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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
tbx5 and tbx15 mediate zebrafish posterior lateral line migration and development via a negative feedback loop
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Citation:
bioRxive. 2018;[preprint]:452797 doi:10.1101/452797 Epub:
Not Epub Abstract:
The zebrafish posterior lateral line (pLL) is a mechanosensory organ enabling detection of movement in the aqueous environment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Whitehurst HR, Gallardo VE, Burgess SM. tbx5 and tbx15 mediate zebrafish posterior lateral line migration and development via a negative feedback loop. bioRxive. 2018;[preprint]:452797 doi:10.1101/452797 . |
Increased dynamin expression precedes proteinuria in glomerular disease
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Citation:
J Pathol. 2018 Oct 22. doi: 10.1002/path.5181. [Epub ahead of print] Epub:
Yes Abstract:
Dynamin plays an essential role in maintaining the structure and function of the glomerular filtration barrier. Specifically,... Citation Extract: Khalil R, Koop K, Kreutz R, Spaink HP, Hogendoorn PCW, Bruijn JA, Baelde HJ. Increased dynamin expression precedes proteinuria in glomerular disease. J Pathol. 2018 Oct 22. doi: 10.1002/path.5181. [Epub ahead of print]. |
A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-β oligomers
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Citation:
EMBO J. 2018 Oct 22. pii: e100241. doi: 10.15252/embj.2018100241. [Epub ahead of print] Epub:
Yes Abstract:
The mechanisms of mitochondrial dysfunction in Alzheimer's disease are incompletely understood. Using two‐photon... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse cortical neurons Citation Extract: Norambuena A, Wallrabe H, Cao R, Wang DB, Silva A, Svindrych Z, Periasamy A, Hu S, Tanzi RE, Kim DY, Bloom GS. A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-β oligomers. EMBO J. 2018 Oct 22. pii: e100241. doi: 10.15252/embj.2018100241. [Epub ahead of print]. |
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development
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Citation:
PNAS USA. 2018;[Epub ahead of print] doi:10.1073/pnas.1811624115 Epub:
Yes Abstract:
Codevelopment of the lungs and heart underlies key evolutionary innovations in the transition to terrestrial life. Cardiac... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS-K, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP. Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. PNAS USA. 2018;[Epub ahead of print] doi:10.1073/pnas.1811624115. |
K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay
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Citation:
Oncogene. 2018 Oct 22. doi: 10.1038/s41388-018-0542-3. [Epub ahead of print] Epub:
Yes Abstract:
The point mutation that substitutes lysine with arginine at position 120 of human p53 has been characterized as a missense... Organism or Cell Type:
cell culture: human engineered iPSC line Citation Extract: Lee SY, Park JH, Jeong S, Kim BY, Kang YK, Xu Y, Chung SK. K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay. Oncogene. 2018 Oct 22. doi: 10.1038/s41388-018-0542-3. [Epub ahead of print]. |
Electroporation and in vitro culture of early rabbit embryos
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Citation:
Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.06.012 Epub:
Yes Abstract:
The phenomenal migratory and differentiation capacity of neural crest cells has been well established across model organisms.... Delivery Method:
electroporation Organism or Cell Type:
Oryctolagus cuniculus (rabbit) Citation Extract: Betters E, Charney RM, García-Castro MI. Electroporation and in vitro culture of early rabbit embryos. Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.06.012. |
Efficacy of multi-exon skipping treatment in Duchenne muscular dystrophy dog model neonates
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Citation:
Molec Therapy. 2018;[Epub ahead of print] doi:10.1016/j.ymthe.2018.10.011 Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations in DMD, which codes for dystrophin. Because the progressive and... Delivery Method:
i.v. infusion Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Lim KRQ, Echigoya Y, Nagata T, Kuraoka M, Kobayashi M, Aoki Y, Partridge T, Maruyama R, Takeda S, Yokota T. Efficacy of multi-exon skipping treatment in Duchenne muscular dystrophy dog model neonates. Molec Therapy. 2018;[Epub ahead of print] doi:10.1016/j.ymthe.2018.10.011. |
Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing
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Citation:
bioRxiv. 2018:446773[Preprint] doi:10.1101/446773 Epub:
Not Epub Abstract:
Oligonucleotides and nucleic acid analogues that alter gene expression are showing therapeutic promise for selected human... Organism or Cell Type:
cell culture Citation Extract: Flynn LL, Li R, Aung-Htut MT, Pitout IL, Cooper J, Hubbard A, Griffiths L, Bond C, Wilton SD, Fox AH, Fletcher S. Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing. bioRxiv. 2018:446773[Preprint] doi:10.1101/446773 . |
NADPH-Oxidase-derived reactive oxygen species are required for cytoskeletal organization, proper localization of E-cadherin and cell motility during zebrafish epiboly
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Citation:
Free Radic Biol Med. 2018 Oct 17. pii: S0891-5849(18)32192-0. doi: 10.1016/j.freeradbiomed.2018.10.416. [Epub ahead of print] Epub:
Not Epub Abstract:
Cell movements are essential for morphogenesis during animal development. Epiboly is the first morphogenetic process in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mendieta-Serrano MA, Mendez-Cruz FJ, Antúnez-Mojica M, Schnabel D, Alvarez L, Cárdenas L, Lomelí H, Ruiz-Santiesteban JA, Salas-Vidal E. NADPH-Oxidase-derived reactive oxygen species are required for cytoskeletal organization, proper localization of E-cadherin and cell motility during zebrafish epiboly. Free Radic Biol Med. 2018 Oct 17. pii: S0891-5849(18)32192-0. doi: 10.1016/j.freeradbiomed.2018.10.416. [Epub ahead of print]. |
Basal epithelial tissue folding is mediated by differential regulation of microtubules
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Citation:
Development. 2018 Oct 17. pii: dev.167031. doi: 10.1242/dev.167031. [Epub ahead of print] Epub:
Yes Abstract:
The folding of epithelial tissues is critical for development of three-dimensional structure and function. Understanding this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Visetsouk MR, Falat EJ, Garde RJ, Wendlick JL, Gutzman JH. Basal epithelial tissue folding is mediated by differential regulation of microtubules. Development. 2018 Oct 17. pii: dev.167031. doi: 10.1242/dev.167031. [Epub ahead of print]. |