You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production

Authors:
Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF
Citation:
Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9
Epub:
Not Epub
Abstract:
The DNA binding protein AT-rich interacting domain 3a (ARID3a)2 is expressed in healthy human hematopoietic cord blood...
Link:
https://www.sciencedirect.com/science/article/pii/S0008874920303610
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human hematopoietic stem progenitor cells (HSPCs)
Citation Extract:
Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF. TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production. Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9.

The tight junctions protein Claudin-5 limits endothelial cell motility

Authors:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Stephan A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J
Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237
Epub:
Yes
Abstract:
Steinberg's differential adhesion hypothesis suggests that adhesive mechanisms are important for sorting of cells and...
Link:
https://jcs.biologists.org/content/early/2020/12/11/jcs.248237
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Stephan A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J. The tight junctions protein Claudin-5 limits endothelial cell motility. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237.

The RNA helicase DDX3 induces neural crest by promoting AKT activity

Authors:
Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341
Epub:
Not Epub
Abstract:
Mutations in the RNA helicase DDX3 have emerged as a frequent cause of intellectual disability in humans. Because many patients...
Link:
https://dev.biologists.org/content/early/2020/12/09/dev.184341
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S. The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341.

16p12.1 deletion orthologs are expressed in motile neural crest cells and are important for regulating craniofacial development in Xenopus laevis

Authors:
Lasser M, Bolduc J, Murphy L, O'Brien C, Lee S, Girirajan S, Lowery L
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.11.421347
Epub:
Not Epub
Abstract:
Copy number variants (CNVs) associated with neurodevelopmental disorders are characterized by extensive phenotypic...
Link:
https://www.biorxiv.org/content/10.1101/2020.12.11.421347v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lasser M, Bolduc J, Murphy L, O'Brien C, Lee S, Girirajan S, Lowery L. 16p12.1 deletion orthologs are expressed in motile neural crest cells and are important for regulating craniofacial development in Xenopus laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.11.421347 .

Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis

Authors:
Lee H, Ismail T, Kim Y, Chae S, Ryu H-Y, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S
Citation:
Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265
Epub:
Not Epub
Abstract:
Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme...
Link:
https://www.mdpi.com/2076-3921/9/12/1265
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee H, Ismail T, Kim Y, Chae S, Ryu H-Y, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis. Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265.

CRISPR/Cas9 targeting Ttc30a mimics ciliary chondrodysplasia with polycystic kidney disease

Authors:
Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.27.400994
Epub:
Not Epub
Abstract:
Skeletal ciliopathies (e.g. Jeune syndrome, short rib polydactyly syndrome, Sensenbrenner syndrome) are frequently associated...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.27.400994v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS. CRISPR/Cas9 targeting Ttc30a mimics ciliary chondrodysplasia with polycystic kidney disease. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.27.400994 .

Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis

Authors:
Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.23.394171
Epub:
Not Epub
Abstract:
Zygotic genome activation (ZGA) initiates regionalized transcription responsible for the acquisition of distinct cellular...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.23.394171v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S. Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.23.394171 .

Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation

Authors:
Huebner RJ, Malmi-Kakkada AN, Sarikaya S, Weng S, Thirumalai D, Wallingford JB
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.11.944033
Epub:
Not Epub
Abstract:
Morphogenesis is governed by the interplay of molecular signals and mechanical forces across multiple length scales. The last...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.11.944033v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Huebner RJ, Malmi-Kakkada AN, Sarikaya S, Weng S, Thirumalai D, Wallingford JB. Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.11.944033.

In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces

Authors:
Dur AH, Tang T, Viviano S, Sekuri A, Willsey HR, Tagare HD, Kahle KT, Deniz E
Citation:
Fluids Barriers CNS. 2020;17(1):72. doi:10.1186/s12987-020-00234-z
Epub:
Not Epub
Abstract:
Hydrocephalus, the pathological expansion of the cerebrospinal fluid (CSF)-filled cerebral ventricles, is a common, deadly...
Link:
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-020-00234-z
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Dur AH, Tang T, Viviano S, Sekuri A, Willsey HR, Tagare HD, Kahle KT, Deniz E. In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces. Fluids Barriers CNS. 2020;17(1):72. doi:10.1186/s12987-020-00234-z.

Chemical Modulators of Fibrinogen Production and Their Impact on Venous Thrombosis

Authors:
Vilar R, Lukowski SW, Garieri M, Di Sanza C, Neerman-Arbez M, Fish RJ
Citation:
Thromb Haemost. 2020 Dec 10. doi: 10.1055/s-0040-1718414. Online ahead of print
Epub:
Yes
Abstract:
Thrombosis is a leading cause of morbidity and mortality. Fibrinogen, the soluble substrate for fibrin-based clotting, has a...
Link:
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1718414
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vilar R, Lukowski SW, Garieri M, Di Sanza C, Neerman-Arbez M, Fish RJ. Chemical Modulators of Fibrinogen Production and Their Impact on Venous Thrombosis. Thromb Haemost. 2020 Dec 10. doi: 10.1055/s-0040-1718414. Online ahead of print.

Pages