You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis
|
Citation:
PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402 Epub:
Not Epub Abstract:
Impaired formation of the intrahepatic biliary network leads to cholestatic liver diseases, which are frequently associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghaffari K, Pierce LX, Roufaeil M, Gibson I, Tae K, Sahoo S, Cantrell JT, Andersson O, Lau J, Sakaguchi TF. NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis. PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402. |
Svep1 stabilises developmental vascular anastomosis in reduced flow conditions
|
Citation:
Development. 2022 Mar 15;149(6):dev199858. doi: 10.1242/dev.199858. Epub 2022 Mar 24. PMID: 35312765; PMCID: PMC8977097 Epub:
Not Epub Abstract:
Molecular mechanisms controlling the formation, stabilisation and maintenance of blood vessel connections remain poorly defined... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Coxam B, Collins RT, Hußmann M, Huisman Y, Meier K, Jung S, Bartels-Klein E, Szymborska A, Finotto L, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H. Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. Development. 2022 Mar 15;149(6):dev199858. doi: 10.1242/dev.199858. Epub 2022 Mar 24. PMID: 35312765; PMCID: PMC8977097. |
Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency
|
Citation:
Genet Med. 2021. doi:10.1038/s41436-021-01137-6 Epub:
Not Epub Abstract:
Purpose: Variants in NUS1 are associated with a congenital disorder of glycosylation, developmental and epileptic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu S-H, Wang T, Wiggins K, Louie RJ, Merino EF, Skinner C, Cassera MB, Meagher K, Goldberg P, Rismanchi N, Chen D, Lyons MJ, Flanagan-Steet H, Steet R. Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency. Genet Med. 2021. doi:10.1038/s41436-021-01137-6. |
Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep
|
Citation:
Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021 Epub:
Not Epub Abstract:
As a major protein of the polyhedral coat of coated pits and vesicles, clathrin molecules have been shown to play a... Delivery Method:
microinjection Organism or Cell Type:
Ovis aries (sheep oocytes) Citation Extract: Han Z, Hao X, Zhou CJ, Wang J, Wen X, Wang XY, Zhang DJ, Liang CG. Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep. Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021. |
miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury
|
Citation:
Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print Epub:
Not Epub Abstract:
This study aims to examine whether miR-31 promotes endogenous NSC proliferation and be used for spinal cord injury management.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Gao Y, Tian F, Du R, Yuan Y, Li P, Liu F, Wang C. miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury. Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print. |
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome
|
Citation:
Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4 Epub:
Yes Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare, invariably fatal childhood premature aging disorder caused by a pre-... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Puttaraju M, Jackson M, Klein S, Shilo A, Bennett CF, Gordon L, Rigo F, Misteli T. Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome. Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4. |
A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome
|
Citation:
Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11. Epub:
Not Epub Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder characterized by premature death from... Delivery Method:
peptide-linked; intravenous (i.v.) injection for mice Organism or Cell Type:
human progeric fibroblast cells; LMNAG/G mice Citation Extract: Erdos MR, Cabral WA, Tavarez UL, Cao K, Gvozdenovic-Jeremic J, Narisu N, Zerfas PM, Crumley S, Boku Y, Hanson G, Mourich DV, Kole R, Eckhaus MA, Gordon LB, Collins FS. A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome. Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11.. |
Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development
|
Citation:
Development. 2021 Oct 15;148(20):dev199691. doi: 10.1242/dev.199691. Epub 2021 Oct 22. PMID: 34568948 Epub:
Not Epub Abstract:
During early vertebrate heart development, the heart transitions from a linear tube to a complex asymmetric structure, a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Derrick CJ, Pollitt EJG, Sanchez Sevilla Uruchurtu A, Hussein F, Grierson AJ, Noël ES. Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development. 2021 Oct 15;148(20):dev199691. doi: 10.1242/dev.199691. Epub 2021 Oct 22. PMID: 34568948. |
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients
|
Citation:
EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328 Epub:
Not Epub Abstract:
DMD is a rare disorder characterized by progressive muscle degeneration and premature death. Therapy development is delayed by... Delivery Method:
i.v. injection Organism or Cell Type:
mice mdx Citation Extract: Signorelli M, Ebrahimpoor M, Veth O, Hettne K, Verwey N, García‐Rodríguez R, Tanganyika‐deWinter CL, Lopez Hernandez LB, Cedillo RE, Díaz BG, Magnusson OT, Mei H, Tsonaka R, Aartsma‐Rus A, Spitali P. Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients. EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328. |
Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families
|
Citation:
Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061 Epub:
Not Epub Abstract:
Isolated Microspherophakia (MSP) is an autosomal recessive disorder characterised by a smaller than normal spherical lens. Till... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Madhangi M, Dutta D, Show S, Bhat VK, Rather MI, Tiwari A, Singh N, Duvvari MR, Murthy GJ, Kumar A, Nongthomba U. Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families. Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061. |