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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

SDS-PAGE Procedure: Application for Characterization of New Entirely Uncharged Nucleic Acids Analogues

Authors:
Pavlova AS, Dyudeeva ES, Kupryushkin MS, Amirkhanov NV, Pyshnyi DV, Pyshnaya IA
Citation:
Electrophoresis. 2017 Nov 7. doi: 10.1002/elps.201700415. [Epub ahead of print]
Epub:
Yes
Abstract:
SDS-PAGE is considered to be a universal method for size-based separation and analysis of proteins. In this study, we applied...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/elps.201700415/abstract
Citation Extract:
Pavlova AS, Dyudeeva ES, Kupryushkin MS, Amirkhanov NV, Pyshnyi DV, Pyshnaya IA. SDS-PAGE Procedure: Application for Characterization of New Entirely Uncharged Nucleic Acids Analogues. Electrophoresis. 2017 Nov 7. doi: 10.1002/elps.201700415. [Epub ahead of print].

Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish

Authors:
Cheng X-N, Shao M, Li J-T, Wang Y-F, Qi J, Xu Z-G, Shi D-L
Citation:
Nat Comm. 2017;8:1353. doi:10.1038/s41467-017-01552-x
Epub:
Not Epub
Abstract:
Gastrulation is a fundamental morphogenetic event that requires polarised cell behaviours for coordinated asymmetric cell...
Link:
https://www.nature.com/articles/s41467-017-01552-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng X-N, Shao M, Li J-T, Wang Y-F, Qi J, Xu Z-G, Shi D-L. Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish. Nat Comm. 2017;8:1353. doi:10.1038/s41467-017-01552-x.

MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli

Authors:
Daly SM, Sturge CR, Felder-Scott CF, Geller BL, Greenberg DE
Citation:
mBio. 2017;8:e01315-17. doi:10.1128/mBio.01315-17
Epub:
Not Epub
Abstract:
In late 2015, the first example of a transferrable polymyxin resistance mechanism in Gram-negative pathogens, MCR-1, was...
Link:
http://mbio.asm.org/content/8/6/e01315-17.short
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, Escherichia coli
Citation Extract:
Daly SM, Sturge CR, Felder-Scott CF, Geller BL, Greenberg DE. MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli. mBio. 2017;8:e01315-17. doi:10.1128/mBio.01315-17.

Functional analysis of the cfdp1 gene in zebrafish provides evidence for its crucial role in craniofacial development and osteogenesis

Authors:
Celauro E, Carra S, Rodriguez A, Cotelli F, Dimitri P
Citation:
Exp Cell Res. 2017 Oct 26. pii: S0014-4827(17)30570-0. doi: 10.1016/j.yexcr.2017.10.022. [Epub ahead of print]
Epub:
Yes
Abstract:
The CFDP1 proteins have been linked to craniofacial development and osteogenesis in vertebrates, though specific human...
Link:
http://www.sciencedirect.com/science/article/pii/S0014482717305700
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Celauro E, Carra S, Rodriguez A, Cotelli F, Dimitri P. Functional analysis of the cfdp1 gene in zebrafish provides evidence for its crucial role in craniofacial development and osteogenesis. Exp Cell Res. 2017 Oct 26. pii: S0014-4827(17)30570-0. doi: 10.1016/j.yexcr.2017.10.022. [Epub ahead of print].

Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

Authors:
Brennan JJ, Messerschmidt JL, Williams LM, Matthews BJ, Reynoso M, Gilmore TD
Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1711530114
Epub:
Yes
Abstract:
In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream...
Link:
http://www.pnas.org/content/early/2017/11/03/1711530114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Brennan JJ, Messerschmidt JL, Williams LM, Matthews BJ, Reynoso M, Gilmore TD. Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1711530114 .

Spindle asymmetry drives non-Mendelian chromosome segregation

Authors:
Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA
Citation:
Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092
Epub:
Not Epub
Abstract:
Genetic elements compete for transmission through meiosis, when haploid gametes are created from a diploid parent. Selfish...
Link:
http://science.sciencemag.org/content/358/6363/668
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA. Spindle asymmetry drives non-Mendelian chromosome segregation. Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092.

Frizzled-7 is required for Xenopus heart development

Authors:
Abu-Elmagd M, Mulvaney J, Wheeler GN
Citation:
Biol Open. 2017 Nov 3. pii: bio.026963. doi: 10.1242/bio.026963. [Epub ahead of print]
Epub:
Yes
Abstract:
Wnt signalling regulates cardiogenesis during specification of heart tissue and the morphogenetic movements necessary to form...
Link:
http://bio.biologists.org/content/early/2017/11/02/bio.026963.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abu-Elmagd M, Mulvaney J, Wheeler GN. Frizzled-7 is required for Xenopus heart development. Biol Open. 2017 Nov 3. pii: bio.026963. doi: 10.1242/bio.026963. [Epub ahead of print].

Profilin 1 plays feedback role in actin-mediated polar body extrusion in mouse oocytes

Authors:
Liu J, Wang QC, Duan X, Cui XS, Kim NH, Zhang Y, Sun SC
Citation:
Reprod Fertil Dev. 2017 Nov 3. doi: 10.1071/RD17354. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocytes undergo several crucial processes during meiosis maturation, including spindle formation and migration and...
Link:
http://www.publish.csiro.au/RD/RD17354
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Liu J, Wang QC, Duan X, Cui XS, Kim NH, Zhang Y, Sun SC. Profilin 1 plays feedback role in actin-mediated polar body extrusion in mouse oocytes. Reprod Fertil Dev. 2017 Nov 3. doi: 10.1071/RD17354. [Epub ahead of print].

Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease

Authors:
Hu Z-y, Chen B, Zhang J-p, Ma Y-y
Citation:
J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795
Epub:
Not Epub
Abstract:
Parkinson's disease (PD) is one of the most epidemic neurodegenerative diseases and is characterized by movement disorders...
Link:
http://www.jbc.org/content/292/44/18062.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu Z-y, Chen B, Zhang J-p, Ma Y-y. Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease. J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795.

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

Authors:
Sanna-Cherchi S, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M, Otto EA, Sampson G, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Liu Q, Na Y-J, Goj V, Ardissino G, Gigante M, Gesualdo L, Janezcko M, Zaniew M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JAE, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Kiryluk A-M, Mane S, Goldstein DB, Lifton RP, Katsanis N, Davis EE, Gharavi AG
Citation:
Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018
Epub:
Not Epub
Abstract:
Renal agenesis and hypodysplasia (RHD) are major causes of pediatric chronic kidney disease and are highly genetically...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(17)30387-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sanna-Cherchi S, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M, Otto EA, Sampson G, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Liu Q, Na Y-J, Goj V, Ardissino G, Gigante M, Gesualdo L, Janezcko M, Zaniew M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JAE, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Kiryluk A-M, Mane S, Goldstein DB, Lifton RP, Katsanis N, Davis EE, Gharavi AG. Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations. Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018.

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