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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10468 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

A Mutation in a Ganglioside Biosynthetic Enzyme, ST3GAL5, Results in Salt & Pepper Syndrome, a Neurocutaneous Disorder with Altered Glycolipid and Glycoprotein Glycosylation

Authors:
Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE
Citation:
Hum Mol Genet. 2013 Sep 10. [Epub ahead of print]
Abstract:
\"Salt & Pepper\" syndrome is an autosomal recessive condition characterized by severe intellectual disability,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE. A Mutation in a Ganglioside Biosynthetic Enzyme, ST3GAL5, Results in Salt & Pepper Syndrome, a Neurocutaneous Disorder with Altered Glycolipid and Glycoprotein Glycosylation. Hum Mol Genet. 2013 Sep 10. [Epub ahead of print].

A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification

Authors:
Bonano M, Tríbulo C, De Calisto J, Marchant L, Sánchez SS, Mayor R, Aybar MJ
Citation:
Dev Biol. 2008 Aug 15. [Epub ahead of print]
Abstract:
The neural crest is induced at the border of the neural plate in a multistep process by signals emanated from the epidermis,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bonano M, Tríbulo C, De Calisto J, Marchant L, Sánchez SS, Mayor R, Aybar MJ. A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification. Dev Biol. 2008 Aug 15. [Epub ahead of print] .

A primer for morpholino use in zebrafish

Authors:
Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC
Citation:
Zebrafish. 2009 Mar;6(1):69-77
Abstract:
Abstract Morpholino oligonucleotides are the most common anti-sense \"knockdown\" technique used in zebrafish (Danio...
Organism or Cell Type:
zebrafish
Citation Extract:
Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC. A primer for morpholino use in zebrafish. Zebrafish. 2009 Mar;6(1):69-77.

A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs

Authors:
Betancur P, Sauka-Spengler T, Bronner M
Citation:
Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20
Abstract:
The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Betancur P, Sauka-Spengler T, Bronner M. A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20.

A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development

Authors:
Bohnsack BL, Kasprick DS, Kish PE, Goldman D, Kahana A
Citation:
Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print]
Abstract:
Purpose.The homeobox transcription factor PITX2 is a known regulator of mammalian ocular development, and human PITX2 mutations...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bohnsack BL, Kasprick DS, Kish PE, Goldman D, Kahana A. A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development. Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print].

Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation

Authors:
Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Locker M, Perron M
Citation:
Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16
Abstract:
Continuous neurogenesis in the adult nervous system requires a delicate balance between proliferation and differentiation....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Locker M, Perron M. Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation. Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16.

Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis

Authors:
Boglev Y, Badrock AP, Trotter AJ, Du Q, Richardson EJ, Parslow AC, Markmiller SJ, Hall NE, de Jong-Curtain TA, Ng AY, Verkade H, Ober EA, Field HA, Shin D, Shin CH, Hannan KM, Hannan RD, Pearson RB, Kim S-H, Ess KC, Lieschke GJ, Stainier DYR, Heath JK
Citation:
PLoS Genet. 2013;9(2):e1003279. doi:10.1371/journal.pgen.1003279
Abstract:
Ribosome biogenesis underpins cell growth and division. Disruptions in ribosome biogenesis and translation initiation are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boglev Y, Badrock AP, Trotter AJ, Du Q, Richardson EJ, Parslow AC, Markmiller SJ, Hall NE, de Jong-Curtain TA, Ng AY, Verkade H, Ober EA, Field HA, Shin D, Shin CH, Hannan KM, Hannan RD, Pearson RB, Kim S-H, Ess KC, Lieschke GJ, Stainier DYR, Heath JK. Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis. PLoS Genet. 2013;9(2):e1003279. doi:10.1371/journal.pgen.1003279.

beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2

Authors:
Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS
Citation:
Dev Cell. 2010 Aug 17;19(2):220-31
Abstract:
An emerging concept in development is that transcriptional poising presets patterns of gene expression in a manner that...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS. beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220-31.

BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis

Authors:
Bielen H, Houart C
Citation:
Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006
Abstract:
Depletion of Wnt signaling is a major requirement for the induction of the anterior prosencephalon. However, the molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bielen H, Houart C. BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis. Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006.

C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

Authors:
Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, Macrae CA, Rosenzweig A, Spiegelman BM
Citation:
Cell. 2010 Dec 23;143(7):1072-83
Abstract:
The heart has the ability to grow in size in response to exercise, but little is known about the transcriptional mechanisms...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, Macrae CA, Rosenzweig A, Spiegelman BM. C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling. Cell. 2010 Dec 23;143(7):1072-83.

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