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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia

Authors:
Fernández-Murray JP, Prykhozhij SV, Dufay JN, Steele SL, Gaston D, Nasrallah GK, Coombs AJ, Liwski RS, Fernandez CV, Berman JN, McMaster CR
Citation:
PLoS Genet. 2016;12(1):e1005783. doi:10.1371/journal.pgen.1005783
Epub:
Not Epub
Abstract:
Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005783
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fernández-Murray JP, Prykhozhij SV, Dufay JN, Steele SL, Gaston D, Nasrallah GK, Coombs AJ, Liwski RS, Fernandez CV, Berman JN, McMaster CR. Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia. PLoS Genet. 2016;12(1):e1005783. doi:10.1371/journal.pgen.1005783.

Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability

Authors:
Kasher PR, Schertz KE, Thomas M, Jackson A, Annunziata S, Ballesta-Martinez MJ, Campeau PM, Clayton PE, Eaton J, Granata T, Guillén-Navarro E, Hernando C, Laverriere CE, Liedén A, Villa-Marcos O, McEntagart M, Nordgren A, Pantaleoni C, Pebrel-Richard C, Sarret C, Sciacca FL, Wright R, Kerr B, Glasgow E, Banka S
Citation:
Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2015.12.014
Epub:
Yes
Abstract:
Genetic studies of intellectual disability and identification of monogenic causes of obesity in humans have made immense...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2815%2900509-1
Organism or Cell Type:
zebrafish
Citation Extract:
Kasher PR, Schertz KE, Thomas M, Jackson A, Annunziata S, Ballesta-Martinez MJ, Campeau PM, Clayton PE, Eaton J, Granata T, Guillén-Navarro E, Hernando C, Laverriere CE, Liedén A, Villa-Marcos O, McEntagart M, Nordgren A, Pantaleoni C, Pebrel-Richard C, Sarret C, Sciacca FL, Wright R, Kerr B, Glasgow E, Banka S. Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability. Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2015.12.014.

Epigenetic regulation of hematopoiesis by DNA methylation

Authors:
Gore AV, Athans B, Iben JR, Johnson K, Russanova V, Castranova D, Pham VN, Butler MG, Williams-Simons L, Nichols JT, Bresciani E, Feldman B, Kimmel CB, Liu PP, Weinstein BM
Citation:
Elife. 2016 Jan 27;5. pii: e11813. doi: 10.7554/eLife.11813.
Epub:
Not Epub
Abstract:
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications...
Link:
http://elifesciences.org/content/5/e11813
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gore AV, Athans B, Iben JR, Johnson K, Russanova V, Castranova D, Pham VN, Butler MG, Williams-Simons L, Nichols JT, Bresciani E, Feldman B, Kimmel CB, Liu PP, Weinstein BM. Epigenetic regulation of hematopoiesis by DNA methylation. Elife. 2016 Jan 27;5. pii: e11813. doi: 10.7554/eLife.11813..

Hmga2 is required for neural crest cell specification in xenopus laevis

Authors:
Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R
Citation:
Dev Biol. 2016 Jan 21. pii: S0012-1606(16)30028-8. doi: 10.1016/j.ydbio.2016.01.014. [Epub ahead of print]
Epub:
Yes
Abstract:
HMGA proteins are small nuclear proteins that bind DNA by conserved AT-hook motifs, modify chromatin architecture and assist in...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616300288
Organism or Cell Type:
Xenopus
Citation Extract:
Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R. Hmga2 is required for neural crest cell specification in xenopus laevis. Dev Biol. 2016 Jan 21. pii: S0012-1606(16)30028-8. doi: 10.1016/j.ydbio.2016.01.014. [Epub ahead of print].

Autosomal-Recessive Hearing Impairment due to Rare Missense Variants within S1PR2

