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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Impaired neural development in a zebrafish model for Lowe syndrome
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Citation:
Hum Mol Genet. 2012 Apr 15;21(8):1744-59. Epub 2011 Dec 30. Epub:
Not Epub Abstract:
Lowe syndrome, which is characterized by defects in the central nervous system, eyes and kidneys, is caused by mutation of the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramirez IB, Pietka G, Jones DR, Divecha N, Alia A, Baraban SC, Hurlstone AF, Lowe M. Impaired neural development in a zebrafish model for Lowe syndrome. Hum Mol Genet. 2012 Apr 15;21(8):1744-59. Epub 2011 Dec 30.. |
In the Absence of Sonic Hedgehog, p53 Induces Apoptosis and Inhibits Retinal Cell Proliferation, Cell-Cycle Exit and Differentiation in Zebrafish
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Citation:
PLoS ONE. 2010;5(10): e13549. doi:10.1371/journal.pone.0013549 Epub:
Not Epub Abstract:
Background Sonic hedgehog (Shh) signaling regulates cell proliferation during vertebrate development via induction of cell-... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Prykhozhij SV. In the Absence of Sonic Hedgehog, p53 Induces Apoptosis and Inhibits Retinal Cell Proliferation, Cell-Cycle Exit and Differentiation in Zebrafish. PLoS ONE. 2010;5(10): e13549. doi:10.1371/journal.pone.0013549. |
Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina
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Citation:
Nat Cell Biol. 2012 Oct;14(10):1013-23. doi: 10.1038/ncb2586. Epub 2012 Sep 23 Epub:
Not Epub Abstract:
In zebrafish, retinal injury stimulates Müller glia (MG) reprograming, allowing them to generate multipotent progenitors that... Delivery Method:
in vivo: injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Ramachandran R, Zhao XF, Goldman D. Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina. Nat Cell Biol. 2012 Oct;14(10):1013-23. doi: 10.1038/ncb2586. Epub 2012 Sep 23. |
Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos
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Citation:
PLoS Biol. 2013 11(1):e1001467. doi:10.1371/journal.pbio.1001467 Epub:
Not Epub Abstract:
The initial regulatory state of most cells in many deuterostome embryos, including those of vertebrates and sea urchins,... Delivery Method:
Microinjection Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus Citation Extract: Range RC, Angerer RC, Angerer LM. Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos. PLoS Biol. 2013 11(1):e1001467. doi:10.1371/journal.pbio.1001467. |
KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes
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Citation:
Nat Genet. 2011 Jun;43(6):601-6. Epub 2011 May 8 Epub:
Not Epub Abstract:
KIF7, the human ortholog of Drosophila Costal2, is a key component of the Hedgehog signaling pathway. Here we report mutations... Organism or Cell Type:
zebrafish Citation Extract: Putoux A, Thomas S, Coene KL, Davis EE, Alanay Y, Ogur G, Uz E, Buzas D, Gomes C, Patrier S, Bennett CL, Elkhartoufi N, Frison MH, Rigonnot L, Joyé N, Pruvost S, Utine GE, Boduroglu K, Nitschke P, Fertitta L, Thauvin-Robinet C, Munnich A, Cormier-Daire V, Hennekam R, Colin E, Akarsu NA, Bole-Feysot C, Cagnard N, Schmitt A, Goudin N, Lyonnet S, Encha-Razavi F, Siffroi JP, Winey M, Katsanis N, Gonzales M, Vekemans M, Beales PL, Attié-Bitach T. KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes. Nat Genet. 2011 Jun;43(6):601-6. Epub 2011 May 8. |
Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3
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Citation:
Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):775-780. Epub 2009 Dec 22 Epub:
Not Epub Abstract:
Genome-wide association studies identified noncoding SNPs associated with type 2 diabetes and obesity in linkage disequilibrium... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes O, Engström PG, Alonso ME, Mustienes ED, Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, Argenton F, Lenhard B, Becker TS. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):775-780. Epub 2009 Dec 22. |
Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53
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Citation:
N Biotechnol. 2010 Nov 4. [Epub ahead of print] Epub:
Not Epub Abstract:
EMSY interacts directly with BRCA2 and links the BRCA2 pathway to sporadic breast and ovarian cancer. It also interacts with... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Rana AA, Roper SJ, Palmer EA, Smith JC. Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53. N Biotechnol. 2010 Nov 4. [Epub ahead of print]. |
LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo
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Citation:
Development. 2008 Jul;135(14):2445-54. Epub 2008 Jun 11. Epub:
Not Epub Abstract:
Activation of the Notch signaling pathway segregates the non-skeletogenic mesoderm (NSM) from the endomesoderm during sea... Delivery Method:
Microinjection Organism or Cell Type:
sea urchin Citation Extract: Range RC, Glenn TD, Miranda E, McClay DR. LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo. Development. 2008 Jul;135(14):2445-54. Epub 2008 Jun 11.. |
Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo
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Citation:
Dev Biol. 2011 Jul 12. [Epub ahead of print] Epub:
Not Epub Abstract:
The TGFβ family member Nodal is expressed early in the presumptive ventral ectoderm of the early sea urchin embryo and its... Organism or Cell Type:
P. lividus Citation Extract: Range R, Lepage T. Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo. Dev Biol. 2011 Jul 12. [Epub ahead of print]. |
Microarray Analysis of Prothrombin Knockdown in Zebrafish
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Citation:
Journal of Thrombosis and Haemostasis 2007; Volume 5, Supplement 1 :P1212 Epub:
Not Epub Abstract:
Prothrombin is the zymogen of thrombin that plays a pivotal role in coagulation. Knockdown of prothrombin in the zebrafish was... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pudur J. Microarray Analysis of Prothrombin Knockdown in Zebrafish. Journal of Thrombosis and Haemostasis 2007; Volume 5, Supplement 1 :P1212. |