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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis
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Citation:
Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: During primitive hematopoiesis in Xenopus, cebpa and spib expressing myeloid cells emerge from the anterior ventral... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Agricola ZN, Jagpal AK, Allbee AW, Prewitt AR, Shifley ET, Rankin SA, Zorn AM, Kenny AP. Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis. Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print]. |
Mutations in DCHS1 cause mitral valve prolapse
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Citation:
Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10 Epub:
Not Epub Abstract:
Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 individuals. It can manifest as... Organism or Cell Type:
zebrafish Citation Extract: Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA. Mutations in DCHS1 cause mitral valve prolapse. Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10. |
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
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Citation:
Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print] Epub:
Yes Abstract:
N-terminal acetylation, catalyzed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ree RM, Myklebust LM, Thiel P, Foyn H, Fladmark KE, Arnesen T. The N-terminal acetyltransferase Naa10 is essential for zebrafish development. Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print]. |
Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis
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Citation:
Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4 Epub:
Not Epub Abstract:
Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW. Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4. |
Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces
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Citation:
Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30 Epub:
Not Epub Abstract:
Contact inhibition of locomotion (CIL) is the process through which cells move away from each other after cell-cell contact,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R. Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces. Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30. |
Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution
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Citation:
BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x Epub:
Not Epub Abstract:
BACKGROUND: The functional consequences of whole genome duplications in vertebrate evolution are not fully understood. It... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW. Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution. BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x. |
Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome
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Citation:
Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4 Epub:
Not Epub Abstract:
Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM. Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4. |
Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos
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Citation:
PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015 Epub:
Not Epub Abstract:
DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu Z, Holzschuh J, Driever W. Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos. PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015. |
Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response
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Citation:
Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print] Epub:
Yes Abstract:
The human SMN2 transgenic mice are well-established models of spinal muscular atrophy (SMA). While the severe type I mouse... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Zhou H, Meng J, Marrosu E, Janghra N, Morgan J, Muntoni F. Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response. Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print]. |
Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models
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Citation:
Sci Rep. 2015;5:12727 doi:10.1038/srep12727 Epub:
Not Epub Abstract:
Chikungunya virus (CHIKV) infection in human is associated with debilitating and persistent arthralgia and arthritis. Currently... Delivery Method:
Endo-Porter(cultures) and Vivo-Morpholino(mice) Organism or Cell Type:
cell culture: HeLa, BHK, C6/36(mosquito) and mice Citation Extract: Lam S, Chen H, Chen CK, Min N, Chu JJH. Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models. Sci Rep. 2015;5:12727 doi:10.1038/srep12727. |