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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure

Authors:
Komiya Y, Bai Z, Cai N, Lou L, Al-Saadi N, Mezzacappa C, Habas R, Runnels LW
Citation:
Sci Rep. 2017;7:15623. doi:10.1038/s41598-017-15855-y
Epub:
Not Epub
Abstract:
In humans, germline mutations in Trpm6 cause autosomal dominant hypomagnesemia with secondary hypocalcemia disorder. Loss of...
Link:
https://www.nature.com/articles/s41598-017-15855-y
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Komiya Y, Bai Z, Cai N, Lou L, Al-Saadi N, Mezzacappa C, Habas R, Runnels LW. A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure. Sci Rep. 2017;7:15623. doi:10.1038/s41598-017-15855-y.

Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion

Authors:
Radhakrishnan U, Alsrhani A, Sundaramoorthi H, Khandekar G, Kashyap M, Fuchs JL, Perkins BD, Omori Y, Jagadeeswaran P
Citation:
Platelets. 2017 Nov 10:1-10. doi: 10.1080/09537104.2017.1361524. [Epub ahead of print]
Epub:
Yes
Abstract:
Intraflagellar transport (IFT) proteins are vital for the genesis and maintenance of cilia. Our identification of ift122...
Link:
http://www.tandfonline.com/doi/abs/10.1080/09537104.2017.1361524?journalCode=iplt20
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Radhakrishnan U, Alsrhani A, Sundaramoorthi H, Khandekar G, Kashyap M, Fuchs JL, Perkins BD, Omori Y, Jagadeeswaran P. Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion. Platelets. 2017 Nov 10:1-10. doi: 10.1080/09537104.2017.1361524. [Epub ahead of print].

Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration

Authors:
Louie KW, Saera-Vila A, Kish PE, Colacino JA, Kahana A
Citation:
BMC Genomics. 2017 Nov 9;18(1):854. doi: 10.1186/s12864-017-4236-y
Epub:
Not Epub
Abstract:
BACKGROUND: Tissue regeneration requires a series of steps, beginning with generation of the necessary cell mass, followed by...
Link:
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-017-4236-y
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Louie KW, Saera-Vila A, Kish PE, Colacino JA, Kahana A. Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration. BMC Genomics. 2017 Nov 9;18(1):854. doi: 10.1186/s12864-017-4236-y.

Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood

Authors:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ
Citation:
Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17
Epub:
Not Epub
Abstract:
Staphylococcus aureus is a human commensal but also has devastating potential as an opportunistic pathogen. S. aureus...
Link:
http://iai.asm.org/content/85/11/e00337-17.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ. Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood. Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17.

Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury

Authors:
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, Alpini G, Meng F
Citation:
Am J. Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.08.027
Epub:
Yes
Abstract:
Alcoholic liver disease remains a major cause of liver-related morbidity and mortality, which ranges from alcoholic...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30583-7/fulltext
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, Alpini G, Meng F. Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury. Am J. Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.08.027.

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

Authors:
Lagendijk AK, Gomez GA, Baek S, DHesselson D, Hughes WE, Paterson S, Conway DE, Belting H-G, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM
Citation:
Nat Comm. 2017;8:1402. doi:10.1038/s41467-017-01325-6
Epub:
Not Epub
Abstract:
Forces play diverse roles in vascular development, homeostasis and disease. VE-cadherin at endothelial cell-cell junctions...
Link:
https://www.nature.com/articles/s41467-017-01325-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lagendijk AK, Gomez GA, Baek S, DHesselson D, Hughes WE, Paterson S, Conway DE, Belting H-G, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM. Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nat Comm. 2017;8:1402. doi:10.1038/s41467-017-01325-6.

Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies

Authors:
Ryan R, Failler M, Reilly ML, Garfa-Traore M, Delous M, Filhol E, Reboul T, Bole-Feysot C, Nitschké P, Baudouin V, Amselem S, Escudier E, Legendre M, Benmerah A, Saunier S
Citation:
Hum Mol Genet. 2017 Nov 7. doi: 10.1093/hmg/ddx396. [Epub ahead of print]
Epub:
Yes
Abstract:
A child presenting with Mainzer-Saldino syndrome (MZSDS), characterized by renal, retinal and skeletal involvements, was also...
Link:
https://academic.oup.com/hmg/article/doi/10.1093/hmg/ddx396/4600050
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ryan R, Failler M, Reilly ML, Garfa-Traore M, Delous M, Filhol E, Reboul T, Bole-Feysot C, Nitschké P, Baudouin V, Amselem S, Escudier E, Legendre M, Benmerah A, Saunier S. Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies. Hum Mol Genet. 2017 Nov 7. doi: 10.1093/hmg/ddx396. [Epub ahead of print].

Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish

Authors:
Kwong EML, Ho JCH, Lau MCC, You M-S, Jiang Y-J, Tse WKF
Citation:
Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.10.004
Epub:
Yes
Abstract:
Treacher Collins Syndrome (TCS) is a rare congenital birth disorder (1 in 50,000 live births) characterized by severe...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30599-0/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong EML, Ho JCH, Lau MCC, You M-S, Jiang Y-J, Tse WKF. Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.10.004.

bmp3 is required for integrity of blood brain barrier by promoting pericyte coverage in zebrafish embryos

Authors:
Lei D, Jin X, Wen L, Dai H, Ye Z, Wang G
Citation:
Curr Mol Med. 2017 Nov 5. doi: 10.2174/1566524017666171106114234. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: The compromise of blood brain barrier (BBB) integrity is often associated with human hemorrhage stroke and...
Link:
http://www.eurekaselect.com/156823
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lei D, Jin X, Wen L, Dai H, Ye Z, Wang G. bmp3 is required for integrity of blood brain barrier by promoting pericyte coverage in zebrafish embryos. Curr Mol Med. 2017 Nov 5. doi: 10.2174/1566524017666171106114234. [Epub ahead of print].

Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: fibrillar fibronectin and tissue boundary establishment in the dorsal margin

Authors:
Forecki J, Van Antwerp DJ, Lujan SM, Merzdorf CS
Citation:
Dev Biol. 2017 Nov 4. pii: S0012-1606(17)30026-X. doi: 10.1016/j.ydbio.2017.11.001. [Epub ahead of print]
Epub:
Yes
Abstract:
Aquaporins and aquaglyceroporins are a large family of membrane channel proteins that allow rapid movement of water and small,...
Link:
http://www.sciencedirect.com/science/article/pii/S001216061730026X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Forecki J, Van Antwerp DJ, Lujan SM, Merzdorf CS. Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: fibrillar fibronectin and tissue boundary establishment in the dorsal margin. Dev Biol. 2017 Nov 4. pii: S0012-1606(17)30026-X. doi: 10.1016/j.ydbio.2017.11.001. [Epub ahead of print].

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