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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

Authors:
Chitramuthu BP, Baranowski DC, Kay DG, Bateman A, Bennett HP
Citation:
Mol Neurodegener. 2010 Oct 14;5(1):41. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Progranulin (PGRN) encoded by the GRN gene, is a secreted glycoprotein growth factor that has been implicated in...
Organism or Cell Type:
zebrafish
Citation Extract:
Chitramuthu BP, Baranowski DC, Kay DG, Bateman A, Bennett HP. Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1. Mol Neurodegener. 2010 Oct 14;5(1):41. [Epub ahead of print].

Progress towards a method of targeted protein knockdown in Fundulus heteroclitus

Authors:
Choe KP, Stidham J, Evans DH
Citation:
The Bulletin, MDI Biological Laboratory V. 45, 2006
Epub:
Not Epub
Abstract:
The isolated opercular epithelium of killifish, Fundulus heteroclitus, has been an electrophysiological model for elucidating...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Fundulus heteroclitus
Citation Extract:
Choe KP, Stidham J, Evans DH. Progress towards a method of targeted protein knockdown in Fundulus heteroclitus. The Bulletin, MDI Biological Laboratory V. 45, 2006.

Protocadherin-17 function in zebrafish retinal development

Authors:
Chen Y, Londraville R, Brickner S, El-Shaar L, Fankhauser K, Dearth C, Fulton L, Sochacka A, Bhattarai S, Marrs JA, Liu Q
Citation:
Dev Neurobiol. 2012 Aug 28. doi: 10.1002/dneu.22053. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cadherin cell adhesion molecules play crucial roles in vertebrate development including the development of the retina. Most...
Delivery Method:
microinjection or Vivo-Morpholino injection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y, Londraville R, Brickner S, El-Shaar L, Fankhauser K, Dearth C, Fulton L, Sochacka A, Bhattarai S, Marrs JA, Liu Q. Protocadherin-17 function in zebrafish retinal development. Dev Neurobiol. 2012 Aug 28. doi: 10.1002/dneu.22053. [Epub ahead of print].

PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish

Authors:
Chen IH, Wang HH, Hsieh YS, Huang WC, Yeh HI, Chuang YJ
Citation:
Cardiovasc Res. 2012 Dec 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
AIM: Cardiac valve disease is a common cause of congenital heart failure. Cardiac valve development requires a complex...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen IH, Wang HH, Hsieh YS, Huang WC, Yeh HI, Chuang YJ. PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish. Cardiovasc Res. 2012 Dec 4. [Epub ahead of print].

Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5

Authors:
Chen H, Contreras X, Yamaguchi Y, Handa H, Peterlin BM, Guo S
Citation:
PLoS One. 2009 Sep 9;4(9):e6918
Epub:
Not Epub
Abstract:
The stalling of RNA polymerase II (RNAPII) at the promoters of many genes, including developmental regulators, stress-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Contreras X, Yamaguchi Y, Handa H, Peterlin BM, Guo S. Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5. PLoS One. 2009 Sep 9;4(9):e6918.

Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus

Authors:
Chen Y, Pan FC, Brandes N, Afelik S, Solter M, Pieler T
Citation:
Dev Biol. 2004 Jul 1;271(1):144-60
Epub:
Not Epub
Abstract:
How and when the vertebrate endoderm is first subdivided into discrete progenitor cell populations that will give rise to the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen Y, Pan FC, Brandes N, Afelik S, Solter M, Pieler T. Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev Biol. 2004 Jul 1;271(1):144-60.

Role of Zebrafish Lbx2 in Embryonic Lateral Line Development

Authors:
Chen X, Lou Q, He J, Yin Z
Citation:
PLoS ONE. 2011;6(12): e29515. doi:10.1371/journal.pone.0029515
Epub:
Not Epub
Abstract:
Cellular functions and survival are dependent on a tightly controlled redox potential. Currently, an increasing amount of data...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Lou Q, He J, Yin Z. Role of Zebrafish Lbx2 in Embryonic Lateral Line Development. PLoS ONE. 2011;6(12): e29515. doi:10.1371/journal.pone.0029515.

Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines

Authors:
Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ
Citation:
Brain. 2009 Jun 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polypyrimidine tract-binding protein 1 (PTBP1) is a multi-functional RNA-binding protein that is aberrantly overexpressed in...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: glioma lines U 251 and LN 229
Citation Extract:
Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain. 2009 Jun 8. [Epub ahead of print].

Syndecan-2 is essential for angiogenic sprouting during zebrafish development

Authors:
Chen E, Hermanson S, Ekker SC
Citation:
Blood. 2004 Mar 1;103(5):1710-9. Epub 2003 Oct 30.
Epub:
Not Epub
Abstract:
We used a morpholino-based gene targeting screen to identify a novel protein essential for vascular development using the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen E, Hermanson S, Ekker SC. Syndecan-2 is essential for angiogenic sprouting during zebrafish development. Blood. 2004 Mar 1;103(5):1710-9. Epub 2003 Oct 30..

Synthesis and in Vitro Characterization of a Dendrimer-MORF Conjugate for Amplification Pretargeting

Authors:
Chen X, Dou S, Liu G, Liu X, Wang Y, Chen L, Rusckowski M, Hnatowich DJ
Citation:
Bioconjug Chem. 2008 Jul 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amplification pretargeting can play an important role in molecular imaging by significantly increasing the accumulation of...
Citation Extract:
Chen X, Dou S, Liu G, Liu X, Wang Y, Chen L, Rusckowski M, Hnatowich DJ. Synthesis and in Vitro Characterization of a Dendrimer-MORF Conjugate for Amplification Pretargeting. Bioconjug Chem. 2008 Jul 23. [Epub ahead of print].

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