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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Draxin alters laminin expression during basement membrane reorganization to control cranial neural crest EMT

Authors:
Hutchins EJ, Bronner ME
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/407882
Epub:
Not Epub
Abstract:
Premigratory neural crest cells arise within the dorsal neural tube and subsequently undergo an epithelial-to-mesenchymal...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hutchins EJ, Bronner ME. Draxin alters laminin expression during basement membrane reorganization to control cranial neural crest EMT. bioRxive. 2018;[Preprint] doi:10.1101/407882.

Bacterial T6SS Effector EvpP Inhibits Neutrophil Recruitment via Jnk-Caspy Inflammasome Signaling In vivo

Authors:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/453076
Epub:
Not Epub
Abstract:
The type VI secretion system (T6SS) comprises dynamic complex bacterial contractile nanomachines and is used by many bacteria...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q. Bacterial T6SS Effector EvpP Inhibits Neutrophil Recruitment via Jnk-Caspy Inflammasome Signaling In vivo. bioRxive. 2018;[Preprint] doi:10.1101/453076.

Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway

Authors:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F
Citation:
bioRxiv. 2018;[Preprint] doi:10.1101/459263
Epub:
Not Epub
Abstract:
Alternative splicing (AS) strongly increases proteome diversity and functionality in eukaryotic cells. Protein secretion is a...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture:HEK293T
Citation Extract:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F. Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway. bioRxiv. 2018;[Preprint] doi:10.1101/459263 .

The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development

Authors:
Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC
Citation:
Sci Rep. 2018 Oct 30;8(1):16029. doi:10.1038/s41598-018-34038-x
Epub:
Not Epub
Abstract:
The molecular events driving specification of the kidney have been well characterized. However, how the initial kidney field...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC. The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development. Sci Rep. 2018 Oct 30;8(1):16029. doi:10.1038/s41598-018-34038-x.

Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43

Authors:
Bhattacharya S, Gargiulo D, Iovine MK
Citation:
Development. 2018;[Epub ahead of print] doi: 10.1242/dev.166975
Epub:
Yes
Abstract:
The correct positioning of joints in the vertebrate skeleton is not well understood. Mutations in connexin43 (cx43) cause the...
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattacharya S, Gargiulo D, Iovine MK. Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development. 2018;[Epub ahead of print] doi: 10.1242/dev.166975.

WDR5 regulates left-right patterning via chromatin dependent and independent functions

Authors:
Kulkarni SS, Khokha MF
Citation:
Development. 2018;[Epub ahead of print] doi: 10.1242/dev.159889
Epub:
Yes
Abstract:
Congenital heart disease (CHD) is a major cause of infant mortality and morbidity, yet the genetic causes and mechanisms remain...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kulkarni SS, Khokha MF. WDR5 regulates left-right patterning via chromatin dependent and independent functions. Development. 2018;[Epub ahead of print] doi: 10.1242/dev.159889.

Antisense oligonucleotides modulate dopa decarboxylase function in aromatic l-amino acid decarboxylase deficiency

Authors:
Tsai CR, Lee HF, Chi CS, Yang MT, Hsu CC
Citation:
Hum Mutat. 2018 Sep 27. doi: 10.1002/humu.23659. [Epub ahead of print]
Epub:
Yes
Abstract:
Aromatic l-amino acid decarboxylase deficiency (AADCD), attributed to mutations in the dopa decarboxylase (DDC) gene, is a rare...
Organism or Cell Type:
cell culture: primary human lymphoblastoid cells
Citation Extract:
Tsai CR, Lee HF, Chi CS, Yang MT, Hsu CC. Antisense oligonucleotides modulate dopa decarboxylase function in aromatic l-amino acid decarboxylase deficiency. Hum Mutat. 2018 Sep 27. doi: 10.1002/humu.23659. [Epub ahead of print].

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

Authors:
Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH
Citation:
J Biol Chem. 2018 Dec 21;293(51):19797-19811. doi: 10.1074/jbc.RA118.002742. Epub 2018 Oct 26.
Epub:
Not Epub
Abstract:
Erythropoietin (EPO) signaling is critical to many processes essential to terminal erythropoiesis. Despite the centrality of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. J Biol Chem. 2018 Dec 21;293(51):19797-19811. doi: 10.1074/jbc.RA118.002742. Epub 2018 Oct 26..

Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis

Authors:
Nguyen AL, Drutovic D, Vazquez BN, El Yakoubi W, Gentilello AS, Malumbres M, Solc P, Schindler K
Citation:
Curr Biol. 2018;28 [Epub ahead of print] doi:10.1016/j.cub.2018.08.052
Epub:
Yes
Abstract:
Errors in chromosome segregation during female meiosis I occur frequently, and aneuploid embryos account for 1/3 of all...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Nguyen AL, Drutovic D, Vazquez BN, El Yakoubi W, Gentilello AS, Malumbres M, Solc P, Schindler K. Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis. Curr Biol. 2018;28 [Epub ahead of print] doi:10.1016/j.cub.2018.08.052.

Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development

Authors:
Gibb N, Lazic S, Yuan X, Deshwar AR, Leslie M, Wilson MD, Scott IC
Citation:
Development. 2018;[Epub ahead of print] doi:10.1242/dev.167510
Epub:
Yes
Abstract:
A key event in heart development is the timely addition of cardiac progenitor cells, defects in which can lead to congenital...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibb N, Lazic S, Yuan X, Deshwar AR, Leslie M, Wilson MD, Scott IC. Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development. Development. 2018;[Epub ahead of print] doi:10.1242/dev.167510 .

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