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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling

Authors:
Priyadarshini M, Tuimala J, Chen YC, Panula P
Citation:
Neurobiol Dis. 2013 Feb 27. doi:pii: S0969-9961(13)00064-8. 10.1016/j.nbd.2013.02.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The PTEN induced putative kinase 1 (PINK1) gene is mutated in patients with hereditary early onset Parkinson's disease (PD...
Organism or Cell Type:
zebrafish
Citation Extract:
Priyadarshini M, Tuimala J, Chen YC, Panula P. A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling. Neurobiol Dis. 2013 Feb 27. doi:pii: S0969-9961(13)00064-8. 10.1016/j.nbd.2013.02.002. [Epub ahead of print].

Adaptive autoimmunity and foxp3-based immunoregulation in zebrafish

Authors:
Quintana FJ, Iglesias AH, Farez MF, Caccamo M, Burns EJ, Kassam N, Oukka M, Weiner HL
Citation:
PLoS One. 2010 Mar 5;5(3):e9478
Epub:
Not Epub
Abstract:
BACKGROUND: Jawed vertebrates generate their immune-receptor repertoire by a recombinatorial mechanism that has the potential...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quintana FJ, Iglesias AH, Farez MF, Caccamo M, Burns EJ, Kassam N, Oukka M, Weiner HL. Adaptive autoimmunity and foxp3-based immunoregulation in zebrafish. PLoS One. 2010 Mar 5;5(3):e9478.

Amyloid Precursor Proteins Interact with the Heterotrimeric G Protein Go in the Control of Neuronal Migration

Authors:
Ramaker JM, Swanson TL, Copenhaver PF
Citation:
J Neurosci. 2013;33(24):10165-10181. doi:10.1523/​JNEUROSCI.1146-13.2013
Epub:
Not Epub
Abstract:
Amyloid precursor protein (APP) belongs to a family of evolutionarily conserved transmembrane glycoproteins that has been...
Organism or Cell Type:
cell culture: GV1
Citation Extract:
Ramaker JM, Swanson TL, Copenhaver PF. Amyloid Precursor Proteins Interact with the Heterotrimeric G Protein Go in the Control of Neuronal Migration. J Neurosci. 2013;33(24):10165-10181. doi:10.1523/​JNEUROSCI.1146-13.2013.

An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry

Authors:
Regan JC, Concha ML, Roussigne M, Russell C, Wilson SW
Citation:
Neuron. 2009 Jan 15;61(1):27-34
Epub:
Not Epub
Abstract:
Neuroanatomical and functional asymmetries are universal features of the vertebrate CNS, but how asymmetry is generated is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Regan JC, Concha ML, Roussigne M, Russell C, Wilson SW. An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry. Neuron. 2009 Jan 15;61(1):27-34.

Antisense therapeutics for neurofibromatosis type 1 caused by deep intronic mutations

Authors:
Pros E, Fernández-Rodríguez J, Canet B, Benito L, Sánchez A, Benavides A, Ramos FJ, López-Ariztegui MA, Capellá G, Blanco I, Serra E, Lázaro C
Citation:
Hum Mutat. 2009 Feb 24;30(3):454-462. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder affecting 1:3,500 individuals. Disease expression is highly...
Organism or Cell Type:
cell culture: primary fibroblast and lymphocytes
Citation Extract:
Pros E, Fernández-Rodríguez J, Canet B, Benito L, Sánchez A, Benavides A, Ramos FJ, López-Ariztegui MA, Capellá G, Blanco I, Serra E, Lázaro C. Antisense therapeutics for neurofibromatosis type 1 caused by deep intronic mutations. Hum Mutat. 2009 Feb 24;30(3):454-462. [Epub ahead of print].

ARNT2 Is Not Required for TCDD Developmental Toxicity in Zebrafish

Authors:
Prasch AL, Heideman W, Peterson RE
Citation:
Toxicol Sci. 2004 Nov;82(1):250-8. Epub 2004 Jul 28
Epub:
Not Epub
Abstract:
ZfAHR2 has been identified as the receptor that is essential for mediating the developmental toxicity caused by 2,3,7,8-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prasch AL, Heideman W, Peterson RE. ARNT2 Is Not Required for TCDD Developmental Toxicity in Zebrafish. Toxicol Sci. 2004 Nov;82(1):250-8. Epub 2004 Jul 28.

Aryl Hydrocarbon Receptor 2 Mediates 2,3,7,8-Tetrachlorodibenzo-p-dioxin Developmental Toxicity in Zebrafish

Authors:
Prasch AL, Teraoka H, Carney SA, Dong W, Hiraga T, Stegeman JJ, Heideman W, Peterson RE
Citation:
Toxicol Sci. 2003 Nov;76(1):138-50. Epub 2003 Jul 25.
Epub:
Not Epub
Abstract:
In order to use the zebrafish as a model vertebrate to investigate the developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prasch AL, Teraoka H, Carney SA, Dong W, Hiraga T, Stegeman JJ, Heideman W, Peterson RE. Aryl Hydrocarbon Receptor 2 Mediates 2,3,7,8-Tetrachlorodibenzo-p-dioxin Developmental Toxicity in Zebrafish. Toxicol Sci. 2003 Nov;76(1):138-50. Epub 2003 Jul 25..

Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway

Authors:
Ramachandran R, Fausett BV, Goldman D
Citation:
Nat Cell Biol. 2010 Oct 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Unlike mammals, teleost fish mount a robust regenerative response to retinal injury that culminates in restoration of visual...
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran R, Fausett BV, Goldman D. Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nat Cell Biol. 2010 Oct 10. [Epub ahead of print].

Ascl1a/Dkk/{beta}-catenin signaling pathway is necessary and glycogen synthase kinase-3{beta} inhibition is sufficient for zebrafish retina regeneration

Authors:
Ramachandran R, Zhao XF, Goldman D
Citation:
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15858-63. Epub 2011 Sep 12.
Epub:
Not Epub
Abstract:
Key to successful retina regeneration in zebrafish are Müller glia (MG) that respond to retinal injury by dedifferentiating...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran R, Zhao XF, Goldman D. Ascl1a/Dkk/{beta}-catenin signaling pathway is necessary and glycogen synthase kinase-3{beta} inhibition is sufficient for zebrafish retina regeneration. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15858-63. Epub 2011 Sep 12..

Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration

Authors:
Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD
Citation:
Mol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2
Epub:
Not Epub
Abstract:
Important roles for vascular endothelial growth factor (VEGF) and autotaxin (ATX) have been established for embryonic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs)
Citation Extract:
Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD. Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration. Mol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2.

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