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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes
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Citation:
Dev Biol. 2017 Sep 22. pii: S0012-1606(17)30412-8. doi: 10.1016/j.ydbio.2017.09.027. [Epub ahead of print] Epub:
Yes Abstract:
The transcription factor Six1 and its cofactor Eya1 are important regulators of neurogenesis in cranial placodes, activating... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Riddiford N, Schlosser G. Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes. Dev Biol. 2017 Sep 22. pii: S0012-1606(17)30412-8. doi: 10.1016/j.ydbio.2017.09.027. [Epub ahead of print]. |
LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells
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Citation:
BMB Rep. 2017 Sep 26. pii: 3929. [Epub ahead of print] Epub:
Yes Abstract:
Delta-like ligand 4 (DLL4) expression in endothelial cells is intimately associated with angiogenic sprouting and vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Choi HJ, Rho SS, Choi DH, Kwon YG. LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells. BMB Rep. 2017 Sep 26. pii: 3929. [Epub ahead of print]. |
Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis
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Citation:
Blood. 2017;[Epub ahead of print] doi:10.1182/blood-2017-05-783043 Epub:
Yes Abstract:
Congenital hypothyroidism (CH) is one of the most prevalent endocrine diseases and is often accompanied by anemia and... Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Xue Y, Cao C, Huang J, Hong Q, Hai T, Jia Q, Wang X, Qin G, Yao J, Wang X, Zheng Q, Zhang R, Li Y, Luo A, Zhang N, Shi Q, Wang Y, Ying H, Liu Z, Wang H, Meng A, Zhou Q, Wei H, Liu F, Zhao J. Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis. Blood. 2017;[Epub ahead of print] doi:10.1182/blood-2017-05-783043. |
Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model
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Citation:
Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075 Epub:
Yes Abstract:
The protein bcl-xL is able to enhance the secretion of the pro-inflammatory chemokine interleukin 8 (CXCL8) in human melanoma... Organism or Cell Type:
zebrafish Citation Extract: Gabellini C, Gómez-Abenza E, Ibáñez-Molero S, Tupone MG, Pérez-Oliva AB, de Oliveira S, Del Bufalo D, Mulero V. Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model. Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075. |
Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
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Citation:
Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3 Epub:
Not Epub Abstract:
A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sister chromatids together, first... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: El Yakoubi W, Buffin E, Cladière D, Gryaznova Y, Berengue I, Touati SA, Gómez R, Suja JA, van Deursen JM, Wassmann K. Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I. Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3. |
Bacterial DnaB helicase interacts with the excluded strand to regulate unwinding
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Citation:
J Biol Chem. 2017 Sep 22. pii: jbc.M117.814178. doi: 10.1074/jbc.M117.814178. [Epub ahead of print] Epub:
Yes Abstract:
Replicative hexameric helicases are thought to unwind duplex DNA by steric exclusion (SE), where one DNA strand is encircled by... Citation Extract: Carney SM, Gomathinayagam S, Leuba SH, Trakselis MA. Bacterial DnaB helicase interacts with the excluded strand to regulate unwinding. J Biol Chem. 2017 Sep 22. pii: jbc.M117.814178. doi: 10.1074/jbc.M117.814178. [Epub ahead of print]. |
Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis
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Citation:
Nucleic Acids Res. 2017 Sep 19;45(16):9388-9397. doi: 10.1093/nar/gkx563 Epub:
Not Epub Abstract:
Sister chromatid cohesion, mediated by cohesin complex and established by the acetyltransferases Esco1 and Esco2, is essential... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Lu Y, Dai X, Zhang M, Miao Y, Zhou C, Cui Z, Xiong B. Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis. Nucleic Acids Res. 2017 Sep 19;45(16):9388-9397. doi: 10.1093/nar/gkx563. |
Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation
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Citation:
Br J Clin Pharmacol. 2017 Sep 20. doi: 10.1111/bcp.13405. [Epub ahead of print] Epub:
Yes Abstract:
AIMS: The aims of the present study were to assess the safety, tolerability and pharmacokinetics of radavirsen following single... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Beigel JH, Voell J, Muñoz P, Kumar P, Brooks KM, Zhang J, Iversen P, Heald A, Wong M, Davey RT. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation. Br J Clin Pharmacol. 2017 Sep 20. doi: 10.1111/bcp.13405. [Epub ahead of print]. |
The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development
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Citation:
Exp Neurol. 2017 Sep 16. pii: S0014-4886(17)30239-X. doi: 10.1016/j.expneurol.2017.09.009. [Epub ahead of print] Review Epub:
Yes Abstract:
Macrophage migration inhibitory factor (MIF) is a neurotrophic cytokine essential for inner ear hair cell (HC) development and... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Weber LJ, Marcy HK, Shen YC, Tomkovich SE, Brooks KM, Hilk KE, Barald KF. The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development. Exp Neurol. 2017 Sep 16. pii: S0014-4886(17)30239-X. doi: 10.1016/j.expneurol.2017.09.009. [Epub ahead of print] Review. |
Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin
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Citation:
Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print] Epub:
Yes Abstract:
Germ-layer formation during gastrulation is both a fundamental step of development and a paradigm for tissue formation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Giger FA, David NB. Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin. Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print]. |