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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface

Authors:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J
Citation:
ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print]
Epub:
Yes
Abstract:
Monoclonal antibody therapy has offered treatment benefits. Nonetheless, lack of efficacy still exists, partially because...
Link:
https://pubs.acs.org/doi/10.1021/acsnano.9b04868
Organism or Cell Type:
mice
Citation Extract:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J. Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface. ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print].

Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis

Authors:
Havrilak JA, Layden MJ
Citation:
Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2
Epub:
Not Epub
Abstract:
The cnidarian sea anemone Nematostella vectensis has grown in popularity as a model system to complement the ongoing work in...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-9732-9_2
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Havrilak JA, Layden MJ. Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis. Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2.

Towards the identification of causal genes for age-related macular degeneration

Authors:
Cheng F-F, Zhuang Y-Y, Wen X-R, Xue A, Yang J, Jin Z-B
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/778613
Epub:
Not Epub
Abstract:
Age-related macular degeneration (AMD) is a leading cause of visual impairment in ageing populations and has no radical...
Link:
https://www.biorxiv.org/content/10.1101/778613v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng F-F, Zhuang Y-Y, Wen X-R, Xue A, Yang J, Jin Z-B. Towards the identification of causal genes for age-related macular degeneration. bioRxiv. 2019;[preprint] doi:10.1101/778613 .

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation

Authors:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM
Citation:
bioRxiv. 2019[preprint] doi:10.1101/777664
Epub:
Not Epub
Abstract:
The trachea and esophagus arise from the separation of a common foregut tube during early fetal development. Mutations in key...
Link:
https://www.biorxiv.org/content/10.1101/777664v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM. Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation. bioRxiv. 2019[preprint] doi:10.1101/777664 .

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063
Epub:
Yes
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31118-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063.

lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish

Authors:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X
Citation:
J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237
Epub:
Yes
Abstract:
lncrps25 is an intergenic long noncoding RNA (lncRNA), which is location close to rps25 (ribosomal protein S25) gene, is...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29237
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X. lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish. J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237.

Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b

Authors:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y
Citation:
PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print]
Epub:
Yes
Abstract:
During vertebrate early embryogenesis, the ventral development is directed by the ventral-to-dorsal activity gradient of the...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008306
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print].

Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis

Authors:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U
Citation:
Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print]
Epub:
Yes
Abstract:
Morphogenesis is a shape-building process during development of multicellular organisms. During this process the establishment...
Link:
https://dev.biologists.org/content/early/2019/09/19/dev.174623.long
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U. Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis. Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print].

Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner

Authors:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF
Citation:
Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Insufficient delivery of oligonucleotides to muscle and heart remains a barrier for clinical implementation of antisense...
Link:
http://www.sciencedirect.com/science/article/pii/S2162253119302598
Delivery Method:
peptide-linked
Organism or Cell Type:
mice mdx
Citation Extract:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF. Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print].

The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice

Authors:
Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A
Citation:
bioRxiv. 2019;[preprint] doi: 10.1101/730010
Epub:
Not Epub
Abstract:
The development of the gut from endodermal tissue to an organ with multiple distinct structures and functions occurs over a...
Link:
https://www.biorxiv.org/content/10.1101/730010v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A. The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice. bioRxiv. 2019;[preprint] doi: 10.1101/730010 .

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