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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12370 scientific papers returned from the database with the search filters currently being used below.
There are 12370 scientific papers returned from the database with the search filters currently being used below.
Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation
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Citation:
Dis Model Mech. 2017 Oct 9. pii: dmm.026922. doi: 10.1242/dmm.026922. [Epub ahead of print] Epub:
Yes Abstract:
Mutations in MECP2 cause Rett syndrome, a severe neurological disorder with autism-like features. Duplication of MECP2 also... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D. Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. Dis Model Mech. 2017 Oct 9. pii: dmm.026922. doi: 10.1242/dmm.026922. [Epub ahead of print]. |
Notch-mediated lateral inhibition is an evolutionarily conserved mechanism patterning the ectoderm in echinoids
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Citation:
Dev Genes Evol. 2017;{Epub ahead or print] doi:10.1007/s00427-017-0599-y Epub:
Yes Abstract:
Notch signaling is a crucial cog in early development of euechinoid sea urchins, specifying both non-skeletogenic mesodermal... Delivery Method:
microinjection Organism or Cell Type:
Eucidaris tribuloides (sea urchin) Citation Extract: Erkenbrack EM. Notch-mediated lateral inhibition is an evolutionarily conserved mechanism patterning the ectoderm in echinoids. Dev Genes Evol. 2017;{Epub ahead or print] doi:10.1007/s00427-017-0599-y. |
Single-cell transcriptome analysis of avian neural crest migration reveals signatures of invasion and molecular transitions
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Citation:
Elife. 2017 Dec 4;6. pii: e28415. doi: 10.7554/eLife.28415 Epub:
Not Epub Abstract:
Neural crest cells migrate throughout the embryo, but how cells move in a directed and collective manner has remained unclear.... Delivery Method:
Endo-Porter (cultures), injection then electroporation (embryos) Organism or Cell Type:
cell culture: LMH cell line, Gallus gallus (chick) Citation Extract: Morrison JA, McLennan R, Wolfe LA, Gogol MM, Meier S, McKinney MC, Teddy JM, Holmes L, Semerad CL, Box AC, Li H, Hall KE, Perera AG, Kulesa PM. Single-cell transcriptome analysis of avian neural crest migration reveals signatures of invasion and molecular transitions. Elife. 2017 Dec 4;6. pii: e28415. doi: 10.7554/eLife.28415. |
Activation of Lysophosphatidic Acid Receptor 3 Inhibits Megakaryopoiesis in Human Hematopoietic Stem Cells and Zebrafish
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Citation:
Stem Cells Dev. 2017 Dec 14. doi: 10.1089/scd.2017.0190. [Epub ahead of print] Epub:
Yes Abstract:
Lysophosphatidic acid (LPA) is a membrane-derived lysophospholipid that exists in the plasma and platelets. It exerts its... Organism or Cell Type:
zebrafish Citation Extract: Lin KH, Li MW, Chang YC, Lin YN, Ho YH, Weng WC, Huang CJ, Chang BE, Yao CL, Lee H. Activation of Lysophosphatidic Acid Receptor 3 Inhibits Megakaryopoiesis in Human Hematopoietic Stem Cells and Zebrafish. Stem Cells Dev. 2017 Dec 14. doi: 10.1089/scd.2017.0190. [Epub ahead of print]. |
ABIN-1 negatively Regulates μ-opioid Receptor Function
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Citation:
Mol Pharmacol. 2017 Dec 13. pii: mol.117.109009. doi: 10.1124/mol.117.109009. [Epub ahead of print] Epub:
Yes Abstract:
The μ-opioid receptor (MOR) is a Gi/o protein-coupled receptor that mediates analgesic, euphoric, and reward effects. Using a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou P, Jiang J, Yan H, Li Y, Zhao J, Wang X, Su R, Gong Z. ABIN-1 negatively Regulates μ-opioid Receptor Function. Mol Pharmacol. 2017 Dec 13. pii: mol.117.109009. doi: 10.1124/mol.117.109009. [Epub ahead of print]. |
Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension
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Citation:
Sci Rep. 2017;7:17607. doi:10.1038/s41598-017-17898-7 Epub:
Not Epub Abstract:
The grainyhead-like (grhl) transcription factors play crucial roles in craniofacial development, epithelial morphogenesis,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Miles LB, Darido C, Kaslin J, Heath JK, Jane SM, Dworkin S. Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension. Sci Rep. 2017;7:17607. doi:10.1038/s41598-017-17898-7. |
Tissue-Resident TSP1-CD47 Signaling Promotes Sickle Cell-Associated Arterial Vasculopathy and Pulmonary Hypertension
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Citation:
Blood, 2017;130(Suppl 1):957 Epub:
Not Epub Abstract:
Pulmonary hypertension (PH) is a chronic pulmonary complication of sickle cell disease (SCD) and a leading cause of death in... Delivery Method:
i.p. injection Organism or Cell Type:
mice Citation Extract: Novelli EM, Ihrig LL, Knupp HE, Rogers NM, Yao M, Huang X, Baust J, Meijles D, St Croix CM, Ross MA, Pagano PJ, Champion HC, Miles G, Potoka KP, Gladwin MT, Isenberg JS. Tissue-Resident TSP1-CD47 Signaling Promotes Sickle Cell-Associated Arterial Vasculopathy and Pulmonary Hypertension. Blood, 2017;130(Suppl 1):957. |
Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis
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Citation:
Dev Biol. 2017 Dec 8. pii: S0012-1606(17)30430-X. doi: 10.1016/j.ydbio.2017.11.017. [Epub ahead of print] Epub:
Yes Abstract:
The transcription factors GATA4, GATA5 and GATA6 are important regulators of heart muscle differentiation (cardiomyogenesis),... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S. Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis. Dev Biol. 2017 Dec 8. pii: S0012-1606(17)30430-X. doi: 10.1016/j.ydbio.2017.11.017. [Epub ahead of print]. |
Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis
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Citation:
PLoS One. 2017 Dec 12;12(12):e0189010. doi: 10.1371/journal.pone.0189010. eCollection 2017 Epub:
Not Epub Abstract:
Remodeling of the primitive vasculature is necessary for the formation of a complex branched vascular architecture. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Singh BN, Tahara N, Kawakami Y, Das S, Koyano-Nakagawa N, Gong W, Garry MG, Garry DJ. Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis. PLoS One. 2017 Dec 12;12(12):e0189010. doi: 10.1371/journal.pone.0189010. eCollection 2017. |
Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy
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Citation:
Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y Epub:
Not Epub Abstract:
The pathogenesis of heart failure associated with dilated cardiomyopathy (DCM) may result in part from adenosine triphosphate (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri M, Takashima S, Kitakaze M, Hayashi K. Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy. Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y. |