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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Sox21 regulates the progression of neuronal differentiation in a dose-dependent manner

Authors:
Whittington N, Cunningham D, Le TK, De Maria D, Silva EM
Citation:
Dev Biol. 2015 Jan 15;397(2):237-47. doi: 10.1016/j.ydbio.2014.11.012. Epub 2014 Nov 20
Epub:
Not Epub
Abstract:
Members of the SoxB transcription factor family play critical roles in the regulation of neurogenesis. The SoxB1 proteins are...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Whittington N, Cunningham D, Le TK, De Maria D, Silva EM. Sox21 regulates the progression of neuronal differentiation in a dose-dependent manner. Dev Biol. 2015 Jan 15;397(2):237-47. doi: 10.1016/j.ydbio.2014.11.012. Epub 2014 Nov 20.

Calcium signaling regulates ventricular hypertrophy during development independent of contraction or blood flow

Authors:
Andersen ND, Ramachandran KV, Bao MM, Kirby ML, Pitt GS, Hutson MR
Citation:
J Mol Cell Cardiol. 2015 Mar;80:1-9. doi: 10.1016/j.yjmcc.2014.12.016. Epub 2014 Dec 20
Epub:
Not Epub
Abstract:
In utero interventions aimed at restoring left ventricular hemodynamic forces in fetuses with prenatally diagnosed hypoplastic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andersen ND, Ramachandran KV, Bao MM, Kirby ML, Pitt GS, Hutson MR. Calcium signaling regulates ventricular hypertrophy during development independent of contraction or blood flow. J Mol Cell Cardiol. 2015 Mar;80:1-9. doi: 10.1016/j.yjmcc.2014.12.016. Epub 2014 Dec 20.

Geometric control of ciliated band regulatory states in the sea urchin embryo

Authors:
Barsi JC, Li E, Davidson EH
Citation:
Development. 2015 Mar 1;142(5):953-61. doi: 10.1242/dev.117986. Epub 2015 Feb 5
Epub:
Not Epub
Abstract:
The trapezoidal ciliated band (CB) of the postgastrular sea urchin embryo surrounds the oral ectoderm, separating it from...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Barsi JC, Li E, Davidson EH. Geometric control of ciliated band regulatory states in the sea urchin embryo. Development. 2015 Mar 1;142(5):953-61. doi: 10.1242/dev.117986. Epub 2015 Feb 5.

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage

Authors:
Gong L, Gong H, Pan X, Chang C, Ou Z, Ye S, Yin L, Yang L, Tao T, Zhang Z, Liu C, Lane DP, Peng J, Chen J
Citation:
Cell Res. 2015 Mar;25(3):351-69. doi: 10.1038/cr.2015.22. Epub 2015 Feb 20
Epub:
Not Epub
Abstract:
The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor-suppressing property. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong L, Gong H, Pan X, Chang C, Ou Z, Ye S, Yin L, Yang L, Tao T, Zhang Z, Liu C, Lane DP, Peng J, Chen J. p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage. Cell Res. 2015 Mar;25(3):351-69. doi: 10.1038/cr.2015.22. Epub 2015 Feb 20.

Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling

Authors:
Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V
Citation:
Oncogene. 2008 Oct 2;27(44):5845-55. doi: 10.1038/onc.2008.202. Epub 2008 Jul 21
Epub:
Not Epub
Abstract:
The canonical Wnt/beta-catenin pathway is a highly conserved signaling cascade that is involved in development and stem cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 2008 Oct 2;27(44):5845-55. doi: 10.1038/onc.2008.202. Epub 2008 Jul 21.

Intraciliary calcium oscillations initiate vertebrate left-right asymmetry

Authors:
Yuan S, Zhao L, Brueckner M, Sun Z
Citation:
Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5
Epub:
Not Epub
Abstract:
BACKGROUND: Bilateral symmetry during vertebrate development is broken at the left-right organizer (LRO) by ciliary motility...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan S, Zhao L, Brueckner M, Sun Z. Intraciliary calcium oscillations initiate vertebrate left-right asymmetry. Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5.

A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT

Authors:
Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q
Citation:
Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23
Epub:
Not Epub
Abstract:
Maternally expressed proteins function in vertebrates to establish the major body axes of the embryo and to establish a pre-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q. A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT. Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23.

Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity

Authors:
Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE
Citation:
Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26
Epub:
Not Epub
Abstract:
Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26.

Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus

Authors:
Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ
Citation:
Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179
Epub:
Not Epub
Abstract:
The basal chordate amphioxus resembles vertebrates in having a dorsal, hollow nerve cord, a notochord and somites. However, it...
Delivery Method:
microinjection
Organism or Cell Type:
Branchiostoma floridae (amphioxis)
Citation Extract:
Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179.

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling

Authors:
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT
Citation:
Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230
Epub:
Not Epub
Abstract:
Wnts are secreted ligands that activate several receptor-mediated signal transduction cascades. Homeostatic Wnt signaling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT . Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230.

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