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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome

Authors:
Luo M, Lin Z, Zhu T, Jin M, Meng D, He R, Cao Z, Shen Y, Lu C, Cai R, Zhao Y, Wang X, Li H, Wu S, Zou X, Luo G, Cao L, Huang M, Jiao H, Gao H, Sui R, Zhao C, Ma X, Cao M
Citation:
Genet Med. 2021 Feb 2. doi: 10.1038/s41436-021-01106-z. Online ahead of print
Epub:
Yes
Abstract:
Purpose: Ciliopathies are a group of disorders caused by defects of the cilia. Joubert syndrome (JBTS) is a recessive and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luo M, Lin Z, Zhu T, Jin M, Meng D, He R, Cao Z, Shen Y, Lu C, Cai R, Zhao Y, Wang X, Li H, Wu S, Zou X, Luo G, Cao L, Huang M, Jiao H, Gao H, Sui R, Zhao C, Ma X, Cao M. Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome. Genet Med. 2021 Feb 2. doi: 10.1038/s41436-021-01106-z. Online ahead of print.

Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification

Authors:
Liu K-C, Villasenor A, Schmitner N, Radros N, Rautio L, Reischauer S, Stainier DYR, Andersson O
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.01.429189
Epub:
Not Epub
Abstract:
To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu K-C, Villasenor A, Schmitner N, Radros N, Rautio L, Reischauer S, Stainier DYR, Andersson O. Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.01.429189 .

Retinoic acid production, regulation, and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification

Authors:
Dubey A, Yu J, Liu T, Kane MA, Saint-Jeannet J-P
Citation:
Development. 2021;148(4):dev193227 doi:10.1242/dev.193227
Epub:
Yes
Abstract:
All paired sensory organs arise from a common precursor domain called the pre-placodal region (PPR). In Xenopus, Zic1 non-cell...
Organism or Cell Type:
Xenopus
Citation Extract:
Dubey A, Yu J, Liu T, Kane MA, Saint-Jeannet J-P. Retinoic acid production, regulation, and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification. Development. 2021;148(4):dev193227 doi:10.1242/dev.193227.

RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes

Authors:
Qin H, Qu Y, Yuan Y-F, Li Y-Y, Qiao J
Citation:
Front Cell Devel Biol. 2021;9:113. doi:10.3389/fcell.2021.635728
Epub:
Not Epub
Abstract:
RBM14 is an RNA-binding protein that regulates spindle integrity in mitosis; however, its functions during meiosis are still...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Qin H, Qu Y, Yuan Y-F, Li Y-Y, Qiao J. RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes. Front Cell Devel Biol. 2021;9:113. doi:10.3389/fcell.2021.635728 .

Sfxn1 is essential for erythrocyte maturation via facilitating hemoglobin production in zebrafish

Authors:
Bao B, An W, Lu Q, Wang Y, Lu Z, Tu J, Zhang H, Duan Y, Yuan W, Zhu X, Jia H
Citation:
Biochem Biophys Acta - Molecular basis of disease. 2021;[Epub ahead of print] doi:10.1016/j.bbadis.2021.166096
Epub:
Yes
Abstract:
Previous reports revealed that mutation of mitochondrial inner-membrane located protein SFXN1 led to pleiotropic hematological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bao B, An W, Lu Q, Wang Y, Lu Z, Tu J, Zhang H, Duan Y, Yuan W, Zhu X, Jia H. Sfxn1 is essential for erythrocyte maturation via facilitating hemoglobin production in zebrafish. Biochem Biophys Acta - Molecular basis of disease. 2021;[Epub ahead of print] doi:10.1016/j.bbadis.2021.166096.

Hallmarks of primary neurulation are conserved in the zebrafish forebrain

Authors:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster RM
Citation:
Commun Biol. 2021 Jan 29;4(1):147. doi: 10.1038/s42003-021-01655-8
Epub:
Not Epub
Abstract:
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster RM. Hallmarks of primary neurulation are conserved in the zebrafish forebrain. Commun Biol. 2021 Jan 29;4(1):147. doi: 10.1038/s42003-021-01655-8.

Protein 14-3-3 eta (YWHAH) is essential for normal meiotic spindle assembly during in vitro maturation of mouse oocytes

Authors:
De S, Davis S, Letwin D, Mozena C, Kline D
Citation:
Am Soc Cell Bio Conference. 2012;Poster 1967
Epub:
Not Epub
Abstract:
The 14-3-3 (YWHA) proteins are known to be central mediators in various cellular signaling pathways regulating...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
De S, Davis S, Letwin D, Mozena C, Kline D. Protein 14-3-3 eta (YWHAH) is essential for normal meiotic spindle assembly during in vitro maturation of mouse oocytes. Am Soc Cell Bio Conference. 2012;Poster 1967.

Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function

Authors:
Nommick A, Boutin C, Rosnet O, Bazellieres E, Thome V, Loiseau E, Viallat A, Kodjabachian L
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.30.428946
Epub:
Not Epub
Abstract:
Ciliated epithelia perform a variety of essential functions across animal evolution, ranging from locomotion of marine...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nommick A, Boutin C, Rosnet O, Bazellieres E, Thome V, Loiseau E, Viallat A, Kodjabachian L. Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.30.428946.

Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m6A methylation level to cause lipid metabolism disorder in zebrafish

Authors:
Sun L, Gao M, Qian Q, Guo Z, Zhu P, Wang X, Wang H
Citation:
Sci Total Environ. 2021 Jan 22;770:145285. doi: 10.1016/j.scitotenv.2021.145285. Online ahead of print
Epub:
Not Epub
Abstract:
Chronic exposure of triclosan (TCS) to zebrafish triggers high incidence of fatty liver and hepatitis; however, the underlying...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Gao M, Qian Q, Guo Z, Zhu P, Wang X, Wang H. Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m6A methylation level to cause lipid metabolism disorder in zebrafish. Sci Total Environ. 2021 Jan 22;770:145285. doi: 10.1016/j.scitotenv.2021.145285. Online ahead of print.

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

Authors:
Lu JY, Chang L, Li T, Wang T, Yin Y, Zhan G, Han X, Zhang K, Tao Y, Percharde M, Wang L, Peng Q, Yan P, Zhang H, Bi X, Shao W, Hong Y, Wu Z, Ma R, Wang P, Li We, Zhang J, Chang Z, Hou Y, Zhu B, Ramalho-Santos M, Li P, Xie W, Na J, Sun Y, Shen X
Citation:
Cell Res. 2021. doi:10.1038/s41422-020-00466-6
Epub:
Not Epub
Abstract:
Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Lu JY, Chang L, Li T, Wang T, Yin Y, Zhan G, Han X, Zhang K, Tao Y, Percharde M, Wang L, Peng Q, Yan P, Zhang H, Bi X, Shao W, Hong Y, Wu Z, Ma R, Wang P, Li We, Zhang J, Chang Z, Hou Y, Zhu B, Ramalho-Santos M, Li P, Xie W, Na J, Sun Y, Shen X. Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome. Cell Res. 2021. doi:10.1038/s41422-020-00466-6.

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