link:
https://www.mdpi.com/2221-3759/10/4/40
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reeck JC, Oxford JT. The Shape of the Jaw - Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization. J Dev Biol. 2022;10(4):40. doi:10.3390/jdb10040040.

A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish

Authors:
Li Y, Ning G, Kang B, Zhu J, Wang X-Y, Wang Q, Cai T
Citation:
Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229
Epub:
Not Epub
Abstract:
Hereditary hearing loss is a highly genetically heterogeneous disorder. More than 150 genes have been identified to link to...
Link:
https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddac229/6708355
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Ning G, Kang B, Zhu J, Wang X-Y, Wang Q, Cai T. A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish. Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229.

Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish

Authors:
Kidokoro H, Saijoh Y, Schoenwolf GC
Citation:
Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7
Epub:
Not Epub
Abstract:
Clockwise rotation of the primitive heart tube, a process regulated by restricted left-sided Nodal signaling, is the first...
Link:
https://www.nature.com/articles/s42003-022-03826-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kidokoro H, Saijoh Y, Schoenwolf GC. Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish. Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7.

Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish

Authors:
Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Sulej A, Abu NK, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C
Citation:
Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6
Epub:
Not Epub
Abstract:
Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although A...
Link:
https://www.nature.com/articles/s41467-022-33260-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Sulej A, Abu NK, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6.

Single-cell transcriptomics identifies conserved regulators of neuroglandular lineages

Authors:
Steger J, Cole AG, Denner A, Lebedeva T, Genikhovich G, Ries A, Reischl R, Taudes E, Lassnig M, Technau U
Citation:
Cell Rep. 2022;40(12):111370. doi:j.celrep.2022.111370
Epub:
Not Epub
Abstract:
Communication in bilaterian nervous systems is mediated by electrical and secreted signals; however, the evolutionary origin...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01202-5
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Steger J, Cole AG, Denner A, Lebedeva T, Genikhovich G, Ries A, Reischl R, Taudes E, Lassnig M, Technau U. Single-cell transcriptomics identifies conserved regulators of neuroglandular lineages. Cell Rep. 2022;40(12):111370. doi:j.celrep.2022.111370.

Dynamic Fibronectin Assembly and Remodeling by Leader Neural Crest Cells Prevents Jamming in Collective Cell Migration

Authors:
Martinson WD, McLennan R, Teddy JM, McKinney MC, Davidson LA, Baker RE, Byrne HM, Kulesa PM, Maini PK
Citation:
arXiv. 2022;[preprint] doi:10.48550/arXiv.2209.07794
Epub:
Not Epub
Abstract:
Collective cell migration plays an essential role in vertebrate development, yet the extent to which dynamically changing...
Link:
https://arxiv.org/abs/2209.07794
Delivery Method:
injection
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Martinson WD, McLennan R, Teddy JM, McKinney MC, Davidson LA, Baker RE, Byrne HM, Kulesa PM, Maini PK. Dynamic Fibronectin Assembly and Remodeling by Leader Neural Crest Cells Prevents Jamming in Collective Cell Migration. arXiv. 2022;[preprint] doi:10.48550/arXiv.2209.07794.

Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio

Authors:
Zhouyao H, Zimmer AM, Fehsenfeld S, Liebenstein T, Richter DO, Begemann G, Eck P, Perry SF, Weihrauch D
Citation:
J Exp Biol. 2022;jeb.244279. doi:10.1242/jeb.244279
Epub:
Not Epub
Abstract:
Ammonia excretion in fish excretory epithelia is a complex interplay of multiple membrane transport proteins and mechanisms....
Link:
https://journals.biologists.com/jeb/article-abstract/doi/10.1242/jeb.244279/276662/Characterization-of-two-novel-ammonia-transporters
Organism or Cell Type:
zebrafish
Citation Extract:
Zhouyao H, Zimmer AM, Fehsenfeld S, Liebenstein T, Richter DO, Begemann G, Eck P, Perry SF, Weihrauch D. Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio. J Exp Biol. 2022;jeb.244279. doi:10.1242/jeb.244279.

Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue

Authors:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC
Citation:
Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0
Epub:
Not Epub
Abstract:
In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage, dysregulation of repair, fibro-fatty...
Link:
https://www.nature.com/articles/s42003-022-03938-0
Organism or Cell Type:
mice, human
Citation Extract:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC. Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue. Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0.

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