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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation
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Citation:
Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print Epub:
Not Epub Abstract:
Cell and tissue reshaping is crucial for coordinating three-dimensional pattern formation, in which the size and shape of the... Delivery Method:
microinjection Organism or Cell Type:
Ciona savignyi (ascidian) Citation Extract: Peng H, Qiao J, Wang G, Shi W, Xia F, Qiao R, Dong B. A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation. Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print. |
mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates
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Citation:
Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are a special type of antisense oligonucleotides (ASOs) that can be used as... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa; mice Citation Extract: Lessl AL, Pöhmerer J, Lin Y, Wilk U, Höhn M, Hörterer E, Wagner E, Lächelt U. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates. Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print. |
Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology
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Citation:
J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208 Epub:
Not Epub Abstract:
Undesired maturation and reproduction are major challenges in fish aquaculture regarding genetic introgression, precocious... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Oncorhynchus kisutch (coho salmon) Citation Extract: Xu L, Zhao M, Zohar Y, Wong T-T. Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology. J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208. |
Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer
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Citation:
Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385 Epub:
Not Epub Abstract:
The surrogate broodstock technique produces donor-derived gametes via transplantation of germ cells into surrogate fish. The... Delivery Method:
microinjection Organism or Cell Type:
Takifugu alboplumbeus (grass puffer) Citation Extract: Yoshikawa H, Ino Y, Kishimoto K, Koyakumaru H, Saito T, Kinoshita M, Yoshiura Y. Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer. Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385. |
UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice
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Citation:
Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print Epub:
Yes Abstract:
This study aimed to investigate the induction of mild unconjugated hyperbilirubinemia in hepatic UGT1A1 inhibition by... Delivery Method:
intravenous (i.v.) Organism or Cell Type:
mice Citation Extract: Marghani BH, Ateya AI, Othman BH, Rizk MA, El-Adl M. UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice. Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print. |
Embryo-scale reverse genetics at single-cell resolution
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Citation:
Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print Epub:
Yes Abstract:
The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saunders LM, Srivatsan SR, Duran M, Dorrity MW, Ewing B, Linbo TH, Shendure J, Raible DW, Moens CB, Kimelman D, Trapnell C. Embryo-scale reverse genetics at single-cell resolution. Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print. |
asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function
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Citation:
Int J Mol Sci. 2023;24(22):16364. doi:10.3390/ijms242216364 Epub:
Not Epub Abstract:
Ankyrin repeat and suppression-of-cytokine-signaling box (Asb) proteins, a subset of ubiquitin ligase E3, include Asb5 with six... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cai W, Wang Y, Luo Y, Gao L, Zhang J, Jiang Z, Fan X, Li F, Xie Y, Wu X, Li Y, Yuan W. . asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function. Int J Mol Sci. 2023;24(22):16364. doi:10.3390/ijms242216364 . |
Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury
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Citation:
Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012 Epub:
Not Epub Abstract:
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of... Delivery Method:
Gelfoam at lesion Organism or Cell Type:
lamprey Citation Extract: Hu J, Zhang KG, Rodemer W, Jin L-Q, Selzer ME. Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury. Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012. |
Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer
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Citation:
Drug Deliv Transl Res. 2024 May;14(5):1352-1369. doi: 10.1007/s13346-023-01469-7. Epub 2023 Nov 17. PMID: 37978163; PMCID: PMC10984892. Epub:
Not Epub Abstract:
Antisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Previously, we have demonstrated... Delivery Method:
peptide-linked, exosome Organism or Cell Type:
cell culture: SW620, xenograft mice Citation Extract: Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X
. Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer. Drug Deliv Transl Res. 2024 May;14(5):1352-1369. doi: 10.1007/s13346-023-01469-7. Epub 2023 Nov 17. PMID: 37978163; PMCID: PMC10984892.. |
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice
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Citation:
Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1 Epub:
Not Epub Abstract:
Background: The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Hiyoshi T, Zhao F, Baba R, Hirakawa T, Kuboki R, Suzuki K, Tomimatsu Y, O'Donnell P, Han S, Zach N, Nakashima M. Electrical impedance myography detects dystrophin-related muscle changes in mdx mice. Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1. |