Authors:
Santos-Cortez RL, Faridi R, Rehman AU, Lee K, Ansar M, Wang X, Morell RJ, Isaacson R, Belyantseva IA, Dai H, Acharya A, Qaiser TA, Muhammad D, Ali RA, Shams S, Hassan MJ, Shahzad S, Raza SI, Bashir ZE, Smith JD, Nickerson DA, Bamshad MJ; University of Washington Center for Mendelian Genomics, Riazuddin S, Ahmad W, Friedman TB, Leal SM
Citation:
Am J Hum Genet. 2016 Jan 19. pii: S0002-9297(15)00499-1. doi: 10.1016/j.ajhg.2015.12.004. [Epub ahead of print]
Epub:
Yes
Abstract:
The sphingosine-1-phosphate receptors (S1PRs) are a well-studied class of transmembrane G protein-coupled sphingolipid...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2815%2900499-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Santos-Cortez RL, Faridi R, Rehman AU, Lee K, Ansar M, Wang X, Morell RJ, Isaacson R, Belyantseva IA, Dai H, Acharya A, Qaiser TA, Muhammad D, Ali RA, Shams S, Hassan MJ, Shahzad S, Raza SI, Bashir ZE, Smith JD, Nickerson DA, Bamshad MJ; University of Washington Center for Mendelian Genomics, Riazuddin S, Ahmad W, Friedman TB, Leal SM. Autosomal-Recessive Hearing Impairment due to Rare Missense Variants within S1PR2. Am J Hum Genet. 2016 Jan 19. pii: S0002-9297(15)00499-1. doi: 10.1016/j.ajhg.2015.12.004. [Epub ahead of print].

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Authors:
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang , Chen M-H, Pers TH, <-Authors removed - database limit-> ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Zemunik T, Lehtimaki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Volker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen W-M, Igl W, Marz W, Koenig W, Lieb W, Loos RJF, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Boger CA, Goessling W, Chasman DI, Kottgen A, Kao WHL, Fox CS.
Citation:
Nat Comm. 2016;7:10023. doi:10.1038/ncomms10023
Epub:
Not Epub
Abstract:
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality...
Link:
http://www.nature.com/ncomms/2016/160121/ncomms10023/full/ncomms10023.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang , Chen M-H, Pers TH, <-Authors removed - database limit-> ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Zemunik T, Lehtimaki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Volker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen W-M, Igl W, Marz W, Koenig W, Lieb W, Loos RJF, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Boger CA, Goessling W, Chasman DI, Kottgen A, Kao WHL, Fox CS. . Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Comm. 2016;7:10023. doi:10.1038/ncomms10023.

Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line

Authors:
Carrillo SA, Anguita-Salinas C, Peña OA, Morales RA, Muñoz-Sánchez S, Muñoz-Montecinos C, Paredes-Zúñiga S, Tapia K, Allende ML
Citation:
J Cell Biochem. 2016 Jan 11. doi: 10.1002/jcb.25487. [Epub ahead of print]
Epub:
Yes
Abstract:
In vertebrates, damage to mechanosensory hair cells elicits an inflammatory response, including rapid recruitment of...
Link:
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcb.25487/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carrillo SA, Anguita-Salinas C, Peña OA, Morales RA, Muñoz-Sánchez S, Muñoz-Montecinos C, Paredes-Zúñiga S, Tapia K, Allende ML. Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line. J Cell Biochem. 2016 Jan 11. doi: 10.1002/jcb.25487. [Epub ahead of print].

Vitamin D receptor signaling is required for heart development in zebrafish embryo

Authors:
Kwon HJ
Citation:
Biochem Biophys Res Commun. 2016 Jan 18. pii: S0006-291X(16)30103-6. doi: 10.1016/j.bbrc.2016.01.103. [Epub ahead of print]
Epub:
Yes
Abstract:
Vitamin D has been found to be associated with cardiovascular diseases. However, the role of vitamin D in heart development...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16301036
Organism or Cell Type:
zebrafish
Citation Extract:
Kwon HJ. Vitamin D receptor signaling is required for heart development in zebrafish embryo. Biochem Biophys Res Commun. 2016 Jan 18. pii: S0006-291X(16)30103-6. doi: 10.1016/j.bbrc.2016.01.103. [Epub ahead of print].

Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach

Authors:
Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J
Citation:
Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print]
Epub:
Yes
Abstract:
Defects in mRNA 3' end formation have been described to alter transcription termination, transport of the mRNA from the...
Link:
http://hmg.oxfordjournals.org/content/early/2016/01/19/hmg.ddw015.abstract
Delivery Method:
DNA leash and lipofectamine
Organism or Cell Type:
cell culture: differentiated immortalized FSHD myotubes
Citation Extract:
Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J. Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach. Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print].

Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action

Authors:
Marelli F, Carra S, Agostini M, Cotelli F, Peeters R, Chatterjee K, Persani L
Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Resistance to thyroid hormone can be due to heterozygous, dominant negative (DN) THRA (RTHα) or THRB (RTHβ) mutations, but the...
Link:
http://www.sciencedirect.com/science/article/pii/S030372071630020X
Organism or Cell Type:
zebrafish
Citation Extract:
Marelli F, Carra S, Agostini M, Cotelli F, Peeters R, Chatterjee K, Persani L. Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print].

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