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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12237 scientific papers returned from the database with the search filters currently being used below.

Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling

Authors:
Lange M, Ohnesorge N, Hoffmann D, Rocha SF, Benedito R, Siekmann AF
Citation:
Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767
Epub:
Not Epub
Abstract:
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11238767/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lange M, Ohnesorge N, Hoffmann D, Rocha SF, Benedito R, Siekmann AF. Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767.

Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway

Authors:
Lee Y-H, Kawakami K, HuangFu W-C, Liu I-H
Citation:
PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943
Epub:
Not Epub
Abstract:
Pericellular and extracellular proteoglycans play an important role in modulating morphogen gradients and signal transductions...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230943
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee Y-H, Kawakami K, HuangFu W-C, Liu I-H. Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway. PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943.

Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish

Authors:
Wu J, Lu C, Ge S, Mei J, Li X, Guo W
Citation:
Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print]
Epub:
Yes
Abstract:
IGF2BPs, a subclass of RNA-binding proteins, regulate cellular differentiation, proliferation and migration during multiple...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0378111920303012
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu J, Lu C, Ge S, Mei J, Li X, Guo W. Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish. Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print].

NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis

Authors:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F
Citation:
Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031
Epub:
Not Epub
Abstract:
Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30345-4
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031.

Golodirsen

Authors:
The LiverTox team
Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27
Epub:
Not Epub
Abstract:
Golodirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons in the synthesis of the...
Link:
https://www.ncbi.nlm.nih.gov/books/NBK555332/
Citation Extract:
The LiverTox team. Golodirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27.

Eteplirsen

Authors:
The LiverTox team
Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27
Epub:
Not Epub
Abstract:
Eteplirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons during synthesis of the...
Link:
https://www.ncbi.nlm.nih.gov/books/NBK555333/
Citation Extract:
The LiverTox team. Eteplirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27.

EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus

Authors:
Wang X, Sun J, Wang Z, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print]
Epub:
Yes
Abstract:
Receptor tyrosine kinase EphA7 is specifically expressed in otic region in Xenopus early development. However, its role in...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X20305908?via%3Dihub
Organism or Cell Type:
Xenopus
Citation Extract:
Wang X, Sun J, Wang Z, Li C, Mao B. EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus. Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print].

Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis

Authors:
Pijuan-Sala B, Wilson NK, Xia J, Hou X, Hannah RL, Kinston S, Calero-Nieto FJ, Olivier Poirion O, Preissl S, Liu F, Göttgens B
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9
Epub:
Yes
Abstract:
During mouse embryonic development, pluripotent cells rapidly divide and diversify, yet the regulatory programs that define the...
Link:
https://www.nature.com/articles/s41556-020-0489-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pijuan-Sala B, Wilson NK, Xia J, Hou X, Hannah RL, Kinston S, Calero-Nieto FJ, Olivier Poirion O, Preissl S, Liu F, Göttgens B. Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9.

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells

Authors:
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Greig EC, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Brian J. Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0
Epub:
Yes
Abstract:
The availability of nucleotides has a direct impact on transcription. The inhibition of dihydroorotate dehydrogenase (DHODH)...
Link:
https://www.nature.com/articles/s41556-020-0493-0
Organism or Cell Type:
zebrafish
Citation Extract:
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Greig EC, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Brian J. Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0.

Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis

Authors:
Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA
Citation:
J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213
Epub:
Yes
Abstract:
In mitotic cells, DNA damage induces temporary G2 arrest via inhibitory Cdk1 phosphorylation. In contrast, fully grown G2-stage...
Link:
https://rupress.org/jcb/article-abstract/219/4/e201907213/151594/Oocytes-mount-a-noncanonical-DNA-damage-response
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA. Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis. J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213.

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