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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish
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Citation:
Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print] Epub:
Yes Abstract:
Angiogenesis is an essential requirement for embryonic development and adult homeostasis. Its deregulation is a key feature of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kamaid A, Molina-Villa T, Mendoza V, Pujades C, Maldonado E, Ispizua Belmonte JC, López-Casillas F. Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish. Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print]. |
Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae
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Citation:
FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print] Epub:
Yes Abstract:
The central melanocortin system is a key regulator of energy homeostasis. Recent studies indicate that tankyrases (TNKSs),... Organism or Cell Type:
zebrafish Citation Extract: Wang H, Semenova S, Kuusela S, Panula P, Lehtonen S. Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae. FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print]. |
Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation
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Citation:
Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274 Epub:
Yes Abstract:
LINC-HELLP, showing chromosomal linkage with the pregnancy-specific HELLP-syndrome in Dutch families, reduces differentiation... Citation Extract: van Dijk M, Visser A, Buabeng KML, Poutsma A, van der Schors RC, Oudejans CBM. Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation. Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274. |
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
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Citation:
Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201 Epub:
Yes Abstract:
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201. |
Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model
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Citation:
Sci Rep. 2015;5:10351. doi:10.1038/srep10351 Epub:
Not Epub Abstract:
Retinoblastoma is a highly invasive malignant tumor that often invades the brain and metastasizes to distal organs through the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y. Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model. Sci Rep. 2015;5:10351. doi:10.1038/srep10351. |
Identification of Polycystin-2 and CFTR common targets
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Citation:
Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4 Epub:
Not Epub Abstract:
Poster From Cilia 2014 Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roxo-Rosa M, Lopes SS. Identification of Polycystin-2 and CFTR common targets. Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4. |
Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder
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Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354 Epub:
Yes Abstract:
Dominant optic atrophy (DOA) and axonal peripheral neuropathy (Charcot-Marie-Tooth type 2, or CMT2) are hereditary... Organism or Cell Type:
zebrafish Citation Extract: Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schüle R, Caporali L, La Morgia C, Maresca A, Liguori R, Lodi R, Ahmed ZM, Sund KL, Wang X, Krueger LA, Peng Y, Prada CE, Prows CA, Schorry EK, Antonellis A, Zimmerman HH, Abdul-Rahman OA, Yang Y, Downes SM, Prince J, Fontanesi F, Barrientos A, Németh AH, Carelli V, Huang T, Zuchner S, Dallman JE. Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354. |
The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier
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Citation:
Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print] Epub:
Yes Abstract:
Podocyte dysfunction impairs the size selectivity of the glomerular filter, leading to proteinuria, hypoalbuminuria, and edema... Organism or Cell Type:
zebrafish Citation Extract: Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J. The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print]. |
Genetic compensation induced by deleterious mutations but not gene knockdowns
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Citation:
Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13 Epub:
Yes Abstract:
Cells sense their environment and adapt to it by fine-tuning their transcriptome. Wired into this network of gene expression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossi A, Kontarakis Z, Gerri C, Nolte H, Hölper S, Krüger M, Stainier DYR. Genetic compensation induced by deleterious mutations but not gene knockdowns. Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13. |
Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish
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Citation:
PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908 Epub:
Not Epub Abstract:
Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seiler C, Gebhart N, Zhang Y, Shinton SA, Li Y-s, Ross NL, Liu X, Li Q, Bilbee AN, Varshney GK, LaFave MC, Burgess SM, Balciuniene J, Balciunas D, Hardy RR, Kappes DJ, Wiest DL, Rhodes J. Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908. |