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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12091 scientific papers returned from the database with the search filters currently being used below.
There are 12091 scientific papers returned from the database with the search filters currently being used below.
Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers
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Citation:
Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1. Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMO), which have a neutral chemistry, are extensively being used as tools for... Organism or Cell Type:
cell culture Citation Extract: Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers. Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1.. |
Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake
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Citation:
Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059 Epub:
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Freshwater (FW) fishes actively absorb salt from their environment to tolerate low salinities. We previously reported that... Organism or Cell Type:
zebrafish Citation Extract: Ito Y, Kobayashi S, Nakamura N, Esaki M, Miyagi H, Hoshijima K, Hirose S. Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake. Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059. |
Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation
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Citation:
Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16. Epub:
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Hypopigmentation is a feature of copper deficiency in humans, as caused by mutation of the copper (Cu(2+)) transporter ATP7A in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE. Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16.. |
Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses
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Citation:
J Biol Chem. 2009 Jan 9;284(2):1116-25. Epub 2008 Nov 11 Epub:
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Thrombospondin-1 regulates nitric oxide (NO) signaling in vascular cells via CD47. Because CD47 binding motifs are conserved in... Organism or Cell Type:
cell culture: primary TSP1-null vascular cells Citation Extract: Isenberg JS, Annis DS, Pendrak ML, Ptaszynska M, Frazier WA, Mosher DF, Roberts DD. Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses. J Biol Chem. 2009 Jan 9;284(2):1116-25. Epub 2008 Nov 11. |
Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections
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Citation:
Viruses. 2012;4(11):2806-2830. doi:10.3390/v4112806 Epub:
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There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to... Organism or Cell Type:
Ebola and Marburg virus, various hosts Citation Extract: Iversen PL, Warren TK, Wells JB, Garza NL, Mourich DV, Welch LS, Panchal RG, Bavari S. Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections. Viruses. 2012;4(11):2806-2830. doi:10.3390/v4112806. |
Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells
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Citation:
Pathol Int. 2004 Feb; 54(2): 77-81 Epub:
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Lumican is a member of the small-leucine-rich proteoglycan (SLRP) family and is overexpressed during wound healing of the... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: human embryonic kidney (HEK 293) Citation Extract: Ishiwata T, Fujii T, Ishiwata S, Ikegawa S, Naito Z. Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells. Pathol Int. 2004 Feb; 54(2): 77-81. |
Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans
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Citation:
Clin Cancer Res. 2003 Jul;9(7):2510-9 Epub:
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PURPOSE: The overexpression of c-myc associated with uncontrolled cell proliferation is a frequent genetic event in androgen-... Delivery Method:
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Cell Culture: PC-3 human androgen-independent prostate carcinoma Citation Extract: Iversen PL, Arora V, Acker AJ, Mason DH, Devi GR. Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans. Clin Cancer Res. 2003 Jul;9(7):2510-9. |
Emergence of traveling waves in the zebrafish segmentation clock
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Citation:
Development. 2010 May;137(10):1595-9. doi: 10.1242/dev.046888. Epub 2010 Apr 14. Epub:
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The spatial and temporal periodicity of somite formation is controlled by the segmentation clock, in which numerous cells... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ishimatsu K, Takamatsu A, Takeda H. Emergence of traveling waves in the zebrafish segmentation clock. Development. 2010 May;137(10):1595-9. doi: 10.1242/dev.046888. Epub 2010 Apr 14.. |
Evaluation of Antisense Mechanisms of Action
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Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies. Phillips I, Abelson J, Simon M eds. Methods in Enzymology. 1999 313: Epub:
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Citation Extract: Iversen P, Ghosh C, Stein D, Weller D. Evaluation of Antisense Mechanisms of Action. Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies. Phillips I, Abelson J, Simon M eds. Methods in Enzymology. 1999 313:. |
Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos
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Citation:
Mech Dev. 2008 Jan-Feb;125(1-2):58-66. Epub 2007 Oct 12 Epub:
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The blastula Chordin- and Noggin-expressing (BCNE) center located in the dorsal animal region of the Xenopus blastula embryo... Organism or Cell Type:
Xenopus laevis Citation Extract: Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, Robertis EM, Kuroda H. Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mech Dev. 2008 Jan-Feb;125(1-2):58-66. Epub 2007 Oct 12. |