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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino

Authors:
McGlinchey JC, Tummala H, Lester DH
Citation:
Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print]
Epub:
Yes
Abstract:
The very common GNB3 c.825C>T polymorphism (rs5443) is present in approximately half of all human chromosomes. Significantly...
Link:
http://online.liebertpub.com/doi/10.1089/hum.2015.29005.abstracts
Organism or Cell Type:
cell culture: human lymphoblast cell line ebv transformed
Citation Extract:
McGlinchey JC, Tummala H, Lester DH. Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino. Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print].

4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation

Authors:
Lee J, Fei P, Packard RRS, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Jay Kuo CCJ, Chi NC, Ho C-M, Li R, Hsiai TK
Citation:
JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496
Epub:
Yes
Abstract:
Hemodynamic shear forces are intimately linked with cardiac development, during which trabeculae form a network of branching...
Link:
http://www.jci.org/articles/view/83496
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Fei P, Packard RRS, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Jay Kuo CCJ, Chi NC, Ho C-M, Li R, Hsiai TK. 4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496.

Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo

Authors:
Melchionda M, Pittman JK, Mayor R, Patel S
Citation:
J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019
Epub:
Yes
Abstract:
Increasing evidence implicates Ca2+ in the control of cell migration. However, the underlying mechanisms are incompletely...
Link:
http://jcb.rupress.org/content/212/7/803.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Melchionda M, Pittman JK, Mayor R, Patel S. Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo. J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019.

Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy

Authors:
Li M, Andersson-Lendahl M, Sejersen T, Arner A
Citation:
J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452
Epub:
Not Epub
Abstract:
Myosin-binding protein C (MyBPC) in the muscle sarcomere interacts with several contractile and structural proteins. Mutations...
Link:
http://jgp.rupress.org/content/147/4/309.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li M, Andersson-Lendahl M, Sejersen T, Arner A. Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy. J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452.

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration

Authors:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L
Citation:
Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034
Epub:
Not Epub
Abstract:
A zebrafish genetic screen for determinants of susceptibility to Mycobacterium marinum identified a hypersusceptible mutant...
Link:
http://www.cell.com/fulltext/S0092-8674%2816%2930136-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L. Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034.

Cell-fate determination by ubiquitin-dependent regulation of translation

Authors:
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M
Citation:
Nature. 2015 Sep 24;525(7570):523-7. doi: 10.1038/nature14978
Epub:
Not Epub
Abstract:
Metazoan development depends on the accurate execution of differentiation programs that allow pluripotent stem cells to adopt...
Link:
http://www.nature.com/nature/journal/v525/n7570/full/nature14978.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015 Sep 24;525(7570):523-7. doi: 10.1038/nature14978.

Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition

Authors:
Zhang M, Kothari P, Mullins M, Lampson MA
Citation:
Cell Cycle. 2014;13(24):3828-38. doi: 10.4161/15384101.2014.967066
Epub:
Not Epub
Abstract:
Following fertilization, oviparous embryos undergo rapid, mostly transcriptionally silent cleavage divisions until the mid-...
Link:
http://www.tandfonline.com/doi/full/10.4161/15384101.2014.967066
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang M, Kothari P, Mullins M, Lampson MA. Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition. Cell Cycle. 2014;13(24):3828-38. doi: 10.4161/15384101.2014.967066.

Conditions that influence the response to Fgf during otic placode induction

Authors:
Padanad MS, Bhat N, Guo B, Riley BB
Citation:
Dev Biol. 2012 Apr 1;364(1):1-10. doi: 10.1016/j.ydbio.2012.01.022. Epub 2012 Feb 1
Epub:
Not Epub
Abstract:
Despite the vital importance of Fgf for otic induction, previous attempts to study otic induction through Fgf misexpression...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160612000528
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Padanad MS, Bhat N, Guo B, Riley BB. Conditions that influence the response to Fgf during otic placode induction. Dev Biol. 2012 Apr 1;364(1):1-10. doi: 10.1016/j.ydbio.2012.01.022. Epub 2012 Feb 1.

Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Authors:
Hong N, Li M, Yuan Y, Wang T, Yi M, Xu H, Zeng H, Song J, Hong Y
Citation:
Stem Cell Reports. 2016 Mar 8;6(3):411-21. doi: 10.1016/j.stemcr.2016.01.002. Epub 2016 Feb 4
Epub:
Not Epub
Abstract:
Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse...
Link:
http://www.cell.com/stem-cell-reports/abstract/S2213-6711%2816%2900019-9
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Hong N, Li M, Yuan Y, Wang T, Yi M, Xu H, Zeng H, Song J, Hong Y. Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish. Stem Cell Reports. 2016 Mar 8;6(3):411-21. doi: 10.1016/j.stemcr.2016.01.002. Epub 2016 Feb 4.

GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis

Authors:
Gao X, Wu T, Johnson KD, Lahvic JL, Ranheim EA, Zon LI, Bresnick EH
Citation:
Stem Cell Reports. 2016 Mar 8;6(3):368-82. doi: 10.1016/j.stemcr.2016.01.008. Epub 2016 Feb 18
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) originate from hemogenic endothelium within the aorta-gonad-mesonephros (AGM) region of the...
Link:
http://www.cell.com/stem-cell-reports/abstract/S2213-6711%2816%2900025-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao X, Wu T, Johnson KD, Lahvic JL, Ranheim EA, Zon LI, Bresnick EH. GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis. Stem Cell Reports. 2016 Mar 8;6(3):368-82. doi: 10.1016/j.stemcr.2016.01.008. Epub 2016 Feb 18.

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