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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy

Authors:
Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri M, Takashima S, Kitakaze M, Hayashi K
Citation:
Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y
Epub:
Not Epub
Abstract:
The pathogenesis of heart failure associated with dilated cardiomyopathy (DCM) may result in part from adenosine triphosphate (...
Link:
https://www.nature.com/articles/s41598-017-17572-y correction: https://www.nature.com/articles/s41598-018-26012-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri M, Takashima S, Kitakaze M, Hayashi K. Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy. Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y.

In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw

Authors:
McGurk PD, Swartz ME, Chen JW, Galloway JL, Eberhart JK
Citation:
PLoS Genet. 2017;13(12):e1007112. doi:10.1371/journal.pgen.1007112
Epub:
Not Epub
Abstract:
Integrated development of diverse tissues gives rise to a functional, mobile vertebrate musculoskeletal system. However, the...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007112
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGurk PD, Swartz ME, Chen JW, Galloway JL, Eberhart JK. In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw. PLoS Genet. 2017;13(12):e1007112. doi:10.1371/journal.pgen.1007112.

A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure

Authors:
Hung CY, Volkmar B, Baker JD, Bauer JW, Gussoni E, Hainzl S, Klausegger A, Lorenzo J, Mihalek I, Rittinger O, Tekin M, Dallman JE, Bodamer OA
Citation:
PLoS ONE. 2017;12(12):e0189324. doi:10.1371/journal.pone.0189324
Epub:
Not Epub
Abstract:
Primordial growth failure has been linked to defects in the biology of cell division and replication. The complex processes...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189324
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung CY, Volkmar B, Baker JD, Bauer JW, Gussoni E, Hainzl S, Klausegger A, Lorenzo J, Mihalek I, Rittinger O, Tekin M, Dallman JE, Bodamer OA. A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure. PLoS ONE. 2017;12(12):e0189324. doi:10.1371/journal.pone.0189324.

EphA7 regulates claudin6 and pronephros development in Xenopus

Authors:
Sun J, Wang X, Shi Y, Li J, Li C, Shi Z, Chen Y, Mao B
Citation:
Biochem Biophys Res Commun. 2017 Dec 6. pii: S0006-291X(17)32412-9. doi: 10.1016/j.bbrc.2017.12.027. [Epub ahead of print]
Epub:
Yes
Abstract:
Eph/ephrin molecules are widely expressed during embryonic development, and function in a variety of developmental processes....
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X17324129
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sun J, Wang X, Shi Y, Li J, Li C, Shi Z, Chen Y, Mao B. EphA7 regulates claudin6 and pronephros development in Xenopus. Biochem Biophys Res Commun. 2017 Dec 6. pii: S0006-291X(17)32412-9. doi: 10.1016/j.bbrc.2017.12.027. [Epub ahead of print].

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase

Authors:
Patrikainen MS, Tolvanen MEE, Aspatwar A, Barker HR, Ortutay C, Jänis J, Laitaoja M, Hytönen VP, Azizi L, Manandhar P, Jáger E, Vullo D, Kukkurainen S, Hilvo M, Supuran CT, Parkkila S
Citation:
PeerJ. 2017;5:e4128 doi:10.7717/peerj.4128
Epub:
Not Epub
Abstract:
Background: Carbonic anhydrases (CAs) are ubiquitous, essential enzymes which catalyze the conversion of carbon dioxide and...
Link:
https://peerj.com/articles/4128/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patrikainen MS, Tolvanen MEE, Aspatwar A, Barker HR, Ortutay C, Jänis J, Laitaoja M, Hytönen VP, Azizi L, Manandhar P, Jáger E, Vullo D, Kukkurainen S, Hilvo M, Supuran CT, Parkkila S. Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase. PeerJ. 2017;5:e4128 doi:10.7717/peerj.4128.

Nodal patterning without Lefty inhibitory feedback is functional but fragile

Authors:
Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF
Citation:
Elife. 2017 Dec 7;6. pii: e28785. doi: 10.7554/eLife.28785
Epub:
Not Epub
Abstract:
Developmental signaling pathways often activate their own inhibitors. Such inhibitory feedback has been suggested to restrict...
Link:
https://elifesciences.org/articles/28785
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF. Nodal patterning without Lefty inhibitory feedback is functional but fragile. Elife. 2017 Dec 7;6. pii: e28785. doi: 10.7554/eLife.28785.

Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus

Authors:
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M
Citation:
Nat Commun. 2017 Dec 7;8(1):1973. doi: 10.1038/s41467-017-02076-0
Epub:
Not Epub
Abstract:
Wnt proteins direct embryonic patterning, but the regulatory basis of their distribution and signal reception remain unclear....
Link:
https://www.nature.com/articles/s41467-017-02076-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M. Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus. Nat Commun. 2017 Dec 7;8(1):1973. doi: 10.1038/s41467-017-02076-0.

Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo

Authors:
Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB
Citation:
Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003
Epub:
Not Epub
Abstract:
Interactions between tumor cells and tumor-associated macrophages play critical roles in the initiation of tumor cell motility...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807(17)30907-3
Citation Extract:
Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB. Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo. Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003.

Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency

Authors:
Pena IA, Roussel Y, Daniel K, Mongeon K, Johnstone D, Weinschutz Mendes H, Bosma M, Saxena V, Lepage N, Chakraborty P, Dyment DA, van Karnebeek CDM, Verhoeven-Duif N, Bui TV, Boycott KM, Ekker M, MacKenzie A
Citation:
Genetics. 2017 Dec;207(4):1501-1518. doi: 10.1534/genetics.117.300137. Epub 2017 Oct 23
Epub:
Not Epub
Abstract:
Pyridoxine-dependent epilepsy (PDE) is a rare disease characterized by mutations in the lysine degradation gene ALDH7A1 leading...
Link:
http://www.genetics.org/content/207/4/1501
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pena IA, Roussel Y, Daniel K, Mongeon K, Johnstone D, Weinschutz Mendes H, Bosma M, Saxena V, Lepage N, Chakraborty P, Dyment DA, van Karnebeek CDM, Verhoeven-Duif N, Bui TV, Boycott KM, Ekker M, MacKenzie A. Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency. Genetics. 2017 Dec;207(4):1501-1518. doi: 10.1534/genetics.117.300137. Epub 2017 Oct 23.

The exon 45 skipping therapy of induced pluripotent stem cells derived cardiomyocyte from the DMD patient with exon 46-55 deletion

Authors:
Sato M, Miyazaki D, Shiba Y, Echigoya Y, Yokota T, Aoki Y, Takeda S, Nakamura A
Citation:
J Neurol Sci. 2017;381suppl:142. doi:10.1016/j.jns.2017.08.420
Epub:
Not Epub
Abstract:
No abstract available
Link:
http://www.jns-journal.com/article/S0022-510X(17)30917-6/fulltext
Organism or Cell Type:
cell culture: primary iPSC DMD cells differentiated to cardiomyocytes
Citation Extract:
Sato M, Miyazaki D, Shiba Y, Echigoya Y, Yokota T, Aoki Y, Takeda S, Nakamura A. The exon 45 skipping therapy of induced pluripotent stem cells derived cardiomyocyte from the DMD patient with exon 46-55 deletion. J Neurol Sci. 2017;381suppl:142. doi:10.1016/j.jns.2017.08.420.

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