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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

E-cadherin is required for cranial neural crest migration in xenopus laevis

Authors:
Huang C, Kratzer MC, Wedlich D, Kashef J
Citation:
Dev Biol. 2016 Feb 12. pii: S0012-1606(16)30076-8. doi: 10.1016/j.ydbio.2016.02.007. [Epub ahead of print]
Epub:
Yes
Abstract:
The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616300768
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Huang C, Kratzer MC, Wedlich D, Kashef J. E-cadherin is required for cranial neural crest migration in xenopus laevis. Dev Biol. 2016 Feb 12. pii: S0012-1606(16)30076-8. doi: 10.1016/j.ydbio.2016.02.007. [Epub ahead of print].

Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome

Authors:
Devotta A, Juraver-Geslin H, Gonzalez JA, Hong CS, Saint-Jeannet JP
Citation:
Dev Biol. 2016 Feb 11. pii: S0012-1606(16)30081-1. doi: 10.1016/j.ydbio.2016.02.010. [Epub ahead of print]
Epub:
Yes
Abstract:
Mandibulofacial dysostosis (MFD) is a human developmental disorder characterized by defects of the facial bones. It is the...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616300811
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Devotta A, Juraver-Geslin H, Gonzalez JA, Hong CS, Saint-Jeannet JP. Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome. Dev Biol. 2016 Feb 11. pii: S0012-1606(16)30081-1. doi: 10.1016/j.ydbio.2016.02.010. [Epub ahead of print].

Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE

Authors:
Sen D, Patel G, Patel SS
Citation:
Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw098
Epub:
Yes
Abstract:
A crucial component of the human mitochondrial DNA replisome is the ring-shaped helicase TWINKLE—a phage T7-gene 4-like protein...
Link:
https://nar.oxfordjournals.org/content/early/2016/02/16/nar.gkw098.full
Citation Extract:
Sen D, Patel G, Patel SS. Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE. Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw098.

Molecular model for force production and transmission during vertebrate gastrulation

Authors:
Pfister K, Shook DR, Chang C, Keller R, Skoglund P.
Citation:
Development. 2016;143:715-727. doi:10.1242/dev.128090
Epub:
Not Epub
Abstract:
Vertebrate embryos undergo dramatic shape changes at gastrulation that require locally produced and anisotropically applied...
Link:
http://dev.biologists.org/content/143/4/715
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pfister K, Shook DR, Chang C, Keller R, Skoglund P.. Molecular model for force production and transmission during vertebrate gastrulation. Development. 2016;143:715-727. doi:10.1242/dev.128090.

Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype

Authors:
Nizzardo M, Simone C, Rizzo F, Ulzi G, Ramirez A, Rizzuti M, Bordoni A, Bucchia M, Gatti S, Bresolin N, Comi GP, Corti S
Citation:
Sci Rep. 2016;6:21301. doi:10.1038/srep21301
Epub:
Not Epub
Abstract:
Neurotoxicity due to the accumulation of mutant proteins is thought to drive pathogenesis in neurodegenerative diseases....
Link:
https://www.nature.com/articles/srep21301
Delivery Method:
electroporation, Vivo-Morpholino, ICV & ip injected bare Morpholino
Organism or Cell Type:
cell culture: HeLa, iPSC-derived motor neurons. mice.
Citation Extract:
Nizzardo M, Simone C, Rizzo F, Ulzi G, Ramirez A, Rizzuti M, Bordoni A, Bucchia M, Gatti S, Bresolin N, Comi GP, Corti S. Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype. Sci Rep. 2016;6:21301. doi:10.1038/srep21301.

Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development

Authors:
Marra AN, Wingert RA
Citation:
Dev Biol. 2016 Jan 29. pii: S0012-1606(15)30106-8. doi: 10.1016/j.ydbio.2016.01.035. [Epub ahead of print]
Epub:
Yes
Abstract:
Kidney development requires the differentiation and organization of discrete nephron epithelial lineages, yet the genetic and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615301068
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Wingert RA. Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development. Dev Biol. 2016 Jan 29. pii: S0012-1606(15)30106-8. doi: 10.1016/j.ydbio.2016.01.035. [Epub ahead of print].

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins

Authors:
Piacentino ML, Zuch DT, Fishman J, Rose S, Speranza EE, Li C, Yu J, Chung O, Ramachandran J, Ferrell P, Patel V, Reyna A, Hameeduddin H, Chaves J, Hewitt FB, Bardot E, Lee D, Core AB, Hogan JD, Keenan JL, Luo L, Coulombe-Huntington J, Blute TA, Oleinik E, Ibn-Salem J, Poustka AJ, Bradham CA
Citation:
Development. 2016 Jan 11. pii: dev.129312. [Epub ahead of print]
Epub:
Yes
Abstract:
The sea urchin larval skeleton offers a simple model for developmental pattern formation. The calcium carbonate skeleton is...
Link:
http://dev.biologists.org/content/143/4/703
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Piacentino ML, Zuch DT, Fishman J, Rose S, Speranza EE, Li C, Yu J, Chung O, Ramachandran J, Ferrell P, Patel V, Reyna A, Hameeduddin H, Chaves J, Hewitt FB, Bardot E, Lee D, Core AB, Hogan JD, Keenan JL, Luo L, Coulombe-Huntington J, Blute TA, Oleinik E, Ibn-Salem J, Poustka AJ, Bradham CA. RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins. Development. 2016 Jan 11. pii: dev.129312. [Epub ahead of print].

Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability

Authors:
Moreno RL, Ribera AB
Citation:
Neural Dev. 2014 Aug 22;9:19. doi: 10.1186/1749-8104-9-19
Epub:
Not Epub
Abstract:
BACKGROUND: In the spinal cord, stereotypic patterns of transcription factor expression uniquely identify neuronal subtypes....
Link:
http://neuraldevelopment.biomedcentral.com/articles/10.1186/1749-8104-9-19
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreno RL, Ribera AB. Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability. Neural Dev. 2014 Aug 22;9:19. doi: 10.1186/1749-8104-9-19.

In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus

Authors:
Barrett GL, Naim T, Trieu J, Huang M
Citation:
J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print]
Epub:
Yes
Abstract:
This study seeks to determine whether knockdown of basal forebrain p75 neurotrophin receptor (p75NTR ) expression elicits...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/jnr.23717/abstract
Delivery Method:
medial septa infusion
Organism or Cell Type:
Rat
Citation Extract:
Barrett GL, Naim T, Trieu J, Huang M. In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus. J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print].

Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation

Authors:
Yoshizaki G, Takashiba K, Shimamori S, Fujinuma K, Shikina S, Okutsu T, Kume S, Hayashi M
Citation:
Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print]
Epub:
Yes
Abstract:
We previously established a spermatogonial transplantation model in fish using triploid recipients. Although triploid salmonids...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mrd.22625/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Oncorhynchus mykiss (rainbow trout)
Citation Extract:
Yoshizaki G, Takashiba K, Shimamori S, Fujinuma K, Shikina S, Okutsu T, Kume S, Hayashi M. Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation. Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print].

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