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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish

Authors:
Koltowska K, Paterson S, Bower NI, Baillie GJ, Lagendijk AK, Astin JW, Chen H, Francois M, Crosier PS, Taft RJ, Simons C, Smith KA, Hogan BM
Citation:
Genes Dev. 2015 Aug 1;29(15):1618-30. doi: 10.1101/gad.263210.115
Epub:
Not Epub
Abstract:
The lymphatic vasculature plays roles in tissue fluid balance, immune cell trafficking, fatty acid absorption, cancer...
Link:
http://genesdev.cshlp.org/content/29/15/1618.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koltowska K, Paterson S, Bower NI, Baillie GJ, Lagendijk AK, Astin JW, Chen H, Francois M, Crosier PS, Taft RJ, Simons C, Smith KA, Hogan BM. mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish. Genes Dev. 2015 Aug 1;29(15):1618-30. doi: 10.1101/gad.263210.115.

DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos

Authors:
Jacob V, Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC
Citation:
Development. 2015 Feb 1;142(3):510-21. doi: 10.1242/dev.115980. Epub 2015 Jan 6
Epub:
Not Epub
Abstract:
UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) recruits DNMT1 to hemimethylated DNA during replication and...
Link:
http://dev.biologists.org/content/142/3/510.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jacob V, Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC. DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development. 2015 Feb 1;142(3):510-21. doi: 10.1242/dev.115980. Epub 2015 Jan 6.

Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development

Authors:
Yan B, Neilson KM, Ranganathan R, Maynard T, Streit A, Moody SA
Citation:
Dev Dyn. 2015 Feb;244(2):181-210. doi: 10.1002/dvdy.24229. Epub 2014 Dec 16
Epub:
Not Epub
Abstract:
BACKGROUND: Six1 plays an important role in the development of several vertebrate organs, including cranial sensory placodes,...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24229/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yan B, Neilson KM, Ranganathan R, Maynard T, Streit A, Moody SA. Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development. Dev Dyn. 2015 Feb;244(2):181-210. doi: 10.1002/dvdy.24229. Epub 2014 Dec 16.

CNS myelination requires cytoplasmic dynein function

Authors:
Yang ML, Shin J, Kearns CA, Langworthy MM, Snell H, Walker MB, Appel B
Citation:
Dev Dyn. 2015 Feb;244(2):134-45
Epub:
Not Epub
Abstract:
BACKGROUND: Cytoplasmic dynein provides the main motor force for minus-end-directed transport of cargo on microtubules. Within...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24238/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang ML, Shin J, Kearns CA, Langworthy MM, Snell H, Walker MB, Appel B. CNS myelination requires cytoplasmic dynein function. Dev Dyn. 2015 Feb;244(2):134-45.

Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish

Authors:
Mikami S, Nakaura M, Kawahara A, Mizoguchi T, Itoh M
Citation:
Biol Open. 2015 Oct 30;4(11):1576-82. doi: 10.1242/bio.014225
Epub:
Not Epub
Abstract:
The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share...
Link:
http://bio.biologists.org/content/4/11/1576.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mikami S, Nakaura M, Kawahara A, Mizoguchi T, Itoh M. Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish. Biol Open. 2015 Oct 30;4(11):1576-82. doi: 10.1242/bio.014225.

Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis

Authors:
Delcourt N, Quevedo C, Nonne C, Fons P, O'Brien D, Loyaux D, Diez M, Autelitano F, Guillemot JC, Ferrara P, Muriana A, Callol C, Hérault JP, Herbert JM, Favre G, Bono F
Citation:
J Biol Chem. 2015 Feb 6;290(6):3405-17. doi: 10.1074/jbc.M114.618611. Epub 2014 Nov 10
Epub:
Not Epub
Abstract:
The formation of new vessels in the tumor, termed angiogenesis, is essential for primary tumor growth and facilitates tumor...
Link:
http://www.jbc.org/content/290/6/3405.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Delcourt N, Quevedo C, Nonne C, Fons P, O'Brien D, Loyaux D, Diez M, Autelitano F, Guillemot JC, Ferrara P, Muriana A, Callol C, Hérault JP, Herbert JM, Favre G, Bono F. Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis. J Biol Chem. 2015 Feb 6;290(6):3405-17. doi: 10.1074/jbc.M114.618611. Epub 2014 Nov 10.

Extracellular Thiol Isomerases and Their Role in Thrombus Formation

Authors:
Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B
Citation:
Antioxid Redox Signal. 2016 Jan 1;24(1):1-15. doi: 10.1089/ars.2015.6530. Epub 2015 Nov 18
Epub:
Not Epub
Abstract:
SIGNIFICANCE: The mammalian endoplasmic reticulum (ER) houses a large family of twenty thioredoxin-like proteins of which...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717499/
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal. 2016 Jan 1;24(1):1-15. doi: 10.1089/ars.2015.6530. Epub 2015 Nov 18.

Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission

Authors:
Chaouch A, Porcelli V, Cox D, Edvardson S, Scarcia P, De Grassi A, Pierri CL, Cossins J, Laval SH, Griffin H, Müller JS, Evangelista T, Töpf A, Abicht A, Huebner A, von der Hagen M, Bushby K, Straub V, Horvath R, Elpeleg O, Palace J, Senderek J, Beeson D, Palmieri L, Lochmüller H
Citation:
J Neuromuscul Dis. 2014;1(1):75-90
Epub:
Not Epub
Abstract:
BACKGROUND AND OBJECTIVE: Congenital myasthenic syndromes are rare inherited disorders characterized by fatigable weakness...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746751/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chaouch A, Porcelli V, Cox D, Edvardson S, Scarcia P, De Grassi A, Pierri CL, Cossins J, Laval SH, Griffin H, Müller JS, Evangelista T, Töpf A, Abicht A, Huebner A, von der Hagen M, Bushby K, Straub V, Horvath R, Elpeleg O, Palace J, Senderek J, Beeson D, Palmieri L, Lochmüller H. Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission. J Neuromuscul Dis. 2014;1(1):75-90.

Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm

Authors:
Zhou J, Wang L, Zuo M, Wang X, Ahmed ASI, Chen Q, Wang QK
Citation:
Sci Rep. 2016;6:21538 doi:10.1038/srep21538
Epub:
Not Epub
Abstract:
MOG1 was initially identified as a protein that interacts with the small GTPase Ran involved in transport of macromolecules...
Link:
http://www.nature.com/articles/srep21538
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou J, Wang L, Zuo M, Wang X, Ahmed ASI, Chen Q, Wang QK. Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm. Sci Rep. 2016;6:21538 doi:10.1038/srep21538.

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

Authors:
Miller CM, Donner AJ, Blank EE, Egger AW, Kellar BM, Østergaard ME, Seth PP, Harris EN
Citation:
Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112
Epub:
Yes
Abstract:
Phosphorothioate (PS)-modified antisense oligonucleotides (ASOs) have been extensively investigated over the past three decades...
Link:
http://nar.oxfordjournals.org/content/early/2016/02/22/nar.gkw112.full
Delivery Method:
cell bathing
Organism or Cell Type:
cell culture: Stabilin cell lines
Citation Extract:
Miller CM, Donner AJ, Blank EE, Egger AW, Kellar BM, Østergaard ME, Seth PP, Harris EN. Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver. Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112.

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