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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
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Citation:
Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187 Epub:
Not Epub Abstract:
Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187. |
mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration
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Citation:
Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function... Delivery Method:
peptide-linked Organism or Cell Type:
mice, mdx Citation Extract: Roberts TC, Blomberg KE, Smith CI, El Andaloussi S, Wood MJ. mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration. Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar. |
A ligand-independent integrin β1 mechanosensory complex guides spindle orientation
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Citation:
Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899 Epub:
Not Epub Abstract:
Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Petridou NI, Skourides PA. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899. |
The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity
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Citation:
J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22 Epub:
Not Epub Abstract:
Cranial neural crest (CNC) cells are a transient population of stem cells that originate at the border of the neural plate and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D. The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity. J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22. |
Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology
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Citation:
J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502 Epub:
Not Epub Abstract:
Cilia-driven fluid flow is a critical yet poorly understood aspect of pulmonary physiology. Here, we demonstrate that optical... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, zebrafish Citation Extract: Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA. Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology. J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502. |
β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner
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Citation:
Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012 Epub:
Yes Abstract:
Amyloid precursor protein (APP) is a transmembrane glycoprotein that has been the subject of intense research because of its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Banote RK, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A. β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012. |
Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis
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Citation:
JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461 Epub:
Not Epub Abstract:
The 2p15p16.1 microdeletion syndrome has a core phenotype consisting of intellectual disability, microcephaly, hypotonia,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, Dunham C, Wen J, Wildin RS, Nowaczyk MJM, Eichmeyer J, Lehman A, Maranda B, Martell S, Shan X, Lewis SME, O’Driscoll M, Gregory-Evans CY, Rajcan-Separovic E. Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461. |
Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea)
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Citation:
bioRxiv. 2016. doi:10.1101/044149 Epub:
Yes Abstract:
Developmental gene regulatory networks (dGRNs) are assemblages of interacting regulatory factors that direct ontogeny of animal... Delivery Method:
microinjection Organism or Cell Type:
Eucidaris tribuloides (sea urchin) Citation Extract: Erkenbrack EM. Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea). bioRxiv. 2016. doi:10.1101/044149. |
Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure
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Citation:
Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print] Epub:
Not Epub Abstract:
Our aim was to understand the involvement of Sonic hedgehog (Shh) morphogen in the oriented distribution of neural crest cells... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Tolosa EJ, Fernández-Zapico ME, Battiato NL, Rovasio RA. Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure. Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print]. |
Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation
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Citation:
Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print] Epub:
Yes Abstract:
A well-functioning brain requires production of the correct number and types of cells during development; cascades of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Chen C, Jin J, Lee GA, Silva E, Donoghue M. Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation. Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print]. |