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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts
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Citation:
Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 Epub:
Not Epub Abstract:
The Cpi-17 (ppp1r14) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lang I, Virk G, Zheng DC, Young J, Nguyen MJ, Amiri R, Fong M, Arata A, Chadaideh KS, Walsh S, Weiser DC. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 . |
THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis
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Citation:
PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953 Epub:
Not Epub Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953. |
Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast
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Citation:
PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414 Epub:
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The host innate immune system has developed elegant processes for the detection and clearance of invasive fungal pathogens.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scherer AK, Blair BA, Park J, Seman BG, Kelley JB, Wheeler RT. Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast. PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414. |
NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation
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Citation:
J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275 Epub:
Not Epub Abstract:
The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic protein 1 (HEM-1), encodes a hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Groß M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S. NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275. |
Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae
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Citation:
Elife. 2021 May 6;10:e61804. doi: 10.7554/eLife.61804. PMID: 33955353; PMCID: PMC8137141 Epub:
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Inducing regeneration in injured spinal cord represents one of modern medicine's greatest challenges. Research from a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hamilton AM, Balashova OA, Borodinsky LN. Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae. Elife. 2021 May 6;10:e61804. doi: 10.7554/eLife.61804. PMID: 33955353; PMCID: PMC8137141. |
Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts
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Citation:
Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2 Epub:
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Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Asokan N, Daetwyler S, Bernas SN, Schmied C, Vogler S, Lambert K, Wobus M, Wermke M, Kempermann G, Huisken J, Brand M, Bornhäuser M. Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts. Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2. |
SLC20A1 Is Involved in Urinary Tract and Urorectal Development
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Citation:
Front Cell Devel Biol. 2020;8:567. doi:10.3389/fcell.2020.00567 Epub:
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Previous studies in developing Xenopus and zebrafish reported that the phosphate transporter slc20a1a is expressed in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rieke JM, Zhang R, Braun D, Yilmaz Ö, Japp AS, Lopes FM, Pleschka M, Hilger AC, Schneider S, Newman WG, Beaman GM, Nordenskjöld A, Ebert A-K, Promm M, Rösch WH, Stein R, Hirsch K, Schäfer F-M, Schmiedeke E, Boemers TM, Lacher M, Kluth D, Gosemann J-H, Anderberg M, Barker G, Holmdahl G, Läckgren G, Keene D, Cervellione RM, Giorgio E, Di Grazia M, Feitz WFJ, Marcelis CLM, Van Rooij IALM, B Arend, Beckers GMA, Keegan CE, Sharma A, Dakal TC, Wittler L, Grote P, Zwink N, Jenetzky E, Brusco A, Thiele H, Ludwig M, Schweizer U, Woolf AS, Odermatt B, Reutter H. SLC20A1 Is Involved in Urinary Tract and Urorectal Development. Front Cell Devel Biol. 2020;8:567. doi:10.3389/fcell.2020.00567. |
Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development
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Citation:
Sci Rep. 2020 Aug 7;10(1):13321. doi: 10.1038/s41598-020-70152-5 Epub:
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Hypophosphatasia (HPP) is a rare genetic disease with diverse symptoms and a heterogeneous severity of onset with underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ohlebusch B, Borst A, Frankenbach T, Klopocki E, Jakob F, Liedtke D, Graser S. Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development. Sci Rep. 2020 Aug 7;10(1):13321. doi: 10.1038/s41598-020-70152-5. |
The Role of gfi1.2 in the Development of Zebrafish Inner Ear
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Citation:
Hearing Res. 2020 Aug 7;396:108055. doi: 10.1016/j.heares.2020.108055. Online ahead of print. Epub:
Not Epub Abstract:
Inner ear hair cells are mechanosensitive cells responsible for sensing and transmitting signals to the brain to be interpreted... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu R, Wang P, Chen X-W. The Role of gfi1.2 in the Development of Zebrafish Inner Ear. Hearing Res. 2020 Aug 7;396:108055. doi: 10.1016/j.heares.2020.108055. Online ahead of print.. |
Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects
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Citation:
Thyroid. 2020 Aug 10. doi: 10.1089/thy.2019.0828. Online ahead of print Epub:
Yes Abstract:
Background: Congenital hypothyroidism (CH) due to thyroid dysgenesis is a frequent congenital endocrine disorder for which the... Organism or Cell Type:
zebrafish Citation Extract: Vandernoot I, Haerlingen B, Gillotay P, Trubiroha A, Janssens V, Opitz R, Costagliola S. Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects. Thyroid. 2020 Aug 10. doi: 10.1089/thy.2019.0828. Online ahead of print. |