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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish

Authors:
Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT
Citation:
Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20
Epub:
Not Epub
Abstract:
The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT. Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20.

Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN

Authors:
Ramachandran S, Ruef B, Pich C, Sprague J
Citation:
Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18
Epub:
Not Epub
Abstract:
The zebrafish model organism database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran S, Ruef B, Pich C, Sprague J. Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN. Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18.

Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration

Authors:
Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC
Citation:
Hum Mol Genet. 2011 Jan 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Bardet-Biedl Syndrome (BBS) is a syndromic form of retinal degeneration. Recently, homozygosity mapping with a consanguineous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC. Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration. Hum Mol Genet. 2011 Jan 31. [Epub ahead of print].

Germline gain-of-function mutations in RAF1 cause Noonan syndrome

Authors:
Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R
Citation:
Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1.
Epub:
Not Epub
Abstract:
Noonan syndrome is characterized by short stature, facial dysmorphia and a wide spectrum of congenital heart defects. Mutations...
Organism or Cell Type:
zebrafish
Citation Extract:
Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R. Germline gain-of-function mutations in RAF1 cause Noonan syndrome. Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1..

Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas

Authors:
Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK
Citation:
Diabetes. 2002 Nov;51(11):3229-36
Epub:
Not Epub
Abstract:
The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to endocrine and exocrine cells....
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse embryonic tissue
Citation Extract:
Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK. Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas. Diabetes. 2002 Nov;51(11):3229-36.

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins

Authors:
Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I
Citation:
Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16
Epub:
Not Epub
Abstract:
Haems are metalloporphyrins that serve as prosthetic groups for various biological processes including respiration, gas sensing...
Organism or Cell Type:
zebrafish
Citation Extract:
Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16.

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

Authors:
Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y
Citation:
Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11
Epub:
Not Epub
Abstract:
X-linked mental retardation (XLMR) is a complex human disease that causes intellectual disability. Causal mutations have been...
Organism or Cell Type:
zebrafish
Citation Extract:
Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11.

Hitting Bacteria at the Heart of the Central Dogma: Sequence-Specific Inhibition

Authors:
Rasmussen LC, Sperling-Petersen HU, Mortensen KK
Citation:
Microb Cell Fact. 2007 Aug 10;6(1):24 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: An important objective in developing new drugs is the achievement of high specificity to maximize curing effect and...
Organism or Cell Type:
Bacteria (review)
Citation Extract:
Rasmussen LC, Sperling-Petersen HU, Mortensen KK. Hitting Bacteria at the Heart of the Central Dogma: Sequence-Specific Inhibition. Microb Cell Fact. 2007 Aug 10;6(1):24 [Epub ahead of print] .

Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long Isoform

Authors:
Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield VC, Slusarski DC
Citation:
PLoS Genet. 2010 Mar 19;6(3):e1000884
Epub:
Not Epub
Abstract:
Bardet-Biedl Syndrome (BBS) is a heterogeneous syndromic form of retinal degeneration. We have identified a novel transcript of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield VC, Slusarski DC. Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long Isoform. PLoS Genet. 2010 Mar 19;6(3):e1000884.

Identification of zebrafish ARNT1 homologs: TCDD toxicity in the developing zebrafish requires ARNT1

Authors:
Prasch AL, Tanguay RL, Mehta V, Heideman W, Peterson RE
Citation:
2006 Mar;69(3):776-87. Epub 2005 Nov 23.
Epub:
Not Epub
Abstract:
In order to use the zebrafish as a model to study 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) developmental toxicity, it is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prasch AL, Tanguay RL, Mehta V, Heideman W, Peterson RE. Identification of zebrafish ARNT1 homologs: TCDD toxicity in the developing zebrafish requires ARNT1. 2006 Mar;69(3):776-87. Epub 2005 Nov 23..

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