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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart
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Citation:
PLoS ONE. 2016;11(3):e0150323. doi:10.1371/journal.pone.0150323 Epub:
Not Epub Abstract:
An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hirth S, Bühler A, Bührdel JB, Rudeck S, Dahme T, Rottbauer W, Just S. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11(3):e0150323. doi:10.1371/journal.pone.0150323. |
pdzrn3 is required for pronephros morphogenesis in Xenopus laevis
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Citation:
Int J Dev Biol. 2016 Mar 2. [Epub ahead of print] Epub:
Yes Abstract:
Pdzrn3, a multidomain protein with E3-ubiquitin ligase activity, has been reported to play a role in myoblast and osteoblast... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L. pdzrn3 is required for pronephros morphogenesis in Xenopus laevis. Int J Dev Biol. 2016 Mar 2. [Epub ahead of print]. |
Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio)
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Citation:
Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print] Epub:
Yes Abstract:
Halogenated carbazoles are increasingly identified as a novel class of environmental contaminants. However, no in vivo acute... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fang M, Guo J, Chen D, Li A, Hinton DE, Dong W. Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio). Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print]. |
The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ
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Citation:
Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print] Epub:
Yes Abstract:
The development of the vertebrate embryonic heart occurs by hyperplastic growth as well as the incorporation of cells from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tandon P, Wilczewski CM, Williams CE, Conlon FL. The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ. Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print]. |
Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement
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Citation:
PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114 Epub:
Not Epub Abstract:
We analyzed the protein distribution of two cadherin-associated molecules, plakoglobin and β-catenin, during the different... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Verstraeten B, van Hengel J, Huysseune A
. Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement. PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114. |
Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy
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Citation:
Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print] Epub:
Yes Abstract:
Familial exudative vitreoretinopathy (FEVR) belongs to a group of genetically and clinically heterogeneous disorders in retinal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY. Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy. Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print]. |
A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies
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Citation:
Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666 Epub:
Not Epub Abstract:
The Src family kinase (SFK) member SRC is a major target in drug development because it is activated in many human cancers, yet... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666. |
Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy
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Citation:
Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print] Epub:
Yes Abstract:
Mitochondria are the site of iron utilization, wherein imported iron is incorporated into heme or iron-sulfur clusters.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L. Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print]. |
Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs
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Citation:
Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3 Epub:
Not Epub Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3. |
Active DNA demethylation at enhancers during the vertebrate phylotypic period
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Citation:
Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print] Epub:
Yes Abstract:
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R. Active DNA demethylation at enhancers during the vertebrate phylotypic period. Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print]. |