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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

A male with unilateral microphthalmia reveals a role for TMX3 in eye development

Authors:
Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A
Citation:
PLoS One. 2010 May 11;5(5):e10565
Epub:
Not Epub
Abstract:
Anophthalmia and microphthalmia are important birth defects, but their pathogenesis remains incompletely understood. We studied...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A. A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One. 2010 May 11;5(5):e10565.

An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis

Authors:
Cast AE, Gao C, Amack JD, Ware SM
Citation:
Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21.
Epub:
Not Epub
Abstract:
Mutations in ZIC3 result in X-linked heterotaxy in humans, a syndrome consisting of left–right (L–R) patterning defects,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish, Xenopus
Citation Extract:
Cast AE, Gao C, Amack JD, Ware SM. An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis. Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21..

Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of VEGF-A expression and angiogenesis

Authors:
Chang SH, Lu YC, Li X, Hsieh WY, Xiong Y, Ghosh M, Evans T, Elemento O, Hla T
Citation:
J Biol Chem. 2012;[Epub ahead of print]doi:10.1074/jbc.M112.423871
Epub:
Not Epub
Abstract:
HuR, also known as Elavl1, is an RNA binding protein that regulates embryonic development, progenitor cell survival and cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang SH, Lu YC, Li X, Hsieh WY, Xiong Y, Ghosh M, Evans T, Elemento O, Hla T. Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of VEGF-A expression and angiogenesis. J Biol Chem. 2012;[Epub ahead of print]doi:10.1074/jbc.M112.423871.

Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo

Authors:
Carron C, Bourdelas A, Li HY, Boucaut JC, Shi DL
Citation:
Mech Dev. 2005 Nov;122(11):1234-47. Epub 2005 Jul 18.
Epub:
Not Epub
Abstract:
The homeobox gene Otx2 is expressed during gastrulation in the anterior domain of the vertebrate embryo and is involved in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Carron C, Bourdelas A, Li HY, Boucaut JC, Shi DL. Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo. Mech Dev. 2005 Nov;122(11):1234-47. Epub 2005 Jul 18..

Anthrax toxin receptor 2a controls mitotic spindle positioning

Authors:
Castanon I, Abrami L, Holtzer L, Heisenberg C, van der Goot FG, González-Gaitán M
Citation:
Nat Cell Biol. 2013 Jan;15(1):28-39. doi: 10.1038/ncb2632. Epub 2012 Dec 2.
Epub:
Not Epub
Abstract:
Oriented mitosis is essential during tissue morphogenesis. The Wnt/planar cell polarity (Wnt/PCP) pathway orients mitosis in a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Castanon I, Abrami L, Holtzer L, Heisenberg C, van der Goot FG, González-Gaitán M. Anthrax toxin receptor 2a controls mitotic spindle positioning. Nat Cell Biol. 2013 Jan;15(1):28-39. doi: 10.1038/ncb2632. Epub 2012 Dec 2..

aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development

Authors:
Chalmers AD, Pambos M, Mason J, Lang S, Wylie C, Papalopulu N
Citation:
Development. 2005 Mar;132(5):977-86. Epub 2005 Feb 2
Epub:
Not Epub
Abstract:
In early vertebrate development, apicobasally polarised blastomeres divide to produce inner non-polarised cells and outer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Chalmers AD, Pambos M, Mason J, Lang S, Wylie C, Papalopulu N. aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development. 2005 Mar;132(5):977-86. Epub 2005 Feb 2.

Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis

Authors:
Cau E, Wilson SW
Citation:
Development 2003 Jun;130(11):2455-66
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Floating head (Flh) is required for the generation of neurones in the zebrafish epiphysis...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cau E, Wilson SW. Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis. Development 2003 Jun;130(11):2455-66.

Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse

Authors:
Chang HY, Minahan K, Merriman JA, Jones KT
Citation:
Development. 2009 Dec;136(24):4077-81. doi: 10.1242/dev.042143. Epub 2009 Nov 11.
Epub:
Not Epub
Abstract:
Mature mammalian eggs are ovulated arrested at meiotic metaphase II. Sperm break this arrest by an oscillatory Ca(2+) signal...
Organism or Cell Type:
mouse oocytes
Citation Extract:
Chang HY, Minahan K, Merriman JA, Jones KT. Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse. Development. 2009 Dec;136(24):4077-81. doi: 10.1242/dev.042143. Epub 2009 Nov 11..

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

Authors:
Cao Y, Semanchik N, Lee SH, Somlo S, Barbano PE, Coifman R, Sun Z
Citation:
Proc Natl Acad Sci U S A. 2009;106(51):21819-24. doi:10.1073/pnas.0911987106
Epub:
Not Epub
Abstract:
Polycystic kidney disease (PKD) is a common human genetic disease with severe medical consequences. Although it is appreciated...
Organism or Cell Type:
zebrafish
Citation Extract:
Cao Y, Semanchik N, Lee SH, Somlo S, Barbano PE, Coifman R, Sun Z. Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. Proc Natl Acad Sci U S A. 2009;106(51):21819-24. doi:10.1073/pnas.0911987106.

CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors

Authors:
Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea AD
Citation:
Mol Cancer. 2009 Apr 16;8:24. doi: 10.1186/1476-4598-8-24.
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: DNA repair deficient tumor cells have been shown to accumulate high levels of DNA damage. Consequently,...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea AD. CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors. Mol Cancer. 2009 Apr 16;8:24. doi: 10.1186/1476-4598-8-24..

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