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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation

Authors:
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, Filhol E, Niel O, Silbermann F, Lebreton C, Collardeau-Frachon S, Rouvet I, Alessandri JL, Devisme L, Dieux-Coeslier A, Cordier MP, Capri Y, Khung-Savatovsky S, Sigaudy S, Salomon R, Antignac C, Gubler MC, Benmerah A, Terzi F, Attié-Bitach T, Jeanpierre C, Saunier S
Citation:
PLoS Genet. 2016 Mar 11;12(3):e1005894. doi: 10.1371/journal.pgen.1005894. eCollection 2016 Mar
Epub:
Not Epub
Abstract:
Ciliopathies are a group of genetic multi-systemic disorders related to dysfunction of the primary cilium, a sensory organelle...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, Filhol E, Niel O, Silbermann F, Lebreton C, Collardeau-Frachon S, Rouvet I, Alessandri JL, Devisme L, Dieux-Coeslier A, Cordier MP, Capri Y, Khung-Savatovsky S, Sigaudy S, Salomon R, Antignac C, Gubler MC, Benmerah A, Terzi F, Attié-Bitach T, Jeanpierre C, Saunier S. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genet. 2016 Mar 11;12(3):e1005894. doi: 10.1371/journal.pgen.1005894. eCollection 2016 Mar.

PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration

Authors:
Davey CF, Mathewson AW, Moens CB
Citation:
PLoS Genet. 2016 Mar 18;12(3):e1005934. doi: 10.1371/journal.pgen.1005934. eCollection 2016 Mar
Epub:
Not Epub
Abstract:
The planar cell polarity (PCP) pathway is a cell-contact mediated mechanism for transmitting polarity information between...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davey CF, Mathewson AW, Moens CB. PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet. 2016 Mar 18;12(3):e1005934. doi: 10.1371/journal.pgen.1005934. eCollection 2016 Mar.

ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation

Authors:
Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J
Citation:
Sci Rep. 2016 Mar 23;6:23433. doi: 10.1038/srep23433
Epub:
Not Epub
Abstract:
The lipid mediator lysophosphatidic acid (LPA) signals via six distinct G protein-coupled receptors to mediate both unique and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J. ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Sci Rep. 2016 Mar 23;6:23433. doi: 10.1038/srep23433.

Evolution of the vertebrate claudin gene family: insights from a basal vertebrate, the sea lamprey

Authors:
Mukendi C, Dean N, Lala R, Smith J, Bronner ME, Nikitina NV
Citation:
Int J Dev Biol. 2016;60(1-2-3):39-51
Epub:
Not Epub
Abstract:
Claudins are major constituents of tight junctions, contributing both to their intercellular sealing and selective permeability...
Organism or Cell Type:
Petromyzon marinus (sea lamprey)
Citation Extract:
Mukendi C, Dean N, Lala R, Smith J, Bronner ME, Nikitina NV. Evolution of the vertebrate claudin gene family: insights from a basal vertebrate, the sea lamprey. Int J Dev Biol. 2016;60(1-2-3):39-51.

Evidence for a role of heme oxygenase-1 in the control of cardiac function in zebrafish (Danio rerio) larvae exposed to hypoxia

Authors:
Tzaneva V, Perry SF
Citation:
J Exp Biol. 2016 Mar 18. pii: jeb.136853. [Epub ahead of print]
Epub:
Yes
Abstract:
Carbon monoxide (CO) is a gaseous neurotransmitter produced from the breakdown of heme via heme oxygenase-1 (HO-1; hypoxia...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tzaneva V, Perry SF. Evidence for a role of heme oxygenase-1 in the control of cardiac function in zebrafish (Danio rerio) larvae exposed to hypoxia. J Exp Biol. 2016 Mar 18. pii: jeb.136853. [Epub ahead of print].

Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'

Authors:
Faucherre A, Kissa K, Nargeot J, Mangoni ME, Jopling C
Citation:
Haematologica. 2016 Jan;101(1):e38. doi: 10.3324/haematol.2015.137398
Epub:
Not Epub
Abstract:
No abstract available. Open access.
Citation Extract:
Faucherre A, Kissa K, Nargeot J, Mangoni ME, Jopling C . Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'. Haematologica. 2016 Jan;101(1):e38. doi: 10.3324/haematol.2015.137398.

Authors' response to "Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'"

Authors:
Shmukler BE, Lawson ND, Paw BH, Alper SL
Citation:
Haematologica. 2016 Jan;101(1):e39. doi: 10.3324/haematol.2015.137810
Epub:
Not Epub
Abstract:
No abstract available. Open access.
Citation Extract:
Shmukler BE, Lawson ND, Paw BH, Alper SL. Authors' response to "Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'". Haematologica. 2016 Jan;101(1):e39. doi: 10.3324/haematol.2015.137810.

Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody

Authors:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G
Citation:
Mol Pharm. 2015 Aug 3;12(8):3097-103. doi: 10.1021/mp5008579. Epub 2015 Jul 8
Epub:
Not Epub
Abstract:
Quantitative prediction of in vivo behavior using an in vitro assay would dramatically accelerate pharmaceutical development....
Delivery Method:
injection
Organism or Cell Type:
mice
Citation Extract:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G. Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody. Mol Pharm. 2015 Aug 3;12(8):3097-103. doi: 10.1021/mp5008579. Epub 2015 Jul 8.

Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing

Authors:
De Domenico E, Owens ND, Grant IM, Gomes-Faria R, Gilchrist MJ
Citation:
Dev Biol. 2015 Dec 15;408(2):252-68. doi: 10.1016/j.ydbio.2015.06.010. Epub 2015 Jun 19
Epub:
Not Epub
Abstract:
Correct development of the vertebrate body plan requires the early definition of two asymmetric, perpendicular axes. The first...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
De Domenico E, Owens ND, Grant IM, Gomes-Faria R, Gilchrist MJ. Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing. Dev Biol. 2015 Dec 15;408(2):252-68. doi: 10.1016/j.ydbio.2015.06.010. Epub 2015 Jun 19.

Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis

Authors:
Nworu CU, Kraft R, Schnurr DC, Gregorio CC, Krieg PA
Citation:
J Cell Sci. 2015 Jan 15;128(2):239-50. doi: 10.1242/jcs.152702. Epub 2014 Nov 27
Epub:
Not Epub
Abstract:
Precise regulation of thin filament length is essential for optimal force generation during muscle contraction. The thin...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nworu CU, Kraft R, Schnurr DC, Gregorio CC, Krieg PA. Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis. J Cell Sci. 2015 Jan 15;128(2):239-50. doi: 10.1242/jcs.152702. Epub 2014 Nov 27.

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