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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning

Authors:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV
Citation:
Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023
Epub:
Not Epub
Abstract:
The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023.

TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells

Authors:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW
Citation:
Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print]
Epub:
Yes
Abstract:
PSF (a.k.a. SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repair and RNA...
Organism or Cell Type:
cell culture: JSL1 cells
Citation Extract:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print].

Luminal signalling links cell communication to tissue architecture during organogenesis

Authors:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D
Citation:
Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22
Epub:
Not Epub
Abstract:
Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing...
Citation Extract:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D. Luminal signalling links cell communication to tissue architecture during organogenesis. Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22.

Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy

Authors:
Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin LB, Francescatto L, Ozes B, Karaca E, Jhangiani SN, Bainbridge MN, Lawson KS, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer PJ, Goksungur MT, Shy M, Crawford TO, Koenig M, Willer J, Flores BN, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny DM; Baylor-Hopkins Center for Mendelian Genomics, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs RA, Lupski JR
Citation:
Cell Rep. 2015 Aug 18;12(7):1169-83. doi: 10.1016/j.celrep.2015.07.023. Epub 2015 Aug 6
Epub:
Not Epub
Abstract:
Charcot-Marie-Tooth (CMT) disease is a clinically and genetically heterogeneous distal symmetric polyneuropathy. Whole-exome...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin LB, Francescatto L, Ozes B, Karaca E, Jhangiani SN, Bainbridge MN, Lawson KS, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer PJ, Goksungur MT, Shy M, Crawford TO, Koenig M, Willer J, Flores BN, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny DM; Baylor-Hopkins Center for Mendelian Genomics, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs RA, Lupski JR. Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18;12(7):1169-83. doi: 10.1016/j.celrep.2015.07.023. Epub 2015 Aug 6.

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence

Authors:
Li C, Lan Y, Schwartz-Orbach L, Korol E, Tahiliani M, Evans T, Goll MG
Citation:
Cell Rep. 2015 Aug 18;12(7):1133-43. doi: 10.1016/j.celrep.2015.07.025. Epub 2015 Aug 6
Epub:
Not Epub
Abstract:
The Tet family of methylcytosine dioxygenases (Tet1, Tet2, and Tet3) convert 5-methylcytosine to 5-hydroxymethylcytosine. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li C, Lan Y, Schwartz-Orbach L, Korol E, Tahiliani M, Evans T, Goll MG. Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 2015 Aug 18;12(7):1133-43. doi: 10.1016/j.celrep.2015.07.025. Epub 2015 Aug 6.

Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change

Authors:
Sakamaki K, Iwabe N, Iwata H, Imai K, Takagi C, Chiba K, Shukunami C, Tomii K, Ueno N
Citation:
Biochem Biophys Rep. 2015;[Epub ahead of print] doi:10.1016/j.bbrep.2015.08.005
Epub:
Yes
Abstract:
Cellular FLICE-like inhibitory protein (c-FLIP, gene symbol CFLAR) was first identified as a negative regulator of death...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sakamaki K, Iwabe N, Iwata H, Imai K, Takagi C, Chiba K, Shukunami C, Tomii K, Ueno N. Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change. Biochem Biophys Rep. 2015;[Epub ahead of print] doi:10.1016/j.bbrep.2015.08.005.

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model

Authors:
Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O'Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J
Citation:
PLoS One. 2015 Aug 7;10(8):e0135340. doi: 10.1371/journal.pone.0135340. eCollection 2015
Epub:
Not Epub
Abstract:
Trichomonas vaginalis causes vaginitis and increases the risk of HIV transmission by heterosexual sex, while Tritrichomonas...
Delivery Method:
electroporation
Organism or Cell Type:
Trichomonas vaginalis
Citation Extract:
Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O'Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J. Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model. PLoS One. 2015 Aug 7;10(8):e0135340. doi: 10.1371/journal.pone.0135340. eCollection 2015.

Receptor interacting protein 3-induced RGC-5 cell necroptosis following oxygen glucose deprivation

Authors:
Ding W, Shang L, Huang JF, Li N, Chen D, Xue LX, Xiong K
Citation:
BMC Neurosci. 2015 Aug 4;16(1):49. doi: 10.1186/s12868-015-0187-x
Epub:
Not Epub
Abstract:
BACKGROUND: Necroptosis is a type of regulated form of cell death that has been implicated in the pathogenesis of various...
Delivery Method:
cell bathing
Organism or Cell Type:
cell culture: mouse RGC-5
Citation Extract:
Ding W, Shang L, Huang JF, Li N, Chen D, Xue LX, Xiong K. Receptor interacting protein 3-induced RGC-5 cell necroptosis following oxygen glucose deprivation. BMC Neurosci. 2015 Aug 4;16(1):49. doi: 10.1186/s12868-015-0187-x.

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

Authors:
Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA
Citation:
Nat Med. 2015 Sep;21(9):989-97. doi: 10.1038/nm.3901. Epub 2015 Aug 3
Epub:
Not Epub
Abstract:
Progressive kidney fibrosis contributes greatly to end-stage renal failure, and no specific treatment is available to preserve...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA. Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Nat Med. 2015 Sep;21(9):989-97. doi: 10.1038/nm.3901. Epub 2015 Aug 3.

Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation

Authors:
Simões-Costa M, Stone M, Bronner ME
Citation:
Dev Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are induced at the neural plate border by the combined action of transcription factors and signaling...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Simões-Costa M, Stone M, Bronner ME. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Dev Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024. [Epub ahead of print].

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