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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency

Authors:
Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, Simon L, Müller NS, Straub T, Brooks KE, Chavez SL, Enard W, Theis FJ, Drukker M
Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114
Epub:
Yes
Abstract:
To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with...
Link:
http://www.pnas.org/content/early/2017/10/24/1708341114.full
Delivery Method:
microinjection
Organism or Cell Type:
Rhesus macaque (monkey)
Citation Extract:
Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, Simon L, Müller NS, Straub T, Brooks KE, Chavez SL, Enard W, Theis FJ, Drukker M. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114.

The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle

Authors:
Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EMD, Conti M
Citation:
Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3
Epub:
Not Epub
Abstract:
Control of protein turnover is critical for meiotic progression. Using RiboTag immunoprecipitation, RNA binding protein...
Link:
https://www.nature.com/articles/s41598-017-13688-3
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EMD, Conti M. The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle. Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3.

In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology

Authors:
Bernabo P, Tebaldi T, Groen EJN, Lane FM, Perenthaler E, Mattedi F, Newbery HJ, Zhou H, Zuccotti P, Potrich V, Shorrock HK, Muntoni F, Quattrone A, Gillingwater TH, Viero G
Citation:
Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010
Epub:
Not Epub
Abstract:
Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)31427-4
Delivery Method:
i.v. injection
Organism or Cell Type:
mice
Citation Extract:
Bernabo P, Tebaldi T, Groen EJN, Lane FM, Perenthaler E, Mattedi F, Newbery HJ, Zhou H, Zuccotti P, Potrich V, Shorrock HK, Muntoni F, Quattrone A, Gillingwater TH, Viero G. In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology. Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010.

Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence

Authors:
de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA
Citation:
PNAS USA. 2017;114(43):E8996-E9005 doi:10.1073/pnas.1708725114
Epub:
Not Epub
Abstract:
Tissue regeneration depends on the timely activation of adult stem cells. In skeletal muscle, the adult stem cells maintain a...
Link:
http://www.pnas.org/content/114/43/E8996.abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA. Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. PNAS USA. 2017;114(43):E8996-E9005 doi:10.1073/pnas.1708725114.

Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway

Authors:
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M
Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1712560114
Epub:
Yes
Abstract:
Persistent directional cell migration is involved in animal development and diseases. The small GTPase Rac1 is involved in F-...
Link:
http://www.pnas.org/content/early/2017/10/12/1712560114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1712560114.

Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming

Authors:
Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR
Citation:
BioRxiv. 2017;[preprint] doi:10.1101/204792
Epub:
Not Epub
Abstract:
The fate and function of epigenetic marks during the germline-to-embryo transition is a key issue in developmental biology,...
Link:
https://www.biorxiv.org/content/early/2017/10/17/204792
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR. Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming. BioRxiv. 2017;[preprint] doi:10.1101/204792 .

PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation

Authors:
Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH
Citation:
Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest (NC) specification comprises an early phase, initiating immature NC progenitors formation at neural plate stage,...
Link:
http://dev.biologists.org/content/early/2017/10/13/dev.157644
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH. PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation. Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print].

Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development

Authors:
Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J
Citation:
Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3
Epub:
Not Epub
Abstract:
Fishes rely on both chemical and tactile senses to orient themselves to avoid predators, and to detect and taste food. This is...
Link:
https://www.nature.com/articles/s41598-017-14042-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J. Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development. Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3.

CD146 is essential for PDGFRβ-induced pericyte recruitment

Authors:
Chen J, Luo Y, Huang H, Wu S, Feng J, Zhang J, Yan X
Citation:
Protein Cell. 2017. doi:10.1007/s13238-017-0484-5
Epub:
Not Epub
Abstract:
No abstract available.
Link:
https://link.springer.com/article/10.1007/s13238-017-0484-5#enumeration
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Luo Y, Huang H, Wu S, Feng J, Zhang J, Yan X. CD146 is essential for PDGFRβ-induced pericyte recruitment. Protein Cell. 2017. doi:10.1007/s13238-017-0484-5.

WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome

Authors:
Kim Y-J, Osborn D, Lee J-Y, Araki M, Araki K, Mohun T, Kansakoski JEM, Brandstack N, Kim H-T, Miralles F, Kim C-H, Brown NA, Kim H-G, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim S-H
Citation:
bioRxiv. 2017;[preprint] doi: https://doi.org/10.1101/200154
Epub:
Not Epub
Abstract:
WDR11 has been implicated in congenital hypogonadotropic hypogonadism (CHH) and Kallmann syndrome (KS), human developmental...
Link:
https://www.biorxiv.org/content/early/2017/10/10/200154
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim Y-J, Osborn D, Lee J-Y, Araki M, Araki K, Mohun T, Kansakoski JEM, Brandstack N, Kim H-T, Miralles F, Kim C-H, Brown NA, Kim H-G, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim S-H. WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. bioRxiv. 2017;[preprint] doi: https://doi.org/10.1101/200154.

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