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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

MicroRNA-223 Suppresses the Canonical NF-kB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation

Authors:
Zhou W, Pal AS, Hsu AY-H, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q
Citation:
Cell Rep. 2018;22:1810-1823. doi:10.1016/j.celrep.2018.01.058
Epub:
Not Epub
Abstract:
MicroRNA-223 is known as a myeloid-enriched anti-inflammatory microRNA that is dysregulated innumerous inflammatory conditions...
Link:
http://www.cell.com/cell-reports/pdf/S2211-1247(18)30107-4.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou W, Pal AS, Hsu AY-H, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q. MicroRNA-223 Suppresses the Canonical NF-kB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Cell Rep. 2018;22:1810-1823. doi:10.1016/j.celrep.2018.01.058.

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin

Authors:
Ackerman SD, Luo R, Poitelon Y, Mogha A, Harty BL, D'Rozario M, Sanchez NE, Lakkaraju AKK, Gamble P, Li J, Qu J, MacEwan MR, Ray WZ, Aguzzi A, Feltri ML, Piao X, Monk KR
Citation:
J Exp Med. 2018 Jan 24. pii: jem.20161714. doi: 10.1084/jem.20161714. [Epub ahead of print]
Epub:
Yes
Abstract:
Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS...
Link:
http://jem.rupress.org/content/early/2018/01/24/jem.20161714
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ackerman SD, Luo R, Poitelon Y, Mogha A, Harty BL, D'Rozario M, Sanchez NE, Lakkaraju AKK, Gamble P, Li J, Qu J, MacEwan MR, Ray WZ, Aguzzi A, Feltri ML, Piao X, Monk KR. GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018 Jan 24. pii: jem.20161714. doi: 10.1084/jem.20161714. [Epub ahead of print].

Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish

Authors:
Zhong Y, Ye Q, Chen C, Wang M, Wang H
Citation:
Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky101
Epub:
Yes
Abstract:
EZH2 is a subunit of polycomb repressive complex 2 (PRC2) that silences gene transcription via H3K27me3 and was shown to be...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky101/4852815
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Y, Ye Q, Chen C, Wang M, Wang H. Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish. Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky101.

Loss of function mutations in EPHB4 are responsible for vein of Galen aneurysmal malformation

Authors:
Vivanti A, Ozanne A, Grondin C, Saliou G, Quevarec L, Maurey H, Aubourg P, Benachi A, Gut M, Gut I, Martinovic J, Sénat MV, Tawk M, Melki J
Citation:
Brain. 2018;[Epub ahead of print] doi:10.1093/brain/awy020
Epub:
Yes
Abstract:
Vein of Galen aneurysmal malformation is a congenital anomaly of the cerebral vasculature representing 30% of all paediatric...
Link:
https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awy020/4850501
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vivanti A, Ozanne A, Grondin C, Saliou G, Quevarec L, Maurey H, Aubourg P, Benachi A, Gut M, Gut I, Martinovic J, Sénat MV, Tawk M, Melki J. Loss of function mutations in EPHB4 are responsible for vein of Galen aneurysmal malformation. Brain. 2018;[Epub ahead of print] doi:10.1093/brain/awy020.

Sema3a plays a role in the pathogenesis of CHARGE syndrome

Authors:
Ufartes R, Schwenty-Lara J, Freese L, Neuhofer C, Möller J, Wehner P, van Ravenswaaij-Arts CMA, Wong MTY Schanze I, Tzschach A, Bartsch O, Borchers A, Pauli S
Citation:
Hum Mol Genet. 2018;[Epub] doi:10.1093/hmg/ddy045
Epub:
Yes
Abstract:
CHARGE syndrome is an autosomal dominant malformation disorder caused by heterozygous loss of function mutations in the...
Link:
https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddy045/4844880
Organism or Cell Type:
Xenopus
Citation Extract:
Ufartes R, Schwenty-Lara J, Freese L, Neuhofer C, Möller J, Wehner P, van Ravenswaaij-Arts CMA, Wong MTY Schanze I, Tzschach A, Bartsch O, Borchers A, Pauli S. Sema3a plays a role in the pathogenesis of CHARGE syndrome. Hum Mol Genet. 2018;[Epub] doi:10.1093/hmg/ddy045.

