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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos

Authors:
Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, Robertis EM, Kuroda H
Citation:
Mech Dev. 2008 Jan-Feb;125(1-2):58-66. Epub 2007 Oct 12
Epub:
Not Epub
Abstract:
The blastula Chordin- and Noggin-expressing (BCNE) center located in the dorsal animal region of the Xenopus blastula embryo...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, Robertis EM, Kuroda H. Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mech Dev. 2008 Jan-Feb;125(1-2):58-66. Epub 2007 Oct 12.

Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity

Authors:
Izumi N, Helker C, Ehling M, Behrens A, Herzog W, Adams RH
Citation:
PLoS ONE. 2012;7(7):e41116. doi:10.1371/journal.pone.0041116
Epub:
Not Epub
Abstract:
Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Izumi N, Helker C, Ehling M, Behrens A, Herzog W, Adams RH. Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity. PLoS ONE. 2012;7(7):e41116. doi:10.1371/journal.pone.0041116.

FGF4 regulates blood and muscle specification in Xenopus laevis

Authors:
Isaacs HV, Deconinck AE, Pownall ME
Citation:
Biol Cell. 2007 Mar;99(3):165-73
Epub:
Not Epub
Abstract:
Background information: FGF signaling is known to be required for many aspects of mesoderm formation and patterning during...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Isaacs HV, Deconinck AE, Pownall ME. FGF4 regulates blood and muscle specification in Xenopus laevis. Biol Cell. 2007 Mar;99(3):165-73.

Gene silencing of CD47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: Implications for human disease.

Authors:
Isenberg JS, Romeo MJ, Maxhimer JB, Smedley J, Frazier WA, Roberts DD
Citation:
Ann. Surg. 247(5):860-868, 2008.
Epub:
Not Epub
Abstract:
BACKGROUND: Insufficient tissue perfusion underlies many acute and chronic diseases. Tissue perfusion in turn requires adequate...
Delivery Method:
in vivo: injection
Organism or Cell Type:
pig
Citation Extract:
Isenberg JS, Romeo MJ, Maxhimer JB, Smedley J, Frazier WA, Roberts DD. Gene silencing of CD47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: Implications for human disease.. Ann. Surg. 247(5):860-868, 2008..

Glucocorticoid/GR Inhibition of Surfactant Protein-A (SP-A) Gene Expression in Lung Type II Cells is Mediated by Repressive Changes in Histone Modification at the SP-A Promoter

Authors:
Islam KN, Mendelson CR
Citation:
Mol Endocrinol. 2008 Mar;22(3):585-96. Epub 2007 Dec 13
Epub:
Not Epub
Abstract:
Surfactant protein-A (SP-A) gene expression in human fetal lung type II cells is stimulated by cAMP and interleukin-1 (IL-1),...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fetal lung type II cells
Citation Extract:
Islam KN, Mendelson CR. Glucocorticoid/GR Inhibition of Surfactant Protein-A (SP-A) Gene Expression in Lung Type II Cells is Mediated by Repressive Changes in Histone Modification at the SP-A Promoter. Mol Endocrinol. 2008 Mar;22(3):585-96. Epub 2007 Dec 13.

HMGB factors are required for posterior digit development through integrating signaling pathway activities

Authors:
Itou J, Taniguchi N, Oishi I, Kawakami H, Lotz M, Kawakami Y
Citation:
Dev Dyn. 2011 May;240(5):1151-62. doi: 10.1002/dvdy.22598. Epub 2011 Mar 7
Epub:
Not Epub
Abstract:
The chromatin factors Hmgb1 and Hmgb2 have critical roles in cellular processes, including transcription and DNA modification....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Itou J, Taniguchi N, Oishi I, Kawakami H, Lotz M, Kawakami Y. HMGB factors are required for posterior digit development through integrating signaling pathway activities. Dev Dyn. 2011 May;240(5):1151-62. doi: 10.1002/dvdy.22598. Epub 2011 Mar 7.

Identification and characterization of Xenopus OMP25

Authors:
Inui M, Asashima M
Citation:
Dev Growth Differ. 2004 Oct;46(5):405-12
Epub:
Not Epub
Abstract:
This study describes the isolation of mitochondrial outer membrane protein 25 (OMP25) from Xenopus laevis and an analysis of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Inui M, Asashima M. Identification and characterization of Xenopus OMP25. Dev Growth Differ. 2004 Oct;46(5):405-12.

Identification of a primary target of thalidomide teratogenicity

Authors:
Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H
Citation:
Science. 2010 Mar 12;327(5971):1345-50
Epub:
Not Epub
Abstract:
Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was found to be teratogenic, causing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H. Identification of a primary target of thalidomide teratogenicity. Science. 2010 Mar 12;327(5971):1345-50.

In vivo Applications of Morpholino Oligonucleotides

Authors:
Isenberg JS, Frazier WA, Roberts DD
Citation:
Gene and Cell Therapy: Therapeutic Mechanisms and Strategies 3rd ed., Ed: Templeton NS; CRC Press, 2008
Epub:
Not Epub
Abstract:
Abstract not available
Citation Extract:
Isenberg JS, Frazier WA, Roberts DD. In vivo Applications of Morpholino Oligonucleotides. Gene and Cell Therapy: Therapeutic Mechanisms and Strategies 3rd ed., Ed: Templeton NS; CRC Press, 2008.

Increasing survival of ischemic tissue by targeting CD47

Authors:
Isenberg JS, Romeo MJ, Abu-Asab M, Tsokos M, Oldenborg A, Pappan L, Wink DA, Frazier WA, Roberts DD
Citation:
Circ. Res. 100:712-720, 2007
Epub:
Not Epub
Abstract:
Thrombospondin-1 (TSP1) limits the angiogenic and vasodilator activities of NO. This activity of TSP1 can be beneficial in some...
Link:
http://circres.ahajournals.org/content/100/5/712.long
Delivery Method:
in vivo: injection
Organism or Cell Type:
mice and cell culture
Citation Extract:
Isenberg JS, Romeo MJ, Abu-Asab M, Tsokos M, Oldenborg A, Pappan L, Wink DA, Frazier WA, Roberts DD. Increasing survival of ischemic tissue by targeting CD47. Circ. Res. 100:712-720, 2007.

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