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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions
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Citation:
JCI Insight. 2021 Jul 8;6(13):e130399. doi: 10.1172/jci.insight.130399 Epub:
Not Epub Abstract:
Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs, and LDLs and is essential for their production. Defects... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Templehof H, Moshe N, Avraham-Davidi I, Yaniv K. Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI Insight. 2021 Jul 8;6(13):e130399. doi: 10.1172/jci.insight.130399. |
Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis
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Citation:
Dev Biol. 2022 Dec 8:S0012-1606(22)00218-4. doi: 10.1016/j.ydbio.2022.11.007. Online ahead of print Epub:
Yes Abstract:
During neurovascular development, brain endothelial cells (BECs) respond to secreted signals from the neuroectoderm that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fetsko AR, Sebo DJ, Taylor MR. Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis. Dev Biol. 2022 Dec 8:S0012-1606(22)00218-4. doi: 10.1016/j.ydbio.2022.11.007. Online ahead of print. |
Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos
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Citation:
Int J Mol Sci. 2022; 23(24):15921. doi:10.3390/ijms232415921 Epub:
Not Epub Abstract:
After spinal cord injury (SCI) in mammals, neuronal regeneration is limited; in contrast, such regeneration occurs quickly in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee H-C, Lai W-L, Lin C-Y, Zeng C-W, Sheu J-C, Chou T-B, Tsai H-J.. Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos. Int J Mol Sci. 2022; 23(24):15921. doi:10.3390/ijms232415921. |
G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects
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Citation:
Nucleic Acids Res. 2022;gkac1108 doi:10.1093/nar/gkac1108 Epub:
Yes Abstract:
Friedreich’s ataxia is an incurable disease caused by frataxin (FXN) protein deficiency, which is mostly induced by GAA repeat... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: 293T Citation Extract: Wang F, Calvo-Roitberg E, Rembetsy-Brown JM, Fang M, Sousa J, Kartje ZJ, Krishnamurthy PM, Lee J, Green MR, Pai AA, Watts JK. G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects. Nucleic Acids Res. 2022;gkac1108 doi:10.1093/nar/gkac1108. |
gldc Is Essential for Renal Progenitor Patterning during Kidney Development
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Citation:
Biomedicines. 2022;10(12):3220. doi:10.3390/biomedicines10123220 Epub:
Not Epub Abstract:
The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane that is responsible for regulating glycine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weaver NE, Healy A, Wingert RA. gldc Is Essential for Renal Progenitor Patterning during Kidney Development. Biomedicines. 2022;10(12):3220. doi:10.3390/biomedicines10123220. |
GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development
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Citation:
Biomedicines. 2022;10(12):3208. doi:10.3390/biomedicines10123208 Epub:
Not Epub Abstract:
Genetic regulation of vascular patterning is not fully understood. Here, we report a novel gene, gtpbp1l (GTP-binding protein 1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lo Y-H, Huang Y-S, Chang Y-C, Hung P-Y, Wang W-D, Liu W, Urade R, Wen Z-H, Wu C-Y. GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development. Biomedicines. 2022;10(12):3208. doi:10.3390/biomedicines10123208. |
Disruption of fos causes craniofacial anomalies in developing zebrafish
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.12.06.519379 Epub:
Not Epub Abstract:
Craniofacial development is a complex and tightly regulated process and disruptions can lead to structural birth defects, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maili L, Tandon B, Yuan Q, Menezes S, Hashmi SS, Letra A, Eisenhoffer GT, Hecht JT. Disruption of fos causes craniofacial anomalies in developing zebrafish. bioRxiv. 2022;[preprint] doi:10.1101/2022.12.06.519379. |
Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development
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Citation:
EMBO J. 2022 Dec 7:e111364. doi: 10.15252/embj.2022111364. Online ahead of print Epub:
Yes Abstract:
Early embryonic development depends on proper utilization and clearance of maternal transcriptomes. How these processes are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xiao Y, Chen J, Yang S, Sun H, Xie L, Li J, Jing N, Zhu X. Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development. EMBO J. 2022 Dec 7:e111364. doi: 10.15252/embj.2022111364. Online ahead of print. |
Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis
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Citation:
Development. 2022 Dec 1;149(23):dev200754. doi: 10.1242/dev.200754. Epub 2022 Dec 5. PMID: 36468454 Epub:
Not Epub Abstract:
Developmentally, the great vessels of the heart originate from the pharyngeal arch arteries (PAAs). During PAA vasculogenesis,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu J, Zhang M, Dong H, Liu J, Mao A, Ning G, Cao Y, Zhang Y, Wang Q. Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis. Development. 2022 Dec 1;149(23):dev200754. doi: 10.1242/dev.200754. Epub 2022 Dec 5. PMID: 36468454. |
Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling
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Citation:
Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2201097119. doi: 10.1073/pnas.2201097119. Epub 2022 Dec 5 Epub:
Not Epub Abstract:
Despite the robust healing capacity of the liver, regenerative failure underlies numerous hepatic diseases, including the JAG1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS. Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2201097119. doi: 10.1073/pnas.2201097119. Epub 2022 Dec 5. |