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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Oxytocin neurons in the anterior and posterior paraventricular nucleus have distinct behavioral functions and electrophysiological profiles

Authors:
Chrisman AN, Sugimoto C, Butler-Struben H, Minie VA, Eagle AL, Anderson D, Duque-Wilckens N, Ramos A, Lewis YI, Archdeacon SC, Robison AJ, Trainor BC
Citation:
Neuropsychopharmacology. 2026 Jan 17. doi: 10.1038/s41386-026-02352-y. Epub ahead of print. PMID: 41548026
Epub:
Not Epub
Abstract:
Oxytocin is a neuropeptide that can promote or inhibit affiliative social behaviors. Recent evidence suggests that these...
Link:
https://www.nature.com/articles/s41386-026-02352-y
Delivery Method:
hypothalamus paraventricular nucleus injection
Organism or Cell Type:
California mice (Peromyscus californicus)
Citation Extract:
Chrisman AN, Sugimoto C, Butler-Struben H, Minie VA, Eagle AL, Anderson D, Duque-Wilckens N, Ramos A, Lewis YI, Archdeacon SC, Robison AJ, Trainor BC. Oxytocin neurons in the anterior and posterior paraventricular nucleus have distinct behavioral functions and electrophysiological profiles. Neuropsychopharmacology. 2026 Jan 17. doi: 10.1038/s41386-026-02352-y. Epub ahead of print. PMID: 41548026.

PATJ deficiency leads to cystic kidney disease and related ciliopathies

Authors:
Epting D, Braun DA, Decker E, Ott E, Eisenberger T, Bachmann N, Nedvetsky P, Krahn MP, Hildebrandt F, Bergmann C
Citation:
HGG Adv. 2026 Jan 15;7(1):100514. doi: 10.1016/j.xhgg.2025.100514. Epub 2025 Sep 9. PMID: 40931526; PMCID: PMC12512994
Epub:
Not Epub
Abstract:
Cystic kidney disease and related ciliopathies are caused by pathogenic variants in genes that commonly result in ciliary...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12512994/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Epting D, Braun DA, Decker E, Ott E, Eisenberger T, Bachmann N, Nedvetsky P, Krahn MP, Hildebrandt F, Bergmann C. PATJ deficiency leads to cystic kidney disease and related ciliopathies. HGG Adv. 2026 Jan 15;7(1):100514. doi: 10.1016/j.xhgg.2025.100514. Epub 2025 Sep 9. PMID: 40931526; PMCID: PMC12512994.

Rtf1-dependent transcriptional pausing regulates cardiogenesis

Authors:
Langenbacher AD, Lu F, Tsang L, Huang ZYS, Keer B, Tian Z, Eide A, Pellegrini M, Nakano H, Nakano A, Chen JN
Citation:
Elife. 2026 Jan 15;13:RP94524. doi: 10.7554/eLife.94524. PMID: 41537425; PMCID: PMC12807453
Epub:
Not Epub
Abstract:
Transcriptional pause-release critically regulates cellular RNA biogenesis, yet how dysregulation of this process impacts...
Link:
https://elifesciences.org/articles/94524
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langenbacher AD, Lu F, Tsang L, Huang ZYS, Keer B, Tian Z, Eide A, Pellegrini M, Nakano H, Nakano A, Chen JN. Rtf1-dependent transcriptional pausing regulates cardiogenesis. Elife. 2026 Jan 15;13:RP94524. doi: 10.7554/eLife.94524. PMID: 41537425; PMCID: PMC12807453.

The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision

Authors:
Chrystal PW, Lambacher NJ, Doucette LP, Bellingham J, Schiff ER, Noel NCL, Li C, Tsiropoulou S, Casey GA, Zhai Y, Nadolski NJ, Majumder MH, Tagoe J, D'Esposito F, Cordeiro MF, Downes S, Clayton-Smith J, Ellingford J; Genomics England Research Consortium; Mahroo OA, Hocking JC, Cheetham ME, Webster AR, Jansen G, Blacque OE, Allison WT, Au PYB, MacDonald IM, Arno G, Leroux MR
Citation:
Nat Commun. 2022 Nov 3;13(1):6595. doi: 10.1038/s41467-022-33820-w. PMID: 36329026; PMCID: PMC9633640
Epub:
Not Epub
Abstract:
Motile and non-motile cilia are associated with mutually-exclusive genetic disorders. Motile cilia propel sperm or...
Link:
https://www.nature.com/articles/s41467-022-33820-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrystal PW, Lambacher NJ, Doucette LP, Bellingham J, Schiff ER, Noel NCL, Li C, Tsiropoulou S, Casey GA, Zhai Y, Nadolski NJ, Majumder MH, Tagoe J, D'Esposito F, Cordeiro MF, Downes S, Clayton-Smith J, Ellingford J; Genomics England Research Consortium; Mahroo OA, Hocking JC, Cheetham ME, Webster AR, Jansen G, Blacque OE, Allison WT, Au PYB, MacDonald IM, Arno G, Leroux MR. The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision. Nat Commun. 2022 Nov 3;13(1):6595. doi: 10.1038/s41467-022-33820-w. PMID: 36329026; PMCID: PMC9633640.

Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking

Authors:
Zheng L, Duan X, Huang W, Luo Y, Wu Y, Lin Q, Wu X, Han L, Shen W
Citation:
Commun Biol. 2026 Jan 9. doi: 10.1038/s42003-025-09507-5. Epub ahead of print. PMID: 41507541
Epub:
Not Epub
Abstract:
Environmental light significantly influences neural development, yet the specific mechanisms underlying the effects of...
Link:
https://www.nature.com/articles/s42003-025-09507-5
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zheng L, Duan X, Huang W, Luo Y, Wu Y, Lin Q, Wu X, Han L, Shen W. Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking. Commun Biol. 2026 Jan 9. doi: 10.1038/s42003-025-09507-5. Epub ahead of print. PMID: 41507541.

Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo

Authors:
Mishra N, Li YI, Hannezo E, Heisenberg CP
Citation:
Nat. Phys. (2026). https://doi.org/10.1038/s41567-025-03122-1
Epub:
Not Epub
Abstract:
Early embryo geometry is one of the most invariant species-specific traits, yet its role in ensuring developmental...
Link:
https://www.nature.com/articles/s41567-025-03122-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mishra N, Li YI, Hannezo E, Heisenberg CP. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. Nat. Phys. (2026). https://doi.org/10.1038/s41567-025-03122-1.

Endothelial Cell-Specific Molecule-1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Authors:
Chen C, Ge X, Fu D, Mei H, Lv F, Yang C, Lu J, Shen X, Li B, Wang X, Liu D
Citation:
Adv Sci (Weinh). 2026 Jan 9:e15994. doi: 10.1002/advs.202515994. Epub ahead of print. PMID: 41517829
Epub:
Not Epub
Abstract:
Deficiencies in endogenous anticoagulation pathways can lead to vascular occlusion and thrombosis. Endothelial cell-specific...
Link:
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515994
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen C, Ge X, Fu D, Mei H, Lv F, Yang C, Lu J, Shen X, Li B, Wang X, Liu D. Endothelial Cell-Specific Molecule-1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis. Adv Sci (Weinh). 2026 Jan 9:e15994. doi: 10.1002/advs.202515994. Epub ahead of print. PMID: 41517829.

Cardiac and skeletal muscle delivery of biotherapeutics with a blood vessel epicardial substance-targeting peptide

Authors:
Wang B, Cao J, Wu J, Zhao Y, Zhang Y, Abendroth F, Lin C, Zhong L, Yu H, Seow Y, Ou M, Vázquez O, Mei L, Yin H, Han G
Citation:
Biomaterials. 2026 Jan 4;329:123986. doi: 10.1016/j.biomaterials.2026.123986. Epub ahead of print. PMID: 41506143
Epub:
Not Epub
Abstract:
Although peptide-based delivery strategies show promise for muscle and heart diseases, delivery of biotherapeutics to both...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0142961226000104
Delivery Method:
BV2 peptide-linked, exosome; injection
Organism or Cell Type:
mdx and dystrophin/utrophin double-knockout (DKO) mice
Citation Extract:
Wang B, Cao J, Wu J, Zhao Y, Zhang Y, Abendroth F, Lin C, Zhong L, Yu H, Seow Y, Ou M, Vázquez O, Mei L, Yin H, Han G. Cardiac and skeletal muscle delivery of biotherapeutics with a blood vessel epicardial substance-targeting peptide. Biomaterials. 2026 Jan 4;329:123986. doi: 10.1016/j.biomaterials.2026.123986. Epub ahead of print. PMID: 41506143.

dock11 Knockdown in Zebrafish Disrupts Embryogenesis: Insights Into the Genetic Causes of Early Pregnancy Loss

Authors:
Liu C, Wang M, Chen F, Chen M, Yao Y, Huang W
Citation:
J Cell Mol Med. 2026 Jan;30(1):e71017. doi: 10.1111/jcmm.71017. PMID: 41503681; PMCID: PMC12780853
Epub:
Not Epub
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12780853/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu C, Wang M, Chen F, Chen M, Yao Y, Huang W. dock11 Knockdown in Zebrafish Disrupts Embryogenesis: Insights Into the Genetic Causes of Early Pregnancy Loss. J Cell Mol Med. 2026 Jan;30(1):e71017. doi: 10.1111/jcmm.71017. PMID: 41503681; PMCID: PMC12780853.

Linear ubiquitination triggers Amph-mediated T-tubule biogenesis

Authors:
Kawaguchi K, Hama Y, Yoshikawa H, Nishino K, Morimoto K, Nakamura T, Koizumi M, Sakamaki Y, Abe K, Kakuta S, Ichimura K, Ikeda F, Kosako H, Fujita N
Citation:
Sci Adv. 2026 Jan 9;12(2):eady4934. doi: 10.1126/sciadv.ady4934. Epub 2026 Jan 7. PMID: 41499502; PMCID: PMC12778051
Epub:
Not Epub
Abstract:
Transverse tubules (T-tubules) are invaginations of the muscle plasma membrane that facilitate rapid transmission of action...
Link:
https://www.science.org/doi/10.1126/sciadv.ady4934
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kawaguchi K, Hama Y, Yoshikawa H, Nishino K, Morimoto K, Nakamura T, Koizumi M, Sakamaki Y, Abe K, Kakuta S, Ichimura K, Ikeda F, Kosako H, Fujita N. Linear ubiquitination triggers Amph-mediated T-tubule biogenesis. Sci Adv. 2026 Jan 9;12(2):eady4934. doi: 10.1126/sciadv.ady4934. Epub 2026 Jan 7. PMID: 41499502; PMCID: PMC12778051.

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