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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12318 scientific papers returned from the database with the search filters currently being used below.

Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

Authors:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S
Citation:
Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y
Epub:
Not Epub
Abstract:
Cell fate decisions involved in vascular and hematopoietic embryonic development are still poorly understood. An ETS...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S. Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y.

Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

Authors:
Choe S, Huh TL, Rhee M
Citation:
Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281
Epub:
Not Epub
Abstract:
Trim45 is one of the RING (really interesting new gene) finger containing E3 ligase, which belongs to TRIM (Tripartite motif)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choe S, Huh TL, Rhee M. Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos. Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281.

CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia

Authors:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print
Epub:
Not Epub
Abstract:
Synchronized beating of cilia on multiciliated cells (MCCs) generates a directional flow of mucus across epithelia. This...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J. CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia. Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print.

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Authors:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T
Citation:
Elife. 2020 Nov 25;9:e59489. doi: 10.7554/eLife.59489. PMID: 33236989; PMCID: PMC7725503
Epub:
Not Epub
Abstract:
Wnt3 proteins are lipidated and glycosylated signaling molecules that play an important role in zebrafish neural patterning and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T. Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions. Elife. 2020 Nov 25;9:e59489. doi: 10.7554/eLife.59489. PMID: 33236989; PMCID: PMC7725503.

Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication

Authors:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW
Citation:
Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754
Epub:
Not Epub
Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: A549
Citation Extract:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW. Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication. Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754.

Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis

Authors:
Gore SV, James EJ, Huang LC, Park JJ, Berghella A, Thompson AC, Cline HT, Aizenman CD
Citation:
Elife. 2021 Jul 20;10:e62147. doi: 10.7554/eLife.62147. PMID: 34282726; PMCID: PMC8315794
Epub:
Not Epub
Abstract:
Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive...
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gore SV, James EJ, Huang LC, Park JJ, Berghella A, Thompson AC, Cline HT, Aizenman CD. Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis. Elife. 2021 Jul 20;10:e62147. doi: 10.7554/eLife.62147. PMID: 34282726; PMCID: PMC8315794.

Functional characterization of a 'plant-like' HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

Authors:
Tripathi AM, Admoni Y, Fridrich A, Lewandowska M, Surm JM, Aharoni R, Moran Y
Citation:
Elife. 2022 Mar 15;11:e69464. doi: 10.7554/eLife.69464. PMID: 35289745; PMCID: PMC9098223
Epub:
Not Epub
Abstract:
While the biogenesis of microRNAs (miRNAs) in both animals and plants depends on the RNase III Dicer, its partner proteins are...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Tripathi AM, Admoni Y, Fridrich A, Lewandowska M, Surm JM, Aharoni R, Moran Y. Functional characterization of a 'plant-like' HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis. Elife. 2022 Mar 15;11:e69464. doi: 10.7554/eLife.69464. PMID: 35289745; PMCID: PMC9098223.

Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes

Authors:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y
Citation:
Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957
Epub:
Not Epub
Abstract:
Arginine vasopressin (Avp) is a conserved pleiotropic hormone that is known to regulate both water reabsorption and ion balance...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y. Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes. Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957.

Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism

Authors:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ
Citation:
Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Ethanol has diverse effects on nervous system development, which includes development and survival of GABAergic...
Organism or Cell Type:
zebrafish
Citation Extract:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ . Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism. Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print.

The Axenfeld-Rieger Syndrome Gene FOXC1 Contributes to Left-Right Patterning

Authors:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson AM, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ
Citation:
Genes (Basel). 2021 Jan 26;12(2):170. doi: 10.3390/genes12020170. PMID: 33530637; PMCID: PMC7912076
Epub:
Not Epub
Abstract:
Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left-right...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson AM, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ. The Axenfeld-Rieger Syndrome Gene FOXC1 Contributes to Left-Right Patterning. Genes (Basel). 2021 Jan 26;12(2):170. doi: 10.3390/genes12020170. PMID: 33530637; PMCID: PMC7912076.

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