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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Identification of Fat Storage-Inducing Transmembrane Proteins 1 and 2 as Putative Therapeutic Targets for Heart Failure by Integrated Analysis of Proteome and Transcriptome

Authors:
Nishihama N, Abe Y, Kubota K, Nagayama T, Hirai T, Ueda K, Nakamaru K, Hirata T, Fukuda K, Koshi R, Makino S
Citation:
J Proteomics Bioinform. 2018;11:173-182. doi:10.4172/jpb.1000484
Epub:
Not Epub
Abstract:
Cardiovascular disease constitutes a major health burden globally, for which novel cardiotonic agents are still required....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishihama N, Abe Y, Kubota K, Nagayama T, Hirai T, Ueda K, Nakamaru K, Hirata T, Fukuda K, Koshi R, Makino S. Identification of Fat Storage-Inducing Transmembrane Proteins 1 and 2 as Putative Therapeutic Targets for Heart Failure by Integrated Analysis of Proteome and Transcriptome. J Proteomics Bioinform. 2018;11:173-182. doi:10.4172/jpb.1000484.

Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in zebrafish (Danio rerio)

Authors:
Ulin A, Henderson J, Pham M-T, Meyo J, Chen Y, Karchner SI, Goldstone JV, Hahn ME, Williams LM
Citation:
Toxicol Sci. 2018;kfy257 doi:10.1093/toxsci/kfy257
Epub:
Not Epub
Abstract:
Interactions between regulatory pathways allow organisms to adapt to their environment and respond to stress. One interaction...
Organism or Cell Type:
zebrafish
Citation Extract:
Ulin A, Henderson J, Pham M-T, Meyo J, Chen Y, Karchner SI, Goldstone JV, Hahn ME, Williams LM. Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in zebrafish (Danio rerio). Toxicol Sci. 2018;kfy257 doi:10.1093/toxsci/kfy257.

Zebrafish znfl1s regulate left-right asymmetry patterning through controlling the expression of fgfr1a

Authors:
Li J, Gao F, Zhao Y, He L, Huang Y, Yang X, Zhou Y, Yu L, Zhao Q, Dong X
Citation:
J Cell Physiol. 2018 Oct 14. doi: 10.1002/jcp.27564. [Epub ahead of print]
Epub:
Yes
Abstract:
Proper left-right (LR) axis establishment is critical for organogenesis in vertebrates. Previously, we reported that zinc...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Gao F, Zhao Y, He L, Huang Y, Yang X, Zhou Y, Yu L, Zhao Q, Dong X. Zebrafish znfl1s regulate left-right asymmetry patterning through controlling the expression of fgfr1a. J Cell Physiol. 2018 Oct 14. doi: 10.1002/jcp.27564. [Epub ahead of print].

Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism

Authors:
Molina-Ortiz P, Orban T, Martin M, Habets A, Dequiedt F, Schurmans S
Citation:
PLoS Genet. 2018 Jan 30;14(1):e1007195. doi: 10.1371/journal.pgen.1007195. eCollection 2018 Jan
Epub:
Not Epub
Abstract:
Rasa3 is a GTPase activating protein of the GAP1 family which targets R-Ras and Rap1. Although catalytic inactivation or...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Molina-Ortiz P, Orban T, Martin M, Habets A, Dequiedt F, Schurmans S. Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism. PLoS Genet. 2018 Jan 30;14(1):e1007195. doi: 10.1371/journal.pgen.1007195. eCollection 2018 Jan.

Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning

Authors:
Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA
Citation:
PLoS One. 2018 Jun 7;13(6):e0193889. doi: 10.1371/journal.pone.0193889. eCollection 2018
Epub:
Not Epub
Abstract:
Cyanide is a potent toxic agent, and the few available antidotes are not amenable to rapid deployment in mass exposures. As a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA. Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. PLoS One. 2018 Jun 7;13(6):e0193889. doi: 10.1371/journal.pone.0193889. eCollection 2018.

A molecular mechanism for Wnt ligand-specific signaling

Authors:
Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B
Citation:
Science. 2018 Aug 17;361(6403). pii: eaat1178. doi:10.1126/science.aat1178. Epub 2018 Jul 19
Epub:
Not Epub
Abstract:
Wnt signaling is key to many developmental, physiological, and disease processes in which cells seem able to discriminate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B. A molecular mechanism for Wnt ligand-specific signaling. Science. 2018 Aug 17;361(6403). pii: eaat1178. doi:10.1126/science.aat1178. Epub 2018 Jul 19.

Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential

Authors:
Swartz SZ, McKay LS, Su K-C, Padeganeh A, Paul S. Maddox PS, Knouse KA, Cheeseman I
Citation:
bioRXive. 2018;[Epub] doi:10.1101/433391
Epub:
Not Epub
Abstract:
Centromeres provide a robust model for epigenetic inheritance as they are specified by sequence-independent mechanisms...
Organism or Cell Type:
Patiria miniata (starfish)
Citation Extract:
Swartz SZ, McKay LS, Su K-C, Padeganeh A, Paul S. Maddox PS, Knouse KA, Cheeseman I. Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential. bioRXive. 2018;[Epub] doi:10.1101/433391.

DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring

Authors:
Santos RA, Fuertes AJC, Short G, Donohue KC, Shao H, Quintanilla J, Malakzadeh P, Cohen-Cory S
Citation:
Neural Dev. 2018 Sep 15;13(1):22. doi: 10.1186/s13064-018-0118-5
Epub:
Not Epub
Abstract:
BACKGROUND: Proper patterning of dendritic and axonal arbors is a critical step in the formation of functional neuronal...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Santos RA, Fuertes AJC, Short G, Donohue KC, Shao H, Quintanilla J, Malakzadeh P, Cohen-Cory S. DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring. Neural Dev. 2018 Sep 15;13(1):22. doi: 10.1186/s13064-018-0118-5.

Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo

Authors:
Moore C, Richens JL, Hough Y, Ucanok D, Malla S, Sang F, Chen Y, Elworthy S, Wilkinson RN, Gering M
Citation:
Blood Adv. 2018;2:2589-606. doi:10.1182/bloodadvances.2018020156
Epub:
Not Epub
Abstract:
The transcriptional repressors Gfi1(a) and Gfi1b are epigenetic regulators with unique and overlapping roles in hematopoiesis....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore C, Richens JL, Hough Y, Ucanok D, Malla S, Sang F, Chen Y, Elworthy S, Wilkinson RN, Gering M. Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo. Blood Adv. 2018;2:2589-606. doi:10.1182/bloodadvances.2018020156.

Myogenin promotes myocyte fusion to balance fibre number and size

Authors:
Ganassi M, Badodi S, Quiroga HPO, Zammit PS, Hinits Y, Hughes SM
Citation:
Nat Comm. 2018;9:4232. doi:10.1038/s41467-018-06583-6
Epub:
Not Epub
Abstract:
Each skeletal muscle acquires its unique size before birth, when terminally differentiating myocytes fuse to form a defined...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ganassi M, Badodi S, Quiroga HPO, Zammit PS, Hinits Y, Hughes SM. Myogenin promotes myocyte fusion to balance fibre number and size. Nat Comm. 2018;9:4232. doi:10.1038/s41467-018-06583-6.

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