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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Rare heterozygous GDF6 variants in patients with renal anomalies
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Citation:
Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9 Epub:
Yes Abstract:
Although over 50 genes are known to cause renal malformation if mutated, the underlying genetic basis, most easily identified... Delivery Method:
injection into stage 39 tadpoles Organism or Cell Type:
Xenopus laevis Citation Extract: Martens H, Hennies I, Getwan M, Christians A, Weiss A-C, Brand F, Gjerstad AC, Christians A, Gucev Z, Geffers R, Seeman T, Kispert A, Tasic V, Bjerre A, Lienkamp SS, Haffner D, Weber RG. Rare heterozygous GDF6 variants in patients with renal anomalies. Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9. |
New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian
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Citation:
J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9 Epub:
Not Epub Abstract:
Nanos is a pan-metazoan germline marker, important for germ cell development and maintenance. In flies, Nanos also acts in... Delivery Method:
microinjection Organism or Cell Type:
Hydractinia echinata (cnidarian) Citation Extract: Kanska J, Frank U. New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian. J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9. |
Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site
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Citation:
PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020 Epub:
Not Epub Abstract:
ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Smith SJ, Towers N, Demetriou K, Mohun TJ. Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020. |
Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development
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Citation:
Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955 Epub:
Not Epub Abstract:
To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and postsynaptic neurons of the developing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES. Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development. Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955. |
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B
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Citation:
EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print Epub:
Yes Abstract:
Lysosomal degradation of the endoplasmic reticulum (ER) via autophagy (ER-phagy) is emerging as a critical regulator of cell... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print. |
PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development
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Citation:
Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782 Epub:
Not Epub Abstract:
Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Da’as SI, Aamer W, Hasan W, Al-Maraghi A, Al-Kurbi A, Kilani H, AlRayahi J, Zamel K, Stotland MA, Fakhro KA. PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development. Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782. |
RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration
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Citation:
FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print Epub:
Yes Abstract:
The proto-oncogene ets1 is highly expressed in the pre-migratory and migratory neural crest (NC), and has been implicated in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis & Xenopus tropicalis Citation Extract: Wang C, Qi X, Zhou X, Sun J, Cai D, Lu G, Chen X, Jiang Z, Yao YG, Chan WY, Zhao H. RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration. FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print. |
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
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Citation:
Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786 Epub:
Not Epub Abstract:
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute infection of the respiratory tract (COVID-19)... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Calu-3 human airway epithelial cells Citation Extract: Bestle D, Heindl MR, Limburg H, Lam van TV, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk H-D, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells. Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786. |
Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio)
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Citation:
J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753 Epub:
Yes Abstract:
Fishes living in fresh water counter the passive loss of salts by actively absorbing ions through specialized cells termed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Parker JJ, Zimmer AM, Perry SF. Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio). J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753. |
Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
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Citation:
PLoS Biol. 2020;18(7):e3000561. doi:10.1371/journal.pbio.3000561 Epub:
Not Epub Abstract:
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He M, Zhang R, Jiao S, Zhang F, Ye D, Wang H, Sun Y. Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors. PLoS Biol. 2020;18(7):e3000561. doi:10.1371/journal.pbio.3000561. |