Loss-of-Function Mutations in UNC45A Cause a Syndrome Associating Cholestasis, Diarrhea, Impaired Hearing, and Bone Fragility

Authors:
Maudinas R, Mazodier K, Rimet Y, Rivière J-B, Roquelaure B, Sigaudy S, Stephenne X, Thauvin-Robinet C, Thevenon J, Sarles J, Levy N, Badens C, Goulet O, Hugot J-P, Katsanis N, Faivre L, Fabre A
Citation:
Am J Hum Genet. 2018;[Epub ahead of print] doi:doi.org/10.1016/j.ajhg.2018.01.009
Epub:
Yes
Abstract:
Despite the rapid discovery of genes for rare genetic disorders, we continue to encounter individuals presenting with syndromic...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(18)30009-0
Organism or Cell Type:
zebrafish
Citation Extract:
Maudinas R, Mazodier K, Rimet Y, Rivière J-B, Roquelaure B, Sigaudy S, Stephenne X, Thauvin-Robinet C, Thevenon J, Sarles J, Levy N, Badens C, Goulet O, Hugot J-P, Katsanis N, Faivre L, Fabre A. Loss-of-Function Mutations in UNC45A Cause a Syndrome Associating Cholestasis, Diarrhea, Impaired Hearing, and Bone Fragility. Am J Hum Genet. 2018;[Epub ahead of print] doi:doi.org/10.1016/j.ajhg.2018.01.009.

An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System

Authors:
Di Donato V, De Santis F, Albadri S, Auer TO, Duroure K, Charpentier M, Concordet J-P, Gebhardt C, Del Bene F
Citation:
Neuron. 2018;[Epub ahead of print] doi:10.1016/j.neuron.2018.01.030
Epub:
Yes
Abstract:
A conserved organizational and functional principle of neural networks is the segregation of axon-dendritic synaptic...
Link:
http://www.cell.com/neuron/fulltext/S0896-6273(18)30055-2
Organism or Cell Type:
zebrafish
Citation Extract:
Di Donato V, De Santis F, Albadri S, Auer TO, Duroure K, Charpentier M, Concordet J-P, Gebhardt C, Del Bene F. An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System. Neuron. 2018;[Epub ahead of print] doi:10.1016/j.neuron.2018.01.030.

Effects of long-term treatment with eteplirsen on cardiac function

Authors:
Cripe L, Colan S. Eliopoulos H, Moody S, Mendell J
Citation:
Neuromusc Disord. 2017;27(suppl 2):S114 doi:10.1016/j.nmd.2017.06.083
Epub:
Not Epub
Link:
http://www.nmd-journal.com/article/S0960-8966(17)30656-9/abstract
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Cripe L, Colan S. Eliopoulos H, Moody S, Mendell J. Effects of long-term treatment with eteplirsen on cardiac function. Neuromusc Disord. 2017;27(suppl 2):S114 doi:10.1016/j.nmd.2017.06.083.

NHLRC2 variants identified in patients with fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA): characterisation of a novel cerebropulmonary disease

Authors:
Uusimaa J, Kaarteenaho R, Paakkola T, Tuominen H, Karjalainen MK, Nadaf J,Varilo T, Uusi-Mäkelä M, Suo-Palosaari M, Pietilä I, Hiltunen AE, Ruddock L, Alanen H, Biterova E, Miinalainen I, Salminen A, Soininen R, Manninen A, Sormunen R, Kaakinen M, Vuolteenaho R, Herva R, Vieira P, Teija Dunder T, Kokkonen H, Moilanen JS, Rantala H, Nogee LM, Majewski J, Rämet M, Hallman M, Hinttala R
Citation:
Acta Neuropath. 2018;[Epub ahead of print] doi:10.1007/s00401-018-1817-z
Epub:
Not Epub
Abstract:
A novel multi-organ disease that is fatal in early childhood was identified in three patients from two non-consanguineous...
Link:
https://link.springer.com/article/10.1007%2Fs00401-018-1817-z
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Uusimaa J, Kaarteenaho R, Paakkola T, Tuominen H, Karjalainen MK, Nadaf J,Varilo T, Uusi-Mäkelä M, Suo-Palosaari M, Pietilä I, Hiltunen AE, Ruddock L, Alanen H, Biterova E, Miinalainen I, Salminen A, Soininen R, Manninen A, Sormunen R, Kaakinen M, Vuolteenaho R, Herva R, Vieira P, Teija Dunder T, Kokkonen H, Moilanen JS, Rantala H, Nogee LM, Majewski J, Rämet M, Hallman M, Hinttala R. NHLRC2 variants identified in patients with fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA): characterisation of a novel cerebropulmonary disease. Acta Neuropath. 2018;[Epub ahead of print] doi:10.1007/s00401-018-1817-z.

Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis

Authors:
Donat S, Lourenço M, Paolini A, Otten C, Renz M, Abdelilah-Seyfried S
Citation:
Elife. 2018 Feb 1;7. pii: e28939. doi: 10.7554/eLife.28939
Epub:
Not Epub
Abstract:
Endothelial cells respond to different levels of fluid shear stress through adaptations of their mechanosensitivity. Currently...
Link:
https://elifesciences.org/articles/28939
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donat S, Lourenço M, Paolini A, Otten C, Renz M, Abdelilah-Seyfried S. Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis. Elife. 2018 Feb 1;7. pii: e28939. doi: 10.7554/eLife.28939.

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