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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties
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Citation:
Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693 Epub:
Not Epub Abstract:
A novel class of nucleotide analogues with a dioxane ring as central scaffold has been developed. Synthetic routes in two... Citation Extract: Hofmeister A, Jahn-Hofmann K, Krack A, Müller A, Kurz M, Scheidler S. Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties. Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693. |
Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis
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Citation:
J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494 Epub:
Not Epub Abstract:
Notch signaling governs crucial aspects of intercellular communication spanning antigen-presenting cells and T-cells. In this... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Balb/c mice and sometimes Leishmania donovani infections Citation Extract: Chandrakar P, Seth A, Rani A, Dutta M, Parmar N, Descoteaux A, Kar S. Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis. J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494 . |
Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates
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Citation:
Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2 Epub:
Not Epub Abstract:
TG2 is a multifunctional enzyme involved in several cellular processes and has emerging as a potential regulator of gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossin F, Costa R, Bordi M, D’Eletto M, Occhigrossi L, Farrace MG, Barlev N, Ciccosanti F, Muccioli S, Chieregato L, Szabo I, Fimia GM, Piacentini M, Leanza L. Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates. Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2. |
Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos
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Citation:
Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525 Epub:
Not Epub Abstract:
Cells dividing in the plane of epithelial tissues proceed by polarized constriction of the actomyosin contractile ring, leading... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hatte G, Prigent C, Tassan J-P. Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos. Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525. |
Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation
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Citation:
Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329 Epub:
Not Epub Abstract:
Cell penetrating peptides (CPPs) are being increasingly used as efficient vectors for intracellular delivery of biologically... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: spinal muscular atrophy (SMA) patient fibroblasts Citation Extract: Dastpeyman M, Karas JA, Amin A, Turner BJ, Shabanpoor F. Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation. Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329. |
hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies
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Citation:
Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print Epub:
Yes Abstract:
Introduction/aims: RNA binding proteins (RBPs) play an important role in skeletal muscle development and disease by regulating... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alexander MS, Hightower RM, Reid AL, Bennett AH, Iyer L, Slonim DK, Saha M, Kawahara G, Kunkel LM, Kopin AS, Gupta VA, Kang PB, Draper I. hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies. Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print. |
Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes
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Citation:
Current Research in Cell Biology, Volume 2, 2021, 100009, ISSN 2590-2636, https://doi.org/10.1016/j.crcbio.2021.100009 Epub:
Not Epub Abstract:
After completion of meiosis I, the oocyte immediately enters meiosis II and forms a metaphase II (MII) spindle without an... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Takei N, Sato K, Takada Y, Iyyappan R, Susor A, Yamamoto T, Kotani T. Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes. Current Research in Cell Biology, Volume 2, 2021, 100009, ISSN 2590-2636, https://doi.org/10.1016/j.crcbio.2021.100009. |
Mechanically sensitive HSF1 is a key regulator of left-right symmetry breaking in zebrafish embryos
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Citation:
iScience. 2023 Sep 9;26(10):107864. doi: 10.1016/j.isci.2023.107864. PMID: 37766982; PMCID: PMC10520531 Epub:
Not Epub Abstract:
The left-right symmetry breaking of vertebrate embryos requires nodal flow. However, the molecular mechanisms that mediate the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Du J, Li SK, Guan LY, Guo Z, Yin JF, Gao L, Kawanishi T, Shimada A, Zhang QP, Zheng LS, Liu YY, Feng XQ, Zhao L, Chen DY, Takeda H, Fan YB. Mechanically sensitive HSF1 is a key regulator of left-right symmetry breaking in zebrafish embryos. iScience. 2023 Sep 9;26(10):107864. doi: 10.1016/j.isci.2023.107864. PMID: 37766982; PMCID: PMC10520531. |
Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism
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Citation:
Elife. 2021 Aug 27;10:e66483. doi: 10.7554/eLife.66483. PMID: 34448451; PMCID: PMC8460252 Epub:
Not Epub Abstract:
The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. Elife. 2021 Aug 27;10:e66483. doi: 10.7554/eLife.66483. PMID: 34448451; PMCID: PMC8460252. |
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production
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Citation:
Dev Cell. 2021 Mar 8;56(5):627-640.e5. doi: 10.1016/j.devcel.2021.02.006. Epub 2021 Mar 1 Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise during embryonic development and are essential for sustaining the blood... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weinreb JT, Ghazale N, Pradhan K, Gupta V, Potts KS, Tricomi B, Daniels NJ, Padgett RA, De Oliveira S, Verma A, Bowman TV. Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. Dev Cell. 2021 Mar 8;56(5):627-640.e5. doi: 10.1016/j.devcel.2021.02.006. Epub 2021 Mar 1. |