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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Maternal-zygotic medaka mutants for fgfr1 reveal its essential role in the migration of the axial mesoderm but not the lateral mesoderm

Authors:
Shimada A, Yabusaki M, Niwa H, Yokoi H, Hatta K, Kobayashi D, Takeda H
Citation:
Development. 2008 Jan;135(2):281-90
Epub:
Not Epub
Abstract:
The medaka fish (Oryzias latipes) is an emerging model organism for which a variety of unique developmental mutants have now...
Organism or Cell Type:
medaka
Citation Extract:
Shimada A, Yabusaki M, Niwa H, Yokoi H, Hatta K, Kobayashi D, Takeda H. Maternal-zygotic medaka mutants for fgfr1 reveal its essential role in the migration of the axial mesoderm but not the lateral mesoderm. Development. 2008 Jan;135(2):281-90.

Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development

Authors:
Simms RJ, Hynes AM, Eley L, Inglis D, Chaudhry B, Dawe HR, Sayer JA
Citation:
Cell Mol Life Sci. 2011 Sep 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Joubert syndrome and related diseases (JSRD) are cerebello-oculo-renal syndromes with phenotypes including cerebellar...
Organism or Cell Type:
zebrafish
Citation Extract:
Simms RJ, Hynes AM, Eley L, Inglis D, Chaudhry B, Dawe HR, Sayer JA. Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development. Cell Mol Life Sci. 2011 Sep 29. [Epub ahead of print].

Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells

Authors:
Shieh JJ, Liu KT, Huang SW, Chen YJ, Hsieh TY
Citation:
J Invest Dermatol. 2009 Oct;129(10):2497-506. doi: 10.1038/jid.2009.83. Epub 2009 Apr 16.
Epub:
Not Epub
Abstract:
Myeloid cell leukemia-1 (Mcl-1, Mcl-1L) is an anti-apoptotic protein of the Bcl-2 family that acts as a critical molecule in...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human basal skin cell carcinoma line
Citation Extract:
Shieh JJ, Liu KT, Huang SW, Chen YJ, Hsieh TY. Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells. J Invest Dermatol. 2009 Oct;129(10):2497-506. doi: 10.1038/jid.2009.83. Epub 2009 Apr 16..

Multiple roles for Med12 in vertebrate endoderm development

Authors:
Shin CH, Chung WS, Hong SK, Ober EA, Verkade H, Field HA, Huisken J, Stainier DY
Citation:
Dev Biol. 2008 May 15;317(2):467-79. Epub 2008 Mar 4
Epub:
Not Epub
Abstract:
In zebrafish, the endoderm originates at the blastula stage from the most marginal blastomeres. Through a series of complex...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shin CH, Chung WS, Hong SK, Ober EA, Verkade H, Field HA, Huisken J, Stainier DY. Multiple roles for Med12 in vertebrate endoderm development. Dev Biol. 2008 May 15;317(2):467-79. Epub 2008 Mar 4.

Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension

Authors:
Shwartz Y, Farkas Z, Stern T, Aszódi A, Zelzer E
Citation:
Dev Biol. 2012;[Epub ahead of print] doi: 10.1016/j.ydbio.2012.07.026
Epub:
Not Epub
Abstract:
Convergent extension driven by mediolateral intercalation of chondrocytes is a key process that contributes to skeletal growth...
Organism or Cell Type:
zebrafish
Citation Extract:
Shwartz Y, Farkas Z, Stern T, Aszódi A, Zelzer E. Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension. Dev Biol. 2012;[Epub ahead of print] doi: 10.1016/j.ydbio.2012.07.026.

N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons

Authors:
Shiau CE, Bronner-Fraser M
Citation:
Development. 2009 Dec;136(24):4155-64
Epub:
Not Epub
Abstract:
Vertebrate cranial sensory ganglia have a dual origin from the neural crest and ectodermal placodes. In the largest of these,...
Organism or Cell Type:
chick embryo
Citation Extract:
Shiau CE, Bronner-Fraser M. N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons. Development. 2009 Dec;136(24):4155-64.

Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning

Authors:
Shu X, Huang J, Dong Y, Choi J, Langenbacher A, Chen JN
Citation:
Development. 2007 May;134(10):1921-30. Epub 2007 Apr 18
Epub:
Not Epub
Abstract:
A conserved molecular cascade involving Nodal signaling that patterns the laterality of the lateral mesoderm in vertebrates has...
Organism or Cell Type:
zebrafish
Citation Extract:
Shu X, Huang J, Dong Y, Choi J, Langenbacher A, Chen JN. Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning. Development. 2007 May;134(10):1921-30. Epub 2007 Apr 18.

Na,K-ATPase is essential for embryonic heart development in the zebrafish

Authors:
Shu X, Cheng K, Patel N, Chen F, Joseph E, Tsai HJ, Chen JN.
Citation:
Development. 2003 Dec; 130(25): 6165-73. Epub 2003 Nov 05
Epub:
Not Epub
Abstract:
Na,K-ATPase is an essential gene maintaining electrochemical gradients across the plasma membrane. Although previous studies...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shu X, Cheng K, Patel N, Chen F, Joseph E, Tsai HJ, Chen JN.. Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development. 2003 Dec; 130(25): 6165-73. Epub 2003 Nov 05.

NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction

Authors:
Sidi S, Friedrich RW, Nicolson T
Citation:
Science. 2003 Jul 4;301(5629):96-9. Epub 2003 Jun 12.
Epub:
Not Epub
Abstract:
The senses of hearing and balance in vertebrates rely upon the sensory hair cells (HCs) of the inner ear. The central element...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sidi S, Friedrich RW, Nicolson T. NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction. Science. 2003 Jul 4;301(5629):96-9. Epub 2003 Jun 12..

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

Authors:
Siekmann AF, Lawson ND
Citation:
Nature. 2007 Feb 15;445(7129):781-4. Epub 2007 Jan 28.
Epub:
Not Epub
Abstract:
Recent evidence indicates that growing blood-vessel sprouts consist of endothelial cells with distinct cell fates and...
Organism or Cell Type:
zebrafish
Citation Extract:
Siekmann AF, Lawson ND. Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature. 2007 Feb 15;445(7129):781-4. Epub 2007 Jan 28..

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