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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions

Authors:
Shih D-F, Hsiao C-D, Min M-Y, Lai W-S, Yang C-W, Lee W-T, Lee S-J
Citation:
PLoS ONE. 2013;8(8):e71741. doi:10.1371/journal.pone.0071741
Epub:
Not Epub
Abstract:
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare pediatric neuro-metabolic disease in children. Due to the lack...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shih D-F, Hsiao C-D, Min M-Y, Lai W-S, Yang C-W, Lee W-T, Lee S-J. Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions. PLoS ONE. 2013;8(8):e71741. doi:10.1371/journal.pone.0071741.

Bezafibrate stimulates canalicular localization of NBD-labeled phosphatidylcholine in HepG2 cells by PPARalpha -mediated redistribution of ABCB4

Authors:
Shoda J, Inada Y, Tsuji A, Kusama H, Ueda T, Ikegami T, Suzuki H, Sugiyama Y, Cohen DE, Tanaka N
Citation:
J Lipid Res. 2004 Oct;45(10):1813-1825. Epub 2004 Jul 16.
Epub:
Not Epub
Abstract:
By micellization, biliary phospholipids protect against bile duct injury by hydrophobic bile acids. Decreased function of ATP...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: human hepatocyte HepG2
Citation Extract:
Shoda J, Inada Y, Tsuji A, Kusama H, Ueda T, Ikegami T, Suzuki H, Sugiyama Y, Cohen DE, Tanaka N. Bezafibrate stimulates canalicular localization of NBD-labeled phosphatidylcholine in HepG2 cells by PPARalpha -mediated redistribution of ABCB4. J Lipid Res. 2004 Oct;45(10):1813-1825. Epub 2004 Jul 16..

Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue

Authors:
Shimizu T, Bae YK, Hibi M
Citation:
Development. 2006 Dec;133(23):4709-19. Epub 2006 Nov 1
Epub:
Not Epub
Abstract:
Fibroblast growth factor (Fgf) and retinoic acid (RA) signals control the formation and anteroposterior patterning of posterior...
Organism or Cell Type:
zebrafish
Citation Extract:
Shimizu T, Bae YK, Hibi M. Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue. Development. 2006 Dec;133(23):4709-19. Epub 2006 Nov 1.

Characterization of the RNA-binding protein Musashi1 in zebrafish

Authors:
Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H
Citation:
Brain Res. 2012 Feb 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Musashi (Msi) is an evolutionarily conserved gene family of RNA-binding proteins (RBPs) that is preferentially expressed in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Characterization of the RNA-binding protein Musashi1 in zebrafish. Brain Res. 2012 Feb 3. [Epub ahead of print].

Chemical technologies for probing embryonic development

Authors:
Shestopalov IA, Chen JK
Citation:
Chem Soc Rev. 2008 Jul;37(7):1294-307. Epub 2008 May 7. Review
Epub:
Not Epub
Abstract:
Embryogenesis is a remarkable program of cell proliferation, migration, and differentiation that transforms a single fertilized...
Citation Extract:
Shestopalov IA, Chen JK. Chemical technologies for probing embryonic development. Chem Soc Rev. 2008 Jul;37(7):1294-307. Epub 2008 May 7. Review.

Chemokine signaling guides regional patterning of the first embryonic artery

Authors:
Siekmann AF, Standley C, Fogarty KE, Wolfe SA, Lawson ND
Citation:
Genes Dev. 2009 Oct 1;23(19):2272-7
Epub:
Not Epub
Abstract:
The aorta traverses the body, yet little is known about how it is patterned in different anatomical locations. Here, we show...
Organism or Cell Type:
zebrafish
Citation Extract:
Siekmann AF, Standley C, Fogarty KE, Wolfe SA, Lawson ND. Chemokine signaling guides regional patterning of the first embryonic artery. Genes Dev. 2009 Oct 1;23(19):2272-7.

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3

Authors:
Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D'Andrea AA, Look AT
Citation:
Cell. 2008 May 30;133(5):864-77
Epub:
Not Epub
Abstract:
Evasion of DNA damage-induced cell death, via mutation of the p53 tumor suppressor or overexpression of prosurvival Bcl-2...
Organism or Cell Type:
zebrafish
Citation Extract:
Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D'Andrea AA, Look AT. Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell. 2008 May 30;133(5):864-77.

Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation

Authors:
Sheng G, dos Reis M, Stern CD
Citation:
Cell. 2003 Nov 26;115(5):603-13
Epub:
Not Epub
Abstract:
Gastrulation generates mesoderm and endoderm from embryonic epiblast; soon after, the neural plate is established within the...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Sheng G, dos Reis M, Stern CD. Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation. Cell. 2003 Nov 26;115(5):603-13.

Ci-Pem-1 localizes to the nucleus and represses somatic gene transcription in the germline of Ciona intestinalis embryos

Authors:
Shirae-Kurabayashi M, Matsuda K, Nakamura A
Citation:
Development. 2011 Jul;138(14):2871-81
Epub:
Not Epub
Abstract:
In many animal embryos, germ-cell formation depends on maternal factors located in the germ plasm. To ensure the development of...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Shirae-Kurabayashi M, Matsuda K, Nakamura A. Ci-Pem-1 localizes to the nucleus and represses somatic gene transcription in the germline of Ciona intestinalis embryos. Development. 2011 Jul;138(14):2871-81.

Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect

Authors:
Sheng D, Qu D, Kwok KH, Ng SS, Lim AY, Aw SS, Lee CW, Sung WK, Tan EK, Lufkin T, Jesuthasan S, Sinnakaruppan M, Liu J
Citation:
PLoS Genet. 2010 Apr 22;6(4):e1000914
Epub:
Not Epub
Abstract:
LRRK2 plays an important role in Parkinson's disease (PD), but its biological functions are largely unknown. Here, we...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sheng D, Qu D, Kwok KH, Ng SS, Lim AY, Aw SS, Lee CW, Sung WK, Tan EK, Lufkin T, Jesuthasan S, Sinnakaruppan M, Liu J. Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect. PLoS Genet. 2010 Apr 22;6(4):e1000914.

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