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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11761 scientific papers returned from the database with the search filters currently being used below.

Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21

Authors:
Banjo T, Grajcarek J, Yoshino D, Osada H, Miyasaka KY, Kida YS, Ueki Y, Nagayama K, Kawakami K, Matsumoto T, Sato M, Ogura T
Citation:
Nature Comm. 2013;4:article1978 doi:10.1038/ncomms2978
Epub:
Not Epub
Abstract:
Heartbeat is required for normal development of the heart, and perturbation of intracardiac flow leads to morphological defects...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Banjo T, Grajcarek J, Yoshino D, Osada H, Miyasaka KY, Kida YS, Ueki Y, Nagayama K, Kawakami K, Matsumoto T, Sato M, Ogura T. Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature Comm. 2013;4:article1978 doi:10.1038/ncomms2978.

Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation

Authors:
Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M
Citation:
Development. 2004 Feb; 131(3): 525-537
Epub:
Not Epub
Abstract:
The large extracellular polysaccharide Hyaluronan (HA) and its synthesizing enzymes (Has) have been implicated in regulating...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M. Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development. 2004 Feb; 131(3): 525-537.

Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain.

Authors:
Barresi MJ, Hutson LD, Chien CB, Karlstrom RO.
Citation:
Development. 2005 Aug;132(16):3643-56. Epub 2005 Jul 20.
Epub:
Not Epub
Abstract:
Three major axon pathways cross the midline of the vertebrate forebrain early in embryonic development: the postoptic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Barresi MJ, Hutson LD, Chien CB, Karlstrom RO.. Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain.. Development. 2005 Aug;132(16):3643-56. Epub 2005 Jul 20..

Hoxa2 knockdown in Xenopus results in hyoid to mandibular homeosis

Authors:
Baltzinger M, Ori M, Pasqualetti M, Nardi I, Rijli FM
Citation:
Dev Dyn. 2005 Dec;234(4):858-67.
Epub:
Not Epub
Abstract:
The skeletal structures of the face and throat are derived from cranial neural crest cells (NCCs) that migrate from the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Baltzinger M, Ori M, Pasqualetti M, Nardi I, Rijli FM. Hoxa2 knockdown in Xenopus results in hyoid to mandibular homeosis. Dev Dyn. 2005 Dec;234(4):858-67..

Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish

Authors:
Becker JR, Deo RC, Werdich AA, Panàkovà D, Coy S, Macrae CA
Citation:
Dis Model Mech. 2011 Jan 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
To assess the effects during cardiac development of mutations that cause human cardiomyopathy, we modeled a sarcomeric gene...
Organism or Cell Type:
zebrafish
Citation Extract:
Becker JR, Deo RC, Werdich AA, Panàkovà D, Coy S, Macrae CA. Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech. 2011 Jan 18. [Epub ahead of print].

Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1

Authors:
Barembaum M, Bronner ME
Citation:
Dev Biol. 2013 Aug 19. doi:pii: S0012-1606(13)00421-1. 10.1016/j.ydbio.2013.08.009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neural crest cells form diverse derivatives that vary according to their level of origin along the body axis, with only cranial...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Barembaum M, Bronner ME. Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1. Dev Biol. 2013 Aug 19. doi:pii: S0012-1606(13)00421-1. 10.1016/j.ydbio.2013.08.009. [Epub ahead of print].

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy

Authors:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ
Citation:
Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29
Epub:
Not Epub
Abstract:
Jeune asphyxiating thoracic dystrophy, an autosomal recessive chondrodysplasia, often leads to death in infancy because of a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ. IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy. Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29.

In vitro organogenesis from undifferentiated cells in Xenopus

Authors:
Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T
Citation:
Dev Dyn. 2009 May 13;238(6):1309-1320. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amphibians have been used for over a century as experimental animals. In the field of developmental biology in particular, much...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T. In vitro organogenesis from undifferentiated cells in Xenopus. Dev Dyn. 2009 May 13;238(6):1309-1320. [Epub ahead of print].

In vivo genome editing using a high-efficiency TALEN system

Authors:
Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug Ii RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, Ekker SC
Citation:
Nature. 2012 Sep 23. doi: 10.1038/nature11537. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and human disease with a rich array of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug Ii RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, Ekker SC. In vivo genome editing using a high-efficiency TALEN system. Nature. 2012 Sep 23. doi: 10.1038/nature11537. [Epub ahead of print].

In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling

Authors:
Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA
Citation:
Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23
Epub:
Not Epub
Abstract:
AIMS: Despite increased understanding of the fundamental biology regulating cardiomyocyte hypertrophy and heart failure, it has...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA. In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23.